2. Signaling Pathways
  3. Metabolic Enzyme/Protease
    Vitamin D Related/Nuclear Receptor
  4. LXR
  5. LXR Inhibitor

LXR Inhibitor

LXR Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-N0835
    (20S)-Protopanaxatriol
    		Inhibitor 99.93%
    (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects.
  • HY-124418
    SBI-477
    		Inhibitor ≥98.0%
    SBI-477 is a chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA. SBI-477 can lead to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.
  • HY-128671
    6-​Thioinosine
    		Inhibitor 99.31%
    6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction.
  • HY-N0835R
    (20S)-Protopanaxatriol (Standard)
    		Inhibitor
    (20S)-Protopanaxatriol (Standard) is the analytical standard of (20S)-Protopanaxatriol. This product is intended for research and analytical applications. (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects.
  • HY-RS09529
    NR1H2 Human Pre-designed siRNA Set A
    		Inhibitor

    NR1H2 Human Pre-designed siRNA Set A contains three designed siRNAs for NR1H2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS09530
    NR1H3 Human Pre-designed siRNA Set A
    		Inhibitor

    NR1H3 Human Pre-designed siRNA Set A contains three designed siRNAs for NR1H3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-139007
    BLT-4
    		Inhibitor
    BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI). BLT-4 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. .
  • HY-N3867
    Ethyl 2,4,6-trihydroxybenzoate
    		Inhibitor
    Ethyl 2,4,6-trihydroxybenzoate (Benzoic acid, 2,4,6-trihydroxy-, ethyl ester) is a Triterpenoids product that can be isolated from the herbs of Pueraria lobata.