1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W011540S
    8-Hydroxy-2'-deoxyguanosine-15N5
    99.5%
    8-Hydroxy-2'-deoxyguanosine-15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis.
    8-Hydroxy-2'-deoxyguanosine-<sup>15</sup>N<sub>5</sub>
  • HY-W006057AS17
    Sodium 3-Methyl-2-oxobutanoic acid-13C2
    99.90%
    3-Methyl-2-oxobutanoic acid-13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli.
    Sodium 3-Methyl-2-oxobutanoic acid-<sup>13</sup>C<sub>2</sub>
  • HY-145656
    3-Oxochenodeoxycholic acid
    99.92%
    3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19.
    3-Oxochenodeoxycholic acid
  • HY-B1654S
    Flavin adenine dinucleotide-13C5 ammonium
    Flavin adenine dinucleotide-13C5 (FAD-13C5) ammonium is 13C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
    Flavin adenine dinucleotide-<sup>13</sup>C<sub>5</sub> ammonium
  • HY-127061
    Palmitoleoyl ethanolamide
    99.77%
    Palmitoleoyl ethanolamide (POEA) is an endogenous fatty amide with biological activity.
    Palmitoleoyl ethanolamide
  • HY-168761
    N-Cholyl-L-alanine
    99.2%
    N-Cholyl-L-alanine is a bile acid amidate, which is found in human fecal samples.
    N-Cholyl-L-alanine
  • HY-W016568
    Isoxanthopterin
    99.68%
    Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering.
    Isoxanthopterin
  • HY-W010759
    Inosine-5′-monophosphate disodium salt octahydrate
    98.0%
    Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP.
    Inosine-5′-monophosphate disodium salt octahydrate
  • HY-113434S
    5(S)-HETE-d8
    99.2%
    5(S)-HETE-d8 is the deuterium labeled 5(S)-HETE.
    5(S)-HETE-d<sub>8</sub>
  • HY-B1391R
    D-Panthenol (Standard)
    D-Panthenol (Standard) is the analytical standard of D-Panthenol. This product is intended for research and analytical applications. D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell. D-panthenol exhibits nephroprotective effect in AKI, promotes tissue repair and regeneration.
    D-Panthenol (Standard)
  • HY-66005S4
    Acetaminophen-13C2,15N
    98.30%
    Acetaminophen-13C2,15N is the 13C and 15N labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-W013049S1
    Docosanoic acid-d43
    99.29%
    Docosanoic acid-d43 (Behenic acid-d43) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans.
    Docosanoic acid-d<sub>43</sub>
  • HY-122046
    Amb123203
    98.87%
    Amb123203 is an antiviral compound with the activity of inhibiting viral budding. Amb123203 exerts its effect by blocking the interaction between mVP40 and Nedd4 proteins. Amb123203 has a significant inhibitory effect on the budding of VP40 virus-like particles (VLPs) of Marburg (MARV) and Ebola viruses. Amb123203 can effectively target RNA viruses that rely on the PPxY L domain for efficient budding, showing broad-spectrum antiviral activity. The discovery of Amb123203 provides an important basis for the development of new broad-spectrum antiviral compounds.
    Amb123203
  • HY-W010918R
    Adenosine 5'-diphosphate (Standard)
    Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.
    Adenosine 5'-diphosphate (Standard)
  • HY-W012814S2
    4-Methylimidazole-d6
    98.3%
    4-Methylimidazole-d6 is the deuterium labeled 4-Methylimidazole.
    4-Methylimidazole-d<sub>6</sub>
  • HY-W052051
    N-Benzylacetamide
    99.35%
    N-Benzylacetamide (N-Acetylbenzylamine), as an endogenous metabolite, is the major component of the plasma metabolic profile of Benznidazole (HY-B1548).
    N-Benzylacetamide
  • HY-N7392A
    Acetoacetyl-CoA sodium hydrate
    Acetoacetyl CoA sodium hydrate is the precursor of HMG-CoA in the mevalonate pathway. Acetoacetyl-CoA thiolase catalyzes the reaction to form acetoacetyl-CoA sodium hydrate from two acetyl-CoA molecules. Acetoacetyl CoA sodium hydrate is essential for cholesterol biosynthesis. Acetoacetyl-CoA sodium hydrate is also a intermediate in the biological breakdown and synthesis of fatty acids.
    Acetoacetyl-CoA sodium hydrate
  • HY-131309
    12-Doxylstearic acid
    99.00%
    12-Doxyl stearic acid is a form of stearic acid that contains a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, creating a hydrophobic spin label. It is commonly used to study molecular aspects of membranes and hydrophobic proteins.
    12-Doxylstearic acid
  • HY-113093S
    Ethyl glucuronide-d5
    Ethyl glucuronide-d5 is the deuterium labeled Ethyl glucuronide (HY-113093). Ethyl glucuronide is an endogenous metabolite. Ethyl glucuronide is the metabolite of ethanol. Ethyl glucuronide is a biomarker for ethanol exposure that accumulates in hair and reflects the alcohol intake over a time period. Ethyl glucuronide is the agonist for TLR4.
    Ethyl glucuronide-d<sub>5</sub>
  • HY-W015495R
    L-Dihydroorotic acid (Standard)
    L-Dihydroorotic acid (Standard) is an analytical reference standard for L-Dihydroorotic acid. This product is used for research and analytical applications. L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme.
    L-Dihydroorotic acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity