2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P1330
    Purotoxin 1 1396322-38-5 98%
    Purotoxin 1 is a P2X3 receptor inhibitor. Purotoxin 1 shows antinociceptive properties in animal models of inflammatory pain. Purotoxin 1 can be isolated from the venom of the wolf spider Geolycosa sp.
    Purotoxin 1
  • HY-P1358
    Alisporivir intermediate-1 882506-05-0 99.83%
    Alisporivir intermediate-1 is an intermediate in the synthesis of Alisporivir. Alisporivir is used for the treatment of inflammatory and viral diseases.
    Alisporivir intermediate-1
  • HY-P1377
    Caffeic acid-pYEEIE 507471-72-9 98%
    Caffeic acid-pYEEIE, a non-phosphopeptide inhibitor, exhibits potent binding affinity for the GST-Lck-SH2 domain.
    Caffeic acid-pYEEIE
  • HY-P1405
    Pam3CSK4-Biotin 1429504-10-8 98%
    Pam3CSK4-Biotin is biotinylated Pam3CSK4. Pam3CSK4-Biotin is a Toll-like receptor 1/2 (TLR1/2) agonist.
    Pam3CSK4-Biotin
  • HY-P1417
    TDFA 1345019-64-8 98%
    TDFA is an irreversible inhibitor of protein arginine deiminase 4 (PAD4).
    TDFA
  • HY-P1426
    AmmTX3 98%
    AmmTX3 is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 is specific blocker of Kv4 channel. AmmTX3 inhibits the A-type K+ current (Ki: 131 nM).
    AmmTX3
  • HY-P1493
    Fibrinopeptide B, human 36204-23-6 98%
    Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.
    Fibrinopeptide B, human
  • HY-P1533
    CRF, bovine 92307-52-3 98%
    CRF, bovine is a potent agonist of CRF receptor, and displaces [125I-Tyr]ovine CRF with a Ki of 3.52 nM.
    CRF, bovine
  • HY-P1535
    Secretin, porcine 17034-34-3 98%
    Secretin, porcine (Porcine secretin acetate) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.
    Secretin, porcine
  • HY-P1572
    Handle region peptide, rat 749227-53-0 98%
    Handle region peptide, rat is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye.
    Handle region peptide, rat
  • HY-P1576
    AMARA peptide 163560-19-8 98%
    AMARA peptide is a substrate for SIK and AMPK.
    AMARA peptide
  • HY-P1577
    Dermorphin Analog 115814-08-9 98%
    Dermorphin Analog is an analog of Dermorphin. Dermorphin is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin.
    Dermorphin Analog
  • HY-P1590
    Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) 247171-44-4 98%
    Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2.
    Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9)
  • HY-P1604
    ATX-II 60748-45-0 98%
    ATX-II is a specific Na+ channel Modulator toxin that can be isolated from the venom of sea anemone (Anemonia sulcata). ATX-II causes delayed inactivation of the Na+
    ATX-II
  • HY-P1640
    (Trp63,Trp64)​-​C3a(63-77) 130154-64-2 98%
    (Trp63,Trp64)​-​C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively.
    (Trp63,Trp64)​-​C3a(63-77)
  • HY-P1699
    Aurantimycin A 162478-50-4 98%
    Aurantimycin A (Adipogen), a depsipeptide antibiotic, displays strong activity against Gram-positive bacteria. Aurantimycin A is a substrate of the LieAB transporter.
    Aurantimycin A
  • HY-P1735
    Moth Cytochrome C (MCC) (88-103) 108273-68-3 98%
    Moth Cytochrome C (MCC) (88-103), derived from the carboxyl terminus of moth cytochrome c, induces positive selection of TCR transgenic thymocytes.
    Moth Cytochrome C (MCC) (88-103)
  • HY-P1745
    InsB (9-23) 163364-16-7 98%
    InsB (9-23) is an insulin B-chain peptide that binds to a class II histocompatibility complex (MHC) allele called I-Ag7. InsB (9-23) can be used to treat a number of autoimmune related diseases like Type 1 diabetes.
    InsB (9-23)
  • HY-P1771
    OVA G4 peptide 148274-82-2 98%
    OVA G4 peptide is a variant of the agonist ovalbumin (OVA) peptide SIINFEKL (257-264). SIINFEKL is routinely used to stimulate ovalbumin-specific T cells and to test new vaccine adjuvants can form a stable hydrogel.
    OVA G4 peptide
  • HY-P1773
    IGF-I (30-41) 82177-09-1 98%
    IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
    IGF-I (30-41)
Cat. No. Product Name / Synonyms Application Reactivity