1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-176247
    DHFS-IN-1
    Inhibitor
    DHFS-IN-1 (Compound 3) is a dihydrofolate synthetase (DHFS) inhibitor with an IC50 value of 2.6 μM. DHFS-IN-1 can be used in research on infectious diseases related to bacterial folate synthesis.
    DHFS-IN-1
  • HY-N14845
    Napsamycin A
    Inhibitor
    Napsamycin A is an antibiotic. Napsamycin A has antibacterial activity against Pseudomonas aeruginosa and other pseudomonas, but has weak antibacterial activity against other Gram-positive and negative bacteria.
    Napsamycin A
  • HY-108989
    FMDP
    FMDP is an inhibitor of GlcN-6-P Synthase with an anti-candidal activity. FMDP can be covalently attached to a polyethylene glycol as a nanoparticle shows strong anticancer activity.
    FMDP
  • HY-106291
    Cefclidin
    Inhibitor
    Cefclidin (Cefclidine) belongs to the cephalomycin-type compound.
    Cefclidin
  • HY-B1894R
    Cefetamet pivoxyl (Standard)
    Inhibitor
    Cefetamet pivoxyl (Standard) is the analytical standard of Cefetamet pivoxyl. This product is intended for research and analytical applications. Cefetamet pivoxyl is a cephalosporin antibiotic. Cefetamet pivoxyl inhibits 355 enteropathogens Keime, Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila.
    Cefetamet pivoxyl (Standard)
  • HY-N14512
    Quinolactacin C
    Quinolactacin C is a quinolone found in Penicillum sp. EPF-6.
    Quinolactacin C
  • HY-126577
    Dactylocycline B
    Inhibitor
    Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria.
    Dactylocycline B
  • HY-W099582
    Myristamidopropyl dimethylamine
    Inhibitor
    Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .
    Myristamidopropyl dimethylamine
  • HY-W793613
    Drimendiol
    Inhibitor
    Drimendiol (compound 1) is an active product that can be isolated from leaves and twigs of D. winterii. Drimendiol shows inhibition for C. albicans, S. aureus, and S. epidermidis biofilm formation with 50% biofilm inhibitory concentration values (BIC50s) of 25.5, 65.1, and 67.1 µg/ml, respectively.
    Drimendiol
  • HY-N14156
    Epelmycin B
    Inhibitor
    Epelmycin B has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
    Epelmycin B
  • HY-N14233
    Inosamycin A
    Inhibitor
    Inosamycin A is a broad-spectrum antimicrobial antibiotic.
    Inosamycin A
  • HY-N13895
    Auramycin B
    Inhibitor
    Auramycin B, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin B also exhibits antitumor activity against P388 and L1210 leukemia in mice.
    Auramycin B
  • HY-169810
    PKZ18
    Inhibitor
    PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.
    PKZ18
  • HY-W414697
    4-Hydroxysphinganine (C17 base)
    Inhibitor
    4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.
    4-Hydroxysphinganine (C17 base)
  • HY-159899
    DHFR-IN-22
    Inhibitor
    DHFR-IN-22 (Compound 8) is a DHFR (Dihydrofolate Reductase) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus, and an IC50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections.
    DHFR-IN-22
  • HY-138796
    Griseolutein A
    Inhibitor
    Griseolutein A shows activitiy against Gram-positive and negative bacteria.
    Griseolutein A
  • HY-145462
    N-cis-Octadec-9Z-enoyl-L-homoserine lactone
    N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a potent inhibitor of AhyI. AhyI (expressing acylhomoserine lactone) is responsible for the biosynthesis of autoinducer-1 (AI-1), commonly referred to as a quorum sensing (QS) signaling molecule, which plays an essential role in bacterial communication. N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a competitive inhibitor of AI-1 biosynthesis.
    N-cis-Octadec-9Z-enoyl-L-homoserine lactone
  • HY-B1894AR
    Cefetamet pivoxil hydrochloride (Standard)
    Inhibitor
    Cefetamet pivoxil (hydrochloride) (Standard) is the analytical standard for Cefetamet pivoxil (hydrochloride). This product is intended for research and analytical applications. Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.
    Cefetamet pivoxil hydrochloride (Standard)
  • HY-N14969
    Granaticin methyl ester
    Inhibitor
    Granaticin methyl ester is a quinone antibiotic. Granaticin methyl ester has anti-Gram positive bacteria and negative bacteria activity.
    Granaticin methyl ester
  • HY-B1123R
    Auranofin (Standard)
    Inhibitor
    Auranofin (Standard) is the analytical standard of Auranofin. This product is intended for research and analytical applications. Auranofin (SKF-39162) is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21, with a CC50 of 4.2 μM for monkey kidney Vero E6 cells.
    Auranofin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity