2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. ATGL
  5. ATGL Activator

ATGL Activator

ATGL Activators (2):

Cat. No. Product Name Effect Purity
  • HY-157416
    COP1-ATGL modulator 1
    		Activator 99.31%
    COP1-ATGL modulator 1 (86) is an orally active modulator for COP1-ATGL axis. COP1-ATGL modulator 1 (86) could increase ATGL protein expression, reduce ATGL ubiquitination and COP1 autoubiquitination, and diminish lipid accumulation in hepatocytes in the nanomolar range.
  • HY-111953
    SR-4559
    		Activator
    SR-4559 (Compound 4) is a α/β hydrolase domain-containing protein 5 (ABHD5) ligand. SR-4559 activates adipose triglyceride lipase (ATGL) and stimulates lipolysis by inhibiting ABHD5-PLIN interactions in adipocytes and muscle cells. SR-4559 can be used for metabolic diseases like Chanarin Dorfman syndrome research