2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6245
    Daphylloside 14260-99-2 98%
    Daphylloside is an iridoid isolated from the aerial parts of Galium verum.
    Daphylloside
  • HY-N6261
    Epimagnolin B 1134188-26-3 98%
    Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects.
    Epimagnolin B
  • HY-N6672
    Caulophylline B 1359978-55-4 98%
    Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical.
    Caulophylline B
  • HY-N6770
    Curvularin 10140-70-2 98%
    Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM.
    Curvularin
  • HY-N6800
    Netropsin 1438-30-8 98%
    Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity.
    Netropsin
  • HY-N6827
    Usaramine N-oxide 117020-54-9 ≥99.0%
    Usaramine N-oxide, a alkaloid isolated from Crotalaria pallida, possesses anti-inflammatory activities.
    Usaramine N-oxide
  • HY-N6894
    Pseudocoptisine acetate 30426-66-5 98%
    Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects.
    Pseudocoptisine acetate
  • HY-N6902
    Linderene acetate 26146-28-1 99.31%
    Linderene acetate, isolated from the root of Lindera strychnifolia, is a prolyl endopeptidase inhibitor.
    Linderene acetate
  • HY-N6907
    Dahurinol 38908-87-1 99.31%
    Dahurinol is a natural compound isolated from Cimicifuga acerina.
    Dahurinol
  • HY-N7002
    Nagarine 41849-35-8 98%
    Nagarine, an alkaloid isolated from the roots of Aconitum nagarum Stapf (Ranunculaceae), is used to treat Rheumatic and neuralgic disorders.
    Nagarine
  • HY-N7011
    Epicorynoxidine 58000-48-9 98%
    Epicorynoxidine, a natural alkaloid, shows cytotoxic effects P-388 cell line with an ED50 of 25.53 μg/mL.
    Epicorynoxidine
  • HY-N7018
    20-Hydroxyganoderic Acid G 400604-12-8 98%
    20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS.
    20-Hydroxyganoderic Acid G
  • HY-N7155
    2,4,7-Trihydroxy-9,10-dihydrophenanthrene 70205-52-6 98%
    2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene derivative that can be isolated from the air-dried whole plant of Pholidota chinensis Lindl.. 2,4,7-Trihydroxy-9,10-dihydrophenanthrene shows potent activities of IC50 at 16.2 μM in DPPH radical-scavenging assay.
    2,4,7-Trihydroxy-9,10-dihydrophenanthrene
  • HY-N7156
    2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone 33900-74-2 98%
    2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone, isolated from Parinari hypochrysea (Chrysobalanaceae), exhibits antioxidant and lipoxygenase inhibition.
    2,3,4'-Trihydroxy-3',5'-dimethoxypropiophenone
  • HY-N7166
    3-O-(2'E,4'Z-Decadienoyl)ingenol 84680-59-1 98%
    3-O-(2'E,4'Z-Decadienoyl)ingenol is a natural diterpene that exhibits significant anticomplement activity with an IC50 of 89.5 μM.
    3-O-(2'E,4'Z-Decadienoyl)ingenol
  • HY-N7182
    9,10-Dimethoxycanthin-6-one 155861-51-1 98%
    9,10-Dimethoxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 19.5 μM.
    9,10-Dimethoxycanthin-6-one
  • HY-N7183
    9-Hydroxycanthin-6-one 138544-91-9 98%
    9-Hydroxycanthin-6-one is an alkaloid compound. 9,10-Dimethoxycanthin-6-one exhibits NF-κB inhibitory effects with an IC50 of 3.8 μM.
    9-Hydroxycanthin-6-one
  • HY-N7218
    Lysolipin I 59113-57-4 98%
    Lysolipin I is a lipophilic antibiotic from Streptomyces violaceoniger. Lysolipin I is active against Gram-positive and Gramnegative bacteria.
    Lysolipin I
  • HY-N7312
    Ditryptophenaline 64947-43-9 98%
    Ditryptophenaline ((-)-Ditryptophenaline) is the metabolites of Aspergillus flavus. Ditryptophenaline inhibits substance P receptor and has anti-inflammatory activity.
    Ditryptophenaline
  • HY-N7329
    Corymbosin 18103-41-8 98%
    Corymbosin is a glucoside. Corymbosin can be isolated from the aerial parts of Ballota glandulosissima. Corymbosin also has antifungal flavonoid activity.
    Corymbosin
Cat. No. Product Name / Synonyms Application Reactivity