2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0656AS1
    Rabeprazole-d3 sodium 1216494-11-9 98%
    Rabeprazole-d3 sodium the deuterium labeled Rabeprazole sodium (HY-B0656A). Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an b>IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-d3 sodium
  • HY-B0656AS2
    Rabeprazole-d4 potassium 98%
    Rabeprazole-d4 potassium is deuterated labeled Rabeprazole potassium. Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an b>IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole-d4 potassium
  • HY-B1322AS1
    Amodiaquine-d10 hydrochloride 98%
    Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
    Amodiaquine-d10 hydrochloride
  • HY-B1355AS1
    Oxyphenbutazone-13C6 98%
    Oxyphenbutazone-13C6 is the 13C6 labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis.
    Oxyphenbutazone-13C6
  • HY-N0830S14
    Palmitic acid-d17 81462-28-4 98%
    Palmitic acid-d17 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
    Palmitic acid-d17
  • HY-W002004S
    4-Amino-TEMPO-d17,15N 97461-87-5 98%
    4-Amino-TEMPO-d17,15N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d17,15N) is the deuterium labeled 4-Amino-TEMPO-d17 (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others.
    4-Amino-TEMPO-d17,15N
  • HY-W002116S
    Methyl syringate-d6 1182838-09-0 98%
    Methyl syringate-d6 is the deuterium labeled Methyl syringate. Methyl syringate is a selective TRPA1 agonist. Methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway. Methyl syringate is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a chemical marker of Asphodel monofloral honey. Methyl syringate contributes to the antibacterial activity of honey. Methyl syringate inhibits aflatoxin production. Methyl syringate can contribute to weight suppression. Methyl syringate can be studies for cancer prevention (e.g. lung cancer), suppression of hypoxia-induced inflammatory response and tumorigenesis.
    Methyl syringate-d6
  • HY-W002484R
    3-Hydroxy-4-methoxyacetophenone (Standard) 6100-74-9
    3-Hydroxy-4-methoxyacetophenone (Standard) is the analytical standard of 3-Hydroxy-4-methoxyacetophenone. This product is intended for research and analytical applications. 3-Hydroxy-4-methoxyacetophenone(Acetoisovanillone; Isoacetovanillone) is an active compound isolated from P. spinosa. Isoacetovanillone possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon.
    3-Hydroxy-4-methoxyacetophenone (Standard)
  • HY-W003467R
    Rabeprazole Sulfide (Standard) 117977-21-6
    Rabeprazole Sulfide (Standard) is the analytical standard of Rabeprazole Sulfide. This product is intended for research and analytical applications. Rabeprazole Sulfide is an active metabolite of Rabeprazole. Rabeprazole is a proton pump inhibitor that suppresses gastric acid secretion through an interaction with (H+/K+)-ATPase in gastric parietal cells. Rabeprazole markedly inhibits the motility of H. pylori. Rabeprazole has the potential for various peptic diseases treatment.
    Rabeprazole Sulfide (Standard)
  • HY-W003607R
    3-O-Ethyl-L-ascorbic acid (Standard) 86404-04-8
    3-O-Ethyl-L-ascorbic acid (Standard) is the analytical reference standard for 3-O-Ethyl-L-ascorbic acid. 3-O-Ethyl-L-ascorbic acid is a stable derivative of vitamin C and a cosmetic tyrosinase inhibitor. 3-O-Ethyl-L-ascorbic acid has antioxidant, anti-aging, and skin-whitening activities. 3-O-Ethyl-L-ascorbic acid is often used in the study of cosmetic.
    3-O-Ethyl-L-ascorbic acid (Standard)
  • HY-W004049R
    3-Hydroxybenzoic acid (Standard) 99-06-9
    3-Hydroxybenzoic acid (Standard) is the analytical standard of 3-Hydroxybenzoic acid. This product is intended for research and analytical applications. 3-Hydroxybenzoic acid is an orally active endogenous metabolite. 3-Hydroxybenzoic acid is an agonist for GPR81 and GPR109A. 3-Hydroxybenzoic acid acts as stress response desensitizers. 3-Hydroxybenzoic acid can be used for anti-inflammatory and analgesic study.
    3-Hydroxybenzoic acid (Standard)
  • HY-W004291R
    Methyl arachidate (Standard) 1120-28-1
    Methyl arachidate (Standard) is the analytical standard of Methyl arachidate. This product is intended for research and analytical applications. Methyl arachidate (Methyl eicosanoate), a natural compound, is a leukotriene A4 hydrolase (LTA4H) inhibitor.
    Methyl arachidate (Standard)
  • HY-W004295S
    1-Pentadecanol-d31 349553-87-3 98%
    1-Pentadecanol-d31 is the deuterium labeled 1-Pentadecanol. 1-Pentadecanol is a naturally occurring antiacne agent.
    1-Pentadecanol-d31
  • HY-W005327R
    1-Hydroxy-2-butanone (Standard) 5077-67-8
    1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone. This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].
    1-Hydroxy-2-butanone (Standard)
  • HY-W008613R
    Pamoic acid (Standard) 130-85-8
    Pamoic acid (Standard) is the analytical standard of Pamoic acid. This product is intended for research and analytical applications. Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. Pamoic acid exhibits neuroprotective and anti-inflammatory properties.
    Pamoic acid (Standard)
  • HY-W009640A
    Mofebutazone sodium 41468-34-2 98%
    Mofebutazone sodium, a monophenyl analogue of Phenylbutazone (HY-B0230), is an orally active anti-inflammatory agent. Mofebutazone sodium is used in asthma research.
    Mofebutazone sodium
  • HY-W009706A
    Alclofenac sodium 24049-18-1 98%
    Alclofenac sodium is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac sodium is a prostaglandin H2 synthase inhibitor. Alclofenac sodium can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research.
    Alclofenac sodium
  • HY-W009706B
    Alclofenac (lysinate) 59960-34-8 98%
    Alclofenac lysinate is a non-steroidal anti-inflammatory agent (NSAID). Alclofenac lysinate is a prostaglandin H2 synthase inhibitor. Alclofenac lysinate can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research.
    Alclofenac (lysinate)
  • HY-W010037S
    2-(tert-Butyl)-4-methoxyphenol-d3 85013-37-2 98%
    2-(tert-Butyl)-4-methoxyphenol-d3 is deuterium labeled 2-(tert-Butyl)-4-methoxyphenol.
    2-(tert-Butyl)-4-methoxyphenol-d3
  • HY-W010270A
    Aurothiomalate disodium 74916-57-7 98%
    Aurothiomalate (disodium) is a TRPA1 inhibitor. Aurothiomalate (disodium) inhibits NF-κB activation and iNOS expression. Aurothiomalate (disodium) promotes M2 transformation of macrophages and increases the expression of TREM-2 and arginase-1. Aurothiomalate (disodium) can be used in the study of liver fibrosis/cirrhosis and arthritis.
    Aurothiomalate disodium
Cat. No. Product Name / Synonyms Application Reactivity