2. Signaling Pathways
  3. Anti-infection
  4. HBV
  5. HBV Agonist

HBV Agonist

HBV Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-176507
    DF-006
    		Agonist
    DF-006 is a first-in-class orally active agonist of ALPK1 (α-kinase 1). DF-006 can stimulate the innate immune response by activating the NF-κB pathway and strongly stimulate the innate immunity in the liver locally. DF-006 reduces the levels of serum HBV DNA (EC50 = 2.7 pM), HBsAg and HBeAg, and has shown strong antiviral effects. DF-006 is suitable for research on the immunotherapy of chronic hepatitis B (CHB).