1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N4234
    Angelol K 169736-93-0 98%
    Angelol K is a natural product from Chinese angelica.
    Angelol K
  • HY-N4235
    Angelol B 83156-04-1 98%
    Angelol B is a coumarin isolated from the roots of Angelica pubescens f. biserrata, which is passive diffusion as the dominating process in Caco-2 cell monolayer model.
    Angelol B
  • HY-N4237
    Saikogenin D 5573-16-0 99.99%
    Saikogenin D is isolated from?Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca2+]i due to Ca2+ release from intracellular stores.
    Saikogenin D
  • HY-N4263
    5,6-Didehydroginsenoside Rd 1268459-68-2 98%
    5,6-Didehydroginsenoside Rd is a dammarane-type saponin isolated from the dried roots of Panax notoginseng.
    5,6-Didehydroginsenoside Rd
  • HY-N4264
    Vinaginsenoside R3 156012-92-9 98%
    Vinaginsenoside R3 is a saponin composition of roots of Panax ginseng. Ginsengs have been not only used as therapeutic agents with tonic, anti-fatigue, and anti-gastric ulcer effect but also marketed as dietary supplements and raw materials of health food.
    Vinaginsenoside R3
  • HY-N4278
    Huangjiangsu A 1026020-27-8 98%
    Huangjiangsu A, pseudoprotodioscin, methyl protobioside, protodioscin, and protodeltonin, isolated from D. villosa. Huangjiangsu A has hepatoprotective potential against H2O2-induced cytotoxicity and ROS generation and could be promising as potential therapeutic agents for liver diseases.
    Huangjiangsu A
  • HY-N4280
    7,8-Dimethoxycoumarin 2445-80-9 98%
    7,8-Dimethoxycoumarin (Daphnetin dimethyl ether) is a coumarin from Artemisia caruifolia.
    7,8-Dimethoxycoumarin
  • HY-N4298
    Epitheaflagallin 3-O-gallate 102067-92-5 98%
    Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.
    Epitheaflagallin 3-O-gallate
  • HY-N5031
    Mulberrofuran Q 101383-35-1 98%
    Mulberrofuran Q inhibits the formation of 12-hydroxy-5,8,10-heptadecatrienoic acid (HHT) and thromboxane B2 (cyclooxygenase products).
    Mulberrofuran Q
  • HY-N5045
    Jionoside A1 120444-60-2 98%
    Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H2O2-treated SH-SY5Y cells.
    Jionoside A1
  • HY-N5046
    27-O-Acetyl-withaferin A 1214886-35-7 98%
    27-O-Acetyl-withaferin A is found in Withania aristata.
    27-O-Acetyl-withaferin A
  • HY-N5051
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside 125225-63-0 98%
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside shows inhibitory activity of neutrophil respiratory burst stimulated by PMA(phorbol myristate acetate).
    25(S)-Ruscogenin-1-O-α-L-rhamnopyranosyl (1→2)-β-D-xylopyranoside
  • HY-N5054
    (R)-5,7-Dimethoxyflavanone 1277188-85-8 ≥99.0%
    (R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains. And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato.
    (R)-5,7-Dimethoxyflavanone
  • HY-N5067
    Rhodiocyanoside A 168433-86-1 98%
    Rhodiocyanoside A is found to show antiallergic activity in a passive cutaneous anaphylaxis test in rat.
    Rhodiocyanoside A
  • HY-N5076
    Picfeltarraenin IV 184288-35-5 98%
    Picfeltarraenin IV, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IV can be used for the treatment of herpes infections, cancer and inflammation.
    Picfeltarraenin IV
  • HY-N5089
    (+)-Balanophonin 215319-47-4 98%
    (+)-Balanophonin is a phenolic compound that could be isolated from Passiflora edulis. (+)-Balanophonin possesses anti-oxidant, anticholinesterase, anti-inflammatory, anticancer, and antineurodegenerative activities.
    (+)-Balanophonin
  • HY-N6032
    Esculentoside B 60820-94-2 98%
    Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity.
    Esculentoside B
  • HY-N6049
    Lup-20(29)-en-28-oic acid 848784-85-0 98%
    Lup-20(29)-en-28-oic acid, a triterpenoid saponins of Pulsatilla koreana Root, possesses anti-inflammatory and anti-tumor effect.
    Lup-20(29)-en-28-oic acid
  • HY-N6054
    Niranthin 50656-77-4 98%
    Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research.
    Niranthin
  • HY-N6245
    Daphylloside 14260-99-2 98%
    Daphylloside is an iridoid isolated from the aerial parts of Galium verum.
    Daphylloside
Cat. No. Product Name / Synonyms Application Reactivity