1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-U00289
    Opigolix 912587-25-8
    Opigolix (ASP-1707) is a Gonadotropin-releasing hormone (GnRH) receptor antagonist, used for the research of endometriosis and rheumatoid arthritis.
    Opigolix
  • HY-U00293
    ZK-90055 hydrochloride 84638-81-3
    ZK-90055 hydrochloride is a β2 adrenergic receptor agonist.
    ZK-90055 hydrochloride
  • HY-U00299
    LTB4-IN-1 133012-00-7
    LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM.
    LTB4-IN-1
  • HY-U00320
    Neurokinin antagonist 1 214487-45-3
    Neurokinin antagonist 1 is a Neurokinin antagonist extracted from patent WO1998045262A1.
    Neurokinin antagonist 1
  • HY-U00321
    A2B receptor antagonist 1 531506-36-2
    A2B receptor antagonist 1 is a potent A2B adenosine receptor antagonist extracted from patent WO 2009157938 A1 EXAMPLE 9B.
    A2B receptor antagonist 1
  • HY-U00330
    TRPV antagonist 1 1192871-27-4
    TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist, with an IC50 of < 250 nM.
    TRPV antagonist 1
  • HY-U00347
    COX/5-LO-IN-1 154355-75-6
    COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor of cylooxygenase and 5-lipoxygenase (5-LO), used for the research of inflammatory and allergic disease states.
    COX/5-LO-IN-1
  • HY-U00352
    PDE IV-IN-1 225100-12-9
    PDE IV-IN-1 is an inhibitor of phosphodiesterase IV, used for the research of asthma, COPD or other inflammatory diseases.
    PDE IV-IN-1
  • HY-U00355
    YM158 free base 179102-65-9
    YM158 free base is a potent and selective LTD4 and TXA2 receptor antagonist with pA2 values of about 8.87 and 8.81, respectively.
    YM158 free base
  • HY-U00359
    LTD4 antagonist 1 136564-67-5
    LTD4 antagonist 1 is a potent, orally active antagonist of leukotriene D4 (LTD4) with a Ki of 0.57 nM.
    LTD4 antagonist 1
  • HY-U00364
    CI-949 104961-19-5
    CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
    CI-949
  • HY-U00366
    S1PR1-MO-1 1149727-61-6
    S1PR-MO-1 is the modulator of sphingosine-1-phosphate receptor, used for research of hyperproliferative, inflammatory diseases.
    S1PR1-MO-1
  • HY-U00384
    Diarylalkane derivative 1 191155-65-4
    Diarylalkane derivative 1 is used for the research of pancreatitis.
    Diarylalkane derivative 1
  • HY-U00397
    CB1 antagonist 1 890037-68-0
    CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.
    CB1 antagonist 1
  • HY-U00405
    Bronchospasmolytic agent 1 63516-10-9
    Bronchospasmolytic agent 1, a synthetic flutropium bromide compound, acts as a bronchospasmolytic agent.
    Bronchospasmolytic agent 1
  • HY-U00406
    BTM-1086 72293-17-5
    BTM-1086 is a potent anti-ulcer and gastric secretory inhibiting agent.
    BTM-1086
  • HY-U00409
    Antiasthmatic Compound 1 63768-49-0
    Antiasthmatic Compound 1 is an antiasthmatic agent, which has the potential for allergic asthma treatment.
    Antiasthmatic Compound 1
Cat. No. Product Name / Synonyms Application Reactivity