2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W585842
    Estradiol 3-glucuronide
    		98.00%
    Estradiol 3-glucuronide is an immunogen with antigenic properties. Estradiol 3-glucuronide induced antiserum in the rabbit possesses high afinity and specifcity to Estradiol 3-glucuronide. Estradiol 3-glucuronide is promising for research of radioimmunoassay.
    Estradiol 3-glucuronide
  • HY-Y0264R
    4-Hydroxybenzoic acid (Standard)
    4-Hydroxybenzoic acid (Standard) is the analytical standard of 4-Hydroxybenzoic acid. This product is intended for research and analytical applications. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.
    4-Hydroxybenzoic acid (Standard)
  • HY-N1132R
    D-(+)-Trehalose (Standard)
    Etamivan (Standard) is the analytical standard of Etamivan. This product is intended for research and analytical applications. Etamivan (Ethamivan), an orally active respiratory stimulant, is mainly used in the research of barbiturate overdose and chronic obstructive pulmonary disease.
    D-(+)-Trehalose (Standard)
  • HY-113423
    Tetrahydro-11-deoxycortisol
    		98.20%
    Tetrahydro-11-deoxycortisol (Tetrahydrodeoxycortisol) is an endogenous metabolite present in Urine that can be used for the research of 11 Beta Hydroxylase Deficiency.
    Tetrahydro-11-deoxycortisol
  • HY-101409R
    O-Acetylserine (Standard)
    O-Acetylserine (Standard) is the analytical standard of O-Acetylserine. This product is intended for research and analytical applications. O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.
    O-Acetylserine (Standard)
  • HY-W020249
    Sodium ionophore X
    		98.0%
    Sodium ionophore X, a substituted calixarene, exhibits remarkably high ionophoric properties for metal ions and serves as a synergistic agent in the solvent extraction of lanthanoids alongside a thenoyltrifluoroacetone compound. Additionally, it plays a crucial role in the preparation of potentiometric membranes.
    Sodium ionophore X
  • HY-W016562R
    Hippuric acid (Standard)
    Hippuric acid (Standard) is the analytical standard of Hippuric acid. This product is intended for research and analytical applications. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research. .
    Hippuric acid (Standard)
  • HY-B0456S3
    Riboflavin-d3
    		99.40%
    Riboflavin-d3 is the deuterium labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-d<sub>3</sub>
  • HY-111825A
    (R)-1-PeCSO
    		99.50%
    (R)-1-PeCSO (trans-(+)-S-1-Propenyl-L-cysteine sulfoxide) is the most abundant flavor precursor in onions.
    (R)-1-PeCSO
  • HY-W009749CS
    (S)-Cystathionine-d4
    (S)-Cystathionine-d4 is the deuterium labeled (S)-Cystathionine.
    (S)-Cystathionine-d<sub>4</sub>
  • HY-164690A
    Nicotinamide-guanine dinucleotide sodium
    Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro.
    Nicotinamide-guanine dinucleotide sodium
  • HY-N0832R
    L-Histidine (Standard)
    L-Histidine (Standard) is the analytical standard of L-Histidine. This product is intended for research and analytical applications. L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
    L-Histidine (Standard)
  • HY-N2026S1
    Propylparaben-d4
    		99.00%
    Propylparaben-d4 is the deuterium labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats.
    Propylparaben-d<sub>4</sub>
  • HY-N2027S
    Taurochenodeoxycholic acid-d4 sodium
    		99.20%
    Taurochenodeoxycholic acid-d4 (sodium) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.
    Taurochenodeoxycholic acid-d<sub>4</sub> sodium
  • HY-107780
    Cyclic-di-GMP
    		98.18%
    Cyclic-di-GMP is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP can be used in cancer research.
    Cyclic-di-GMP
  • HY-101411S
    4-Acetamidobutanoic acid-d3
    4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities.
    4-Acetamidobutanoic acid-d<sub>3</sub>
  • HY-W012926S1
    Dihydrouracil-d4
    		99.97%
    Dihydrouracil-d4 is the deuterium labeled Dihydrouracil. Dihydrouracil (HY-W012926), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient.
    Dihydrouracil-d<sub>4</sub>
  • HY-N4068R
    Glucoraphanin (Standard)
    Glucoraphanin (Standard) is the analytical standard of Glucoraphanin. This product is intended for research and analytical applications. Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.
    Glucoraphanin (Standard)
  • HY-B0141S3
    Estradiol-d2
    		99.44%
    Estradiol-d2 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway.
    Estradiol-d<sub>2</sub>
  • HY-Y1055S
    Guanine-13C
    		99.5%
    Guanine-13C is the 13C labeled Guanine. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
    Guanine-<sup>13</sup>C
Cat. No. Product Name / Synonyms Application Reactivity