2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105192
    CP-122288 143321-74-8 98%
    CP-122288, a highly potent inhibitor of neurogenic inflammation, can be used in migraine study.
    CP-122288
  • HY-105198
    Lexipafant 139133-26-9 98%
    Lexipafant is a platelet-activating factor (PAF) antagonist that inhibits the inflammatory response and is used in the research of acute pancreatitis.
    Lexipafant
  • HY-105215
    FK888 138449-07-7 98%
    FK888 is a potent, selective, and high affinity dipeptide NK1 receptor antagonist. FK888 displaces [3H]-SP binding with a Ki value of 0.69 nM and 0.45 microM. FK888 also inhibits SP-induced airway oedema in guinea-pig after both intravenous and oral administration.
    FK888
  • HY-105220
    WY-47766 134217-27-9 98%
    WY-47766(OST-766) is aproton pumpinhibitor.
    WY-47766
  • HY-105396
    L 670630 133174-26-2 98%
    L 670630 is a potent and orally active inhibitor of 5-lipoxygenase, with the IC50 of 23 nM.
    L 670630
  • HY-105507
    PF-10040 132928-46-2 98%
    PF-10040 is a quinoline derivative that can inhibit PAF-induced airway hyperresponsiveness. PF-10040 also shows protective effect in experimental NSAID-gastritis.
    PF-10040
  • HY-105579
    Isonixin 57021-61-1 98%
    Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation.
    Isonixin
  • HY-105630
    Pipebuzone 27315-91-9 98%
    Pipebuzone (LD 4644) is an anti-inflammatory, antipyretic and analgesic agent. Pipebuzone plays an important raol in rheumatic diseases.
    Pipebuzone
  • HY-105641
    Morazone 6536-18-1 98%
    Morazone is a non-steroidal anti-inflammatory drug (NSAID).
    Morazone
  • HY-105698
    Clofexamide 1223-36-5 98%
    Clofexamide (ANP 246; Amichlophene) is a potent antidepressant agent. Clofexamide also shows anti-inflammatory activity.
    Clofexamide
  • HY-105825
    Sermetacin 57645-05-3 98%
    Sermetacin (SH-G 318AB) is an anti-inflammatory agent with biocompatibility and anti-inflammatory activity. Sermetacin is stable in saline and suitable for compound delivery. Sermetacin exhibits good biocompatibility in the RAW 264.7 mouse macrophage cell line. The anti-inflammatory response of sermetacin is comparable to that of its parent compound, indomethacin. Sermetacin may show potential in future applications of self-delivery of compound delivery.
    Sermetacin
  • HY-105852
    Proxazole 5696-09-3 98%
    Proxazole (Propoxaline) is an anti-inflammatory agent. Proxazole prevents Indomethacin (HY-14397)-induced ulcers without anti-secretory effect. Proxazole is also a spasmolytic papaverine-like agent.
    Proxazole
  • HY-105939
    Isofezolac 50270-33-2 98%
    Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties.
    Isofezolac
  • HY-106006
    RV-1729 1293915-42-0 98%
    RV-1729 is an inhibitor of the phosphatidylinositol 3-kinase-δ (PI3Kδ). RV-1729 identifies inhibition of the PI3K isotype by quantifying the release of phosphatidylinositol 3,4, 5-triphosphate (PIP3) (IC50=12 nM), showing twice the selectivity for PI3Kδ relative to PI3Kγ. RV-1729 is also 16 times more selective to PI3Kα. RV-1729 regulates immune and inflammatory responses by inhibiting PI3Kδ. RV-1729 can be used in studies of asthma and chronic obstructive pulmonary disease (COPD).
    RV-1729
  • HY-106027
    Romazarit 109543-76-2 98%
    Romazarit (RO 31-3948) is an anti-inflammatory agent with antirheumatic effect. Romazarit exhibits PPARα agonist activity. Romazarit (30 mg/kg) inhibits the development of hindpaw inflammation in an adjuvant arthritis model.
    Romazarit
  • HY-106050
    Tilomisole 58433-11-7 98%
    Tilomisole (Wy 18251) is a benzimidazothiazole experimental agent with anti-inflammatory activity. Tilomisole causes less agranulocytosis than levamisole, but retains immunomodulating capabilities. Tilomisole is orally active. Tilomisole has the potential for the research of cancer and inflammation.
    Tilomisole
  • HY-106054
    Nocloprost 79360-43-3 98%
    Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist. Nocloprost inhibits evoked [3H]ACh release. Nocloprost has gastroprotective and ulcer-healing properties. Nocloprost accelerates the healing of chronic gastric ulcerations and enhances mucosal growth in rats.
    Nocloprost
  • HY-106055
    Murabutide 74817-61-1 98%
    Murabutide is a safe synthetic immunomodulator. Murabutide can reduce CD4 and CCR5 receptor expression and secrete high levels of beta-chemokines. Murabutide enhances nonspecific resistance against viral infections. Murabutide did not affect virus entry, reverse transcriptase activity or early proviral DNA formation in the cytoplasm of infected cells.
    Murabutide
  • HY-106076
    REV 2871 80263-73-6 98%
    REV 2871 (Eclazolast; CHBZ) is a potent and oral activity antiallergic agent. REV 2871 also is an irreversibility histamine release (HR) inhibitor.
    REV 2871
  • HY-106078
    Oxmetidine 72830-39-8 98%
    Oxmetidine (SKF 92994) is an orally active H2-receptor antagonist, and is an anti-ulcer agent.
    Oxmetidine
Cat. No. Product Name / Synonyms Application Reactivity