2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. 3β-HSD
  5. 3β-HSD I Isoform
  6. 3β-HSD I Inhibitor

3β-HSD I Inhibitor

3β-HSD I Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-14281
    Trilostane
    		Inhibitor 99.81%
    Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer.
  • HY-175592
    HEAL-116
    		Inhibitor
    HEAL-116 is a potent, specific and orally active 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor with an IC50 of 1.18 μM and a KD of 1.32 μM. HEAL-116 inhibits DHEA (HY-14650) metabolism and DHEA-induced target gene expression and cell proliferation. HEAL-116 can be used for cancer research, such as prostate cancer.