2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3508
    Hyponine D 259823-31-9 98%
    Hyponine D is an immunosuppressive sesquiterpene alkaloid that could be isolated from Tripterygium wilfordii.
    Hyponine D
  • HY-N3509
    Hyponine E 226975-99-1 98%
    Hyponine E, a macrocyclic sesquiterpene pyridine alkaloid that could be isolated from from Tripterygium hypoglaucum, possesses anti-inflammatory effects.
    Hyponine E
  • HY-N3510
    Peritassine A 262601-67-2 98%
    Peritassine A, an alkaloid that could be isolated from Tripterygium wilfordii Hook. f., possesses anti-HIV activity.
    Peritassine A
  • HY-N3524
    Calycanthoside 483-91-0 98%
    Calycanthoside is a natural compound isolated from Angelica tenuissima.
    Calycanthoside
  • HY-N3532
    Cannabisin F 163136-19-4 98%
    Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2.
    Cannabisin F
  • HY-N3552
    Catalposide 6736-85-2 ≥98.0%
    Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages.
    Catalposide
  • HY-N3587
    Cimiside B 152685-91-1
    Cimiside B is a glycoside alkaloid with anti-inflammatory activity.
    Cimiside B
  • HY-N3602
    Cleroindicin F 189264-47-9 98%
    Cleroindicin F ((-)-Rengyolone), a cleroindicin, is an antimicrobial agent. Cleroindicin F shows relatively high anticandidal activity against Candida strains with a MIC value down to 12.5 µg/mL.
    Cleroindicin F
  • HY-N3612
    Communic acid 2761-77-5 98%
    Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging.
    Communic acid
  • HY-N3625
    Coronalolic acid 268214-52-4 98%
    Coronalolic acid, extract from the apical bud of Gardenia sootepenesis Hutch, inhibits TNF-α-induced NF-κB activity and NO production.
    Coronalolic acid
  • HY-N3631
    Ethoxycoronarin D 138965-89-6 98%
    Ethoxycoronarin D is a labdane diterpenes compound isolated from rhizomes. Ethoxycoronarin D selectively inhibits COX-1 with an IC50 of 3.8 µM.
    Ethoxycoronarin D
  • HY-N3632
    Methoxycoronarin D 157528-81-9 98%
    Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-κB with an IC50 value of 7.3 μM. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 μM.
    Methoxycoronarin D
  • HY-N3667
    Cycloheterophyllin 36545-53-6 98%
    Cycloheterophyllin is a flavonoid, that can be isolated from Artocarpus communis and A. heterophyllus. Cycloheterophyllin shows antiinflammatory activity.
    Cycloheterophyllin
  • HY-N3674
    Dalbergioidin 30368-42-4 98%
    Dalbergioidin, a well-known anthocyanin, ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM.
    Dalbergioidin
  • HY-N3693
    De-4′-O-methylyangambin 149250-48-6 98%
    De-4’-O-methylyangambin is a lignan that can be isolated from Z. armatum. lignans are reported to has anti-inflammatory activity.
    De-4′-O-methylyangambin
  • HY-N3702
    Dehydroabietinol 3772-55-2 98%
    Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease.
    Dehydroabietinol
  • HY-N3716
    Dehydroglyasperin D 517885-72-2 98%
    Dehydroglyasperin D inhibits rat and human Aldose Reductase (AR) (IC50: 62.4 μM and 176.2 μM respectively). Dehydroglyasperin D has anti-obesity, antioxidant effects. Dehydroglyasperin D shows anti-inflammatory activity by inhibiting COX-2 expression and the MLK3 signaling pathway. Dehydroglyasperin D also inhibits melanin synthesis. Dehydroglyasperin D is a prenylated flavonoid that can be isolated from Glycyrrhiza uralensi.
    Dehydroglyasperin D
  • HY-N3760
    Dimeric coniferyl acetate 184046-40-0 98%
    Dimeric coniferyl acetate is a NO production inhibitor with an IC50 value 7.9 μM in BV-2 microglial cells.
    Dimeric coniferyl acetate
  • HY-N3769
    Dipterocarpol 471-69-2 98%
    Dipterocarpol is a dammarane-type triterpenoid. Dipterocarpol is substrate of the bacterial steroid-hydroxylase CYP106A2.
    Dipterocarpol
  • HY-N3788
    Dulcioic acid 78516-69-5 98%
    Dulcioic acid (compound 19) is a product isolated from Tripterygium wilfordii Hook f. Dulcioic acid shows a significant inhibitory effect on cytokine production.
    Dulcioic acid
Cat. No. Product Name / Synonyms Application Reactivity