2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1241A
    Dihydrostreptomycin
    		Inhibitor
    Dihydrostreptomycin (DHSM) is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss.
    Dihydrostreptomycin
  • HY-17006R
    Caspofungin diacetate (Standard)
    Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan.
    Caspofungin diacetate (Standard)
  • HY-113614
    Tetrahydrobostrycin
    		Inhibitor
    Tetrahydrobostrycin is a secondary metabolite from Aspergillus sp., which exhibits a weak inhibitory activity against Staphylococcus aureus and Escherichia coli (100 mg/disc with the inhibition zones of 15 and 9.2 mm in diameter).
    Tetrahydrobostrycin
  • HY-151340
    Antitubercular agent-32
    		Inhibitor
    Antitubercular agent-32 is a derivate of Benzothiazinone (HY-13579A), inhibits M. tuberculosis, and shows improved metabolic stability and enhanced water solubility. Antitubercular agent-32 exerts antitubercular effect by targeting decaprenylphosphoryl-β-D-ribose 2’-oxidase (DprE1, IC50=3.9 μM).
    Antitubercular agent-32
  • HY-169154
    ChlaDUB1-IN-1
    		Inhibitor
    ChlaDUB1-IN-1 (Compound 8) is an inhibitor for Chlamydia deubiquitinase 1 (ChlaDUB1). ChlaDUB1-IN-1 can be used in antimicrobial research.
    ChlaDUB1-IN-1
  • HY-P3025
    Salmine sulfate
    		Inhibitor
    Salmine sulfate is an antimicrobial protein. Salmine sulfate is a polycationic coacervate embolic agent that can be used in tumor research.
    Salmine sulfate
  • HY-172912
    Anti-MRSA agent 27
    		Inhibitor
    Anti-MRSA agent 27 (compound 4a) is a potent anti-methicillin-resistant Staphylococcus aureus agent with a MIC of 0.0975 μmol/L. Anti-MRSA agent 27 disrupts MRSA biofilms and suppresses hemolytic toxin production.
    Anti-MRSA agent 27
  • HY-P5626
    Seabream hepcidin
    		Inhibitor
    Seabream hepcidin is an antimicrobial peptide with anti-bacterial (V.anguillarum), fungal (S.cerevisiae) and viral hemorrhagic septicemia virus activity.
    Seabream hepcidin
  • HY-10211S
    Tanespimycin-d5
    Tanespimycin-d5 (17-AAG-d5; NSC 330507-d5; CP 127374-d5) is the deuterium labeled Tanespimycin (HY-10211). Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression.
    Tanespimycin-d<sub>5</sub>
  • HY-162564
    Antibacterial agent 221
    		Inhibitor
    Antibacterial agent 221 (compound 3k) is a potent inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 221 shows significant cytotoxicity against human LO2 and HepG2 cells.
    Antibacterial agent 221
  • HY-143484
    844-TFM
    		Inhibitor
    844-TFM is a NBTI (novel bacterial topoisomerase inhibitor) DNA gyrase inhibitor, with an IC50 of 1.5 μM. 844-TFM exhibits bactericidal properties against M. abscessus.
    844-TFM
  • HY-155510
    DprE1-IN-5
    		Inhibitor
    DprE1-IN-5 (Compound 10) is a DprE1 inhibitor. DprE1-IN-5 has anti-TB activity against Mtb H37Rv strain (MIC: 4 μM). DprE1-IN-5 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-5 has high microsomal stability.
    DprE1-IN-5
  • HY-Y0366S4
    Lauric acid-13C-1
    		Inhibitor
    Lauric acid-13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
    Lauric acid-<sup>13</sup>C-1
  • HY-109855
    CP-67015
    		Inhibitor
    CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects.
    CP-67015
  • HY-157492
    RO7075573
    		Inhibitor
    RO7075573 (compound 3) is an antibiotics that targets the lipopolysaccharide (LPS) transport machine in Acinetobacter. RO7075573 protects mice from A. baumannii infections.
    RO7075573
  • HY-162144
    BDM91288
    		Inhibitor
    BDM91288 is an orally active AcrB efflux pump inhibitor of pyridinium piperazine. BDM91288 can enhance the in vivo efficacy of levofloxacin (HY-B0330) in the treatment of Klebsiella pneumoniae pulmonary infection in mouse models.
    BDM91288
  • HY-P5739
    Mram 8
    		Inhibitor
    Mram 8 is a cyclotide isolated from Viola philippica, a plant from the Violaceae family.
    Mram 8
  • HY-116479
    Citromycetin
    		Inhibitor
    Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp.
    Citromycetin
  • HY-157372
    Peptone Bacteriological
    		Inhibitor
    Peptone Bacteriological is used as a medium material to provide nitrogen source and amino acid for bacterial growth.
    Peptone Bacteriological
  • HY-119815
    Tenonitrozole
    		Inhibitor
    Tenonitrozole exhibits antibacterial activity through inhibition of pyruvate-ferredoxin oxidoreductase (PFOR). Tenonitrozole inhibits H. pylori and C. jejuni with MICs of 0.7 μM and 5.9 μM.
    Tenonitrozole
Cat. No. Product Name / Synonyms Application Reactivity