2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0229S13
    L-Alanine-d7
    		99.83%
    L-Alanine-d7 is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
    L-Alanine-d<sub>7</sub>
  • HY-W011195
    Calcium 2-hydroxy-4-(methylthio)butanoate
    Calcium 2-hydroxy-4-(methylthio)butanoate is an endogenous metabolite.
    Calcium 2-hydroxy-4-(methylthio)butanoate
  • HY-128749A
    D-Glucaric acid tetrahydrate
    		≥98.0%
    D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the mammalian D-glucuronidation pathway. D-Glucaric acid tetrahydrate is found in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate induces cell Apoptosis. D-Glucaric acid tetrahydrate reduces the expression of hippocampal myelin-related genes (Mbp, Plp1). D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can be used in the research of neurological diseases.
    D-Glucaric acid tetrahydrate
  • HY-W016887R
    Glycyl-L-proline (Standard)
    H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.
    Glycyl-L-proline (Standard)
  • HY-B0892S2
    Benzyl alcohol-d5
    		99.05%
    Benzyl alcohol-d5 is the deuterium labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.
    Benzyl alcohol-d<sub>5</sub>
  • HY-B1716S2
    L-5-Hydroxytryptophan-d4
    		98.71%
    L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist. L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia.
    L-5-Hydroxytryptophan-d<sub>4</sub>
  • HY-110406
    13(S)-HPODE
    13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.
    13(S)-HPODE
  • HY-B0351R
    Taurine (Standard)
    Taurine (Standard) is the analytical standard of Taurine. This product is intended for research and analytical applications. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
    Taurine (Standard)
  • HY-W006267
    4-Chloroindole-3-acetic acid
    		99.96%
    4-Chloroindole-3-acetic acid (4-Cl-IAA) is a chlorinated analogue of indole-3-acetic acid (IAA) (HY-18569) auxin that functions as a plant hormone, which is found in the seeds of Medicago truncatula、Melilotus indicus and Trifolium.
    4-Chloroindole-3-acetic acid
  • HY-113152
    Hypogeic acid
    		98.0%
    Hypogeic acid can be isolated from autotrophic bacterial cultures associated with the accumulation of sulfate in biofilters.
    Hypogeic acid
  • HY-B1449S8
    Uridine-d2-1
    		98.47%
    Uridine-d2-1 is the deuterium labeled Uridine.
    Uridine-d<sub>2</sub>-1
  • HY-N0568R
    Madecassoside (Standard)
    Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB, exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.
    Madecassoside (Standard)
  • HY-Z0283S
    Benzamide-15N
    		99.87%
    Benzamide-15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP).
    Benzamide-<sup>15</sup>N
  • HY-W141932
    N-Stearoylglycine
    		99.95%
    N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films.
    N-Stearoylglycine
  • HY-N0326S10
    L-Methionine-d4
    L-Methionine-d4 is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
    L-Methionine-d<sub>4</sub>
  • HY-118472
    Benazeprilat
    		99.54%
    Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage.
    Benazeprilat
  • HY-B0649S1
    Propofol-d18
    Propofol-d18 is the deuterium labeled Propofol. Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission.
    Propofol-d<sub>18</sub>
  • HY-113139S
    1-Methylinosine-d3
    		≥99.0%
    1-Methylinosine-d3 is the deuterium labeled 1-Methylinosine. 1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA.
    1-Methylinosine-d<sub>3</sub>
  • HY-N0684S
    Vitamin K1-d7
    		98.0%
    Vitamin K1-d7 is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
    Vitamin K1-d<sub>7</sub>
  • HY-N0830S12
    Palmitic acid-d4-1
    		99.80%
    Palmitic acid-d4-1 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Palmitic acid-d<sub>4</sub>-1
Cat. No. Product Name / Synonyms Application Reactivity