2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P2519
    Protease-Activated Receptor-3 (PAR-3) (1-6), human 1872435-09-0 98%
    Protease-Activated Receptor-3 (PAR-3) (1-6), human is a proteinase-activated receptor (PAR-3) agonist peptide.
    Protease-Activated Receptor-3 (PAR-3) (1-6), human
  • HY-P2520
    Influenza HA (110-119) 132031-50-6 98%
    Influenza HA (110-119) is the 110-119 fragment of influenza virus hemagglutinin that can stimulate Treg cells proliferation.
    Influenza HA (110-119)
  • HY-P2561
    Influenza Matrix Protein (61-72) 1286245-45-1 98%
    Influenza Matrix Protein (61-72) is a peptide fragment derived from matrix protein of influenza viruses, corresponds to amino acids 61-72. Influenza Matrix Protein (61-72) is a specific epitope which can induce CD4+ T-cell response.
    Influenza Matrix Protein (61-72)
  • HY-P2564
    Human PD-L1 inhibitor III 2135542-84-4 98%
    Human PD-L1 inhibitor III is a human PD-L1 inhibitor.
    Human PD-L1 inhibitor III
  • HY-P2588
    Osteocalcin (human) 136461-80-8 98%
    Osteocalcin (human) is a vitamin K-dependent bone specific protein. Osteocalcin (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces.
    Osteocalcin (human)
  • HY-P2617
    Ac-WEHD-AFC 210344-99-3 98%
    Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation.
    Ac-WEHD-AFC
  • HY-P2630
    Suc-YVAD-pNA 208264-84-0 98%
    Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases).
    Suc-YVAD-pNA
  • HY-P2642
    Peptide 78 132116-62-2 98.13%
    Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA).
    Peptide 78
  • HY-P2710
    Noxiustoxin 85205-49-8 98%
    Noxiustoxin is a toxin from the venom of the Mexican scorpion Centruroides noxius which block voltage-dependent potassium channel (Kv1.3, IC50 = 360 nM), and calcium-activated potassium channel. Noxiustoxin plays an important role in neuroinflammatory disease.
    Noxiustoxin
  • HY-P2712
    Chemerin-9, mouse 686324-96-9 98%
    Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC50 = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis.
    Chemerin-9, mouse
  • HY-P2791
    Tertiapin (reduced) 58694-52-3 98%
    Tertiapin (reduced) is a kind of synthesis of melittin, its Cys3-Cys14 and Cys5-Cys18 between containing a disulfide bond. Tertiapin (reduced) is a kind of inward rectifier potassium channels blockers, can block the activity of calcium activates large conductance potassium channels. Tertiapin (reduced) can be used for research in diseases such as rheumatoid arthritis and multiple sclerosis.
    Tertiapin (reduced)
  • HY-P2794
    G0775 2098663-92-2 98%
    G0775 is a molecule with potent, broad-spectrum activity against Gram-negative bacteria. G0775 is active against MDR bacteria. G0775 binds the LepB protease domain.
    G0775
  • HY-P3003
    Cereulide 157232-64-9 98%
    Cereulide, a toxin depsipeptide, can be produced by Bacillus cereus. Cereulide induces cell apoptosis. Cereulide acts on mitochondria, leading to dysfunction in different organs (liver, pancreatic islet, brain, intestines, etc.) and body systems (immune system and nervous system).
    Cereulide
  • HY-P3012
    Cathepsin G 107200-92-0 98%
    Cathepsin G acts as a potent agonist of human platelet activation leading to their aggregation., and can be used for screening of relevant inhibitors.
    Cathepsin G
  • HY-P3071
    ShK toxin 172450-46-3 98%
    ShK toxin blocks voltage-dependent potassium channel (Kv1.3 channel). ShK toxin can be isolated from the whole body extract of the Caribbean sea anemone (Stichodactylu helianthus). ShK toxin competes with dendrotoxin I and α-dendrotoxin for binding to synaptosomal membranes of rat brain, facilitates acetylcholine release. ShK toxin suppresses K+ currents in cultured rat dorsal root ganglion neurons. ShK toxin also inhibits T lymphocyte proliferation.
    ShK toxin
  • HY-P3073
    Myelin Basic Protein (1-11) 106128-98-7 98%
    Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE).
    Myelin Basic Protein (1-11)
  • HY-P3083
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg 125678-68-4 98%
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat.
    N-Myristoyl-Lys-Arg-Thr-Leu-Arg
  • HY-P3107
    Homodestcardin 917382-84-4 98%
    Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM.
    Homodestcardin
  • HY-P3129
    KRAS G13D peptide, 25 mer 145019-94-9 98%
    KRAS G13D peptide, 25 mer, a KRAS activating oncogene mutation peptide, is an immune potentiator extracted from patent WO2018144775A1. KRAS G13D peptide, 25 mer can be used to prepare KRAS vaccine.
    KRAS G13D peptide, 25 mer
  • HY-P3130
    Stresscopin-related peptide (human) 348626-74-4 98%
    Stresscopin-related peptide (human) is a specific ligand for the type 2 CRH receptor. Stresscopin-related peptide (human) suppresses food intake, delayed gastric emptying and decreases heat-induced edema. Stresscopin-related peptide (human) maintains homeostasis after stress, and can be used in the research of stress-related diseases.
    Stresscopin-related peptide (human)
Cat. No. Product Name / Synonyms Application Reactivity