2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-160669
    Antibacterial agent 198
    		Inhibitor
    Antibacterial agent 198 (Compound 16) is an antibacterial agent against gram positive Staphylococcus aureus and strains of Entercoccus.
    Antibacterial agent 198
  • HY-N7123S1
    Sulfacetamide-13C6
    		Inhibitor
    Sulfacetamide-13C6 (Sulphacetamide13C6) is the 13C6 labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.
    Sulfacetamide-<sup>13</sup>C<sub>6</sub>
  • HY-143292
    Antibacterial agent 81
    		Inhibitor
    Antibacterial agent 81 is a DNA transcription inhibitor. Antibacterial agent 81 inhibits S. aureus USA300 and M. smegmatis ATCC14468 with MIC values of 12.5 and 7.8 μM, respectively. Antibacterial agent 81 can be used for the research of infection.
    Antibacterial agent 81
  • HY-W725641
    Tricyclazole-d3
    		Inhibitor
    Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
    Tricyclazole-d<sub>3</sub>
  • HY-B0147S
    Pefloxacin-d5
    		Inhibitor 98.33%
    Pefloxacin-d5 (Pefloxacinium-d5) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
    Pefloxacin-d<sub>5</sub>
  • HY-147349A
    Pilabactam
    		Inhibitor
    Pilabactam (ANT3310) is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase). Pilabactam potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB). Pilabactam can be used in the research of bacterial infection.
    Pilabactam
  • HY-P5678
    Bombinin H4
    		Inhibitor
    Bombinin H4 is an antimicrobial peptide derived from the skin of moth Bombina variegata. The lethal concentrations of Bombinin H4 against Escherichia coli D21 and Staphylococcus aureus Cowan 1 are 4.8 and 3.3 μM, respectively.
    Bombinin H4
  • HY-155504
    Metallo-β-lactamase-IN-11
    		Inhibitor
    Metallo-β-lactamase-IN-11 (compound 5f) is a Metallo-β-lactamases (MBLs) inhibitor, potent against bacterial metallophyllactamase CphA (IC50=45 µM). Metallo-β-lactamase-IN-11 (10 µM) inhibits NDM-1 by 49% and AIM-1 by 61%. Metallo-β-lactamase-IN-11 can be used in the research of inhibiting antibiotic resistance.
    Metallo-β-lactamase-IN-11
  • HY-177540
    ent-Rhizocarpic acid
    		Inhibitor
    ent-Rhizocarpic acid is an enantiomer of Rhizocarpic acid. ent-Rhizocarpic acid has more potent antibacterial and antiparasitic activity against Staphylococcus aureus (ATCC 25923) and Giardiaduodenalis 713 compared to Rhizocarpic acid. ent-Rhizocarpic acid also has a weak but selective antitumor activity against NS-1 cells.
    ent-Rhizocarpic acid
  • HY-P5672
    Maximin 39
    		Inhibitor
    Maximin 39 is an antimicrobial peptide derived from the toad brain. Maximin 39 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 18.8, 37.5 μg/mL, respectively.
    Maximin 39
  • HY-106597
    Pirlimycin
    		Inhibitor
    Pirlimycin, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.
    Pirlimycin
  • HY-106959
    Flurithromycin
    		Inhibitor 99.73%
    Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections.
    Flurithromycin
  • HY-163042
    HSGN-218
    		Inhibitor
    HSGN-218 is an antibacterial agent with low Caco-2 permeability. HSGN-218 efficiently inhibits the growth of different C. difficile species with MIC values ranging from 0.007 μM to 0.07 μM.
    HSGN-218
  • HY-133671S
    Monooctyl phthalate-d4
    		Inhibitor
    Monooctyl phthalate-d4 (Mono-n-octyl phthalate-d4) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL.
    Monooctyl phthalate-d<sub>4</sub>
  • HY-121076
    Berteroin
    		Inhibitor
    Berteroin, a naturally occurring Sulforaphane analog, ia an antimetastatic agent. Berteroin has anti-inflammatory, antitumor and bactericidal effects.
    Berteroin
  • HY-168948
    Quorum sensing-IN-9
    		Inhibitor
    Quorum sensing-IN-9 (Compound 7d) inhibits quorum sensing in Pseudomonas aeruginosa by binding PqsR proteins. Quorum sensing-IN-9 inhibits the expression of quorum sensing systems related genes lasB, rhlA and pqsA, blocks the generation of virulence factors elastase, pyocyanin and rhamnolipid. Quorum sensing-IN-9 destorys the motility of P. aeruginosa, inhibits the biofilm formation, decreasing the virulence and pathogenicity of P. aeruginosa. Quorum sensing-IN-9 exhibits anti-infectious activity in Galleria mellonella larval model.
    Quorum sensing-IN-9
  • HY-W245806S1
    1-Methylnaphthalene-13C
    1-Methylnaphthalene-13C is the 13C-labeled 1-Methylnaphthalene (HY-166872). 1-Methylnaphthalene is an organic compound with antibacterial and antioxidant activities. 1-Methylnaphthalene is used as a pollutant indicator in environmental monitoring. 1-Methylnaphthalene can also be used as an intermediate for petrochemical products, helping to improve reaction efficiency during the synthesis process.
    1-Methylnaphthalene-<sup>13</sup>C
  • HY-P5666
    Maximin 15
    		Inhibitor
    Maximin 15 is an antimicrobial peptide derived from the toad brain. Maximin 15 is active against Staphylococcus aureus, Escherichia coli and Bacillus subtilis, with MIC values of 9.4, 18.8, 75 μg/mL, respectively.
    Maximin 15
  • HY-N2026S
    Propylparaben-d7
    		Inhibitor
    Propylparaben-d7 (Propyl parahydroxybenzoate-d7) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats.
    Propylparaben-d<sub>7</sub>
  • HY-P5668
    Maximin 28
    		Inhibitor
    Maximin 28 is an antimicrobial peptide derived from the toad brain. Maximin 28 is active against Staphylococcus aureus, Escherichia coli and Bacillus subtilis, with MIC values of 4.7, 9.4, 75 μg/mL, respectively.
    Maximin 28
Cat. No. Product Name / Synonyms Application Reactivity