2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013713
    Riboflavin phosphate sodium hydrate
    Riboflavine phosphate sodium hydrate (Riboflavine 5'-phosphate sodium hydrate) is a derivative of Riboflavin (vitamin B2) which is an essential nutrient for animals. Riboflavine phosphate sodium hydrate can be used for the research of progressive keratoconus, corneal ectasia and irregular astigmatism. Riboflavine phosphate sodium hydrate is a very effective NAD+-recycling agent.
    Riboflavin phosphate sodium hydrate
  • HY-137823
    4-Nitrophenyl-N-acetyl-β-D-galactosaminide
    		Inhibitor 99.55%
    4-Nitrophenyl-N-acetyl-β-D-galactosaminide has inhibitory activity against GlcNAc and GalNAc with Kis of 1.15 mM and 0.51 mM, respectively. 4-Nitrophenyl-N-acetyl-β-D-galactosaminide is extracted from Trichomonas foetus (T. foetus)
    4-Nitrophenyl-N-acetyl-β-D-galactosaminide
  • HY-N0394S4
    L-Cystine-3,3'-13C2
    		99.0%
    L-Cystine-3,3'-13C2 is the 13C labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
    L-Cystine-3,3'-<sup>13</sup>C<sub>2</sub>
  • HY-113316A
    (±)-Salsolinol hydrochloride
    		98%
    (±)-Salsolinol hydrochloride is the hydrochloride form of (±)-Salsolinol (HY-113316). (±)-Salsolinol hydrochloride is a Dopamine (HY-B0451)-derived endogenous metabolite. (±)-Salsolinol hydrochloride activates μ-opioid receptors (MORs), reduces GABAergic transmission, increases the excitability of dopamine (DA) neurons, and thus accelerates the sustained firing of neurons in the posterior ventral tegmental area (pVTA).
    (±)-Salsolinol hydrochloride
  • HY-N0470S8
    L-Lysine-13C6 hydrochloride
    		98.0%
    L-Lysine-13C6 hydrochloride is the 13C labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
    L-Lysine-<sup>13</sup>C<sub>6</sub> hydrochloride
  • HY-113226
    Orotidine
    Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants.
    Orotidine
  • HY-B0400S
    D-Sorbitol-d8
    		98.0%
    D-Sorbitol-d8 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement.
    D-Sorbitol-d<sub>8</sub>
  • HY-N0492R
    α-Lipoic Acid (Standard)
    α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1.
    α-Lipoic Acid (Standard)
  • HY-15121R
    L-Theanine (Standard)
    L-Theanine (Standard) is the analytical standard of L-Theanine. This product is intended for research and analytical applications. L-Theanine (L-Glutamic Acid γ-ethyl amide) is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective, anticancer and anti-oxidative activities. L-Theanine can pass through the blood–brain barrier and is orally active.
    L-Theanine (Standard)
  • HY-W751165
    Uridine-13C9, 15N2
    		99.0%
    Uridine-13C9,15N2 (β-Uridine-13C9,15N2) is 13C and 15N labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
    Uridine-<sup>13</sup>C<sub>9</sub>, <sup>15</sup>N<sub>2</sub>
  • HY-128753
    D-Lyxose
    		98.0%
    D-Lyxose is an endogenous metabolite. D-Lyxose is a rare pentose sugar with significant potential for drug synthesis. D-Lyxose can be used as a starting material for anti-tumor drugs such as alpha galactose ceramide immunostimulants. D-Lyxose can be used as a precursor for L-nucleoside analogs for the development of antiviral drugs. D-Lyxose can be used as a synthetic intermediate for other rare sugars such as L-ribose.
    D-Lyxose
  • HY-116374S
    Glycolithocholic acid-d4
    		98.38%
    Glycolithocholic acid-d4 is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .
    Glycolithocholic acid-d<sub>4</sub>
  • HY-W010736
    1,2-Dipalmitoyl-sn-glycerol
    		98.0%
    1,2-Dipalmitoyl-sn-glycerol is an endogenous metabolite.
    1,2-Dipalmitoyl-sn-glycerol
  • HY-W016009R
    2'-Deoxyadenosine-5'-monophosphate (Standard)
    2'-Deoxyadenosine-5'-monophosphate (Standard) is the analytical standard of 2'-Deoxyadenosine-5'-monophosphate. This product is intended for research and analytical applications. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
    2'-Deoxyadenosine-5'-monophosphate (Standard)
  • HY-125527S
    Resolvin D1-d5
    		99.2%
    Resolvin D1-d5 is the deuterium labeled Resolvin D1. Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α-mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.
    Resolvin D1-d<sub>5</sub>
  • HY-W039157
    2-Acetyl-3-ethylpyrazine
    		99.88%
    2-Acetyl-3-ethylpyrazine is an endogenous metabolite.
    2-Acetyl-3-ethylpyrazine
  • HY-N0229S10
    L-Alanine-13C3,15N
    		98.0%
    L-Alanine-13C3,15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-N0470S
    L-Lysine-15N2 hydrochloride
    		98.0%
    L-Lysine-15N2 (hydrochloride) is the 15N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
    L-Lysine-<sup>15</sup>N<sub>2</sub> hydrochloride
  • HY-Y1091
    D-Lysine
    D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance.
    D-Lysine
  • HY-N3500
    Ganoderic acid D2
    		99.69%
    Ganoderic acid D2 (compound 27) is a triterpenoid isolated from Ganoderma lucidum. Ganoderic acid D2 has anticancer, anti-inflammatory and antioxidative activity.
    Ganoderic acid D2
Cat. No. Product Name / Synonyms Application Reactivity