1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N3226
    Myricananin A 1079941-35-7 98%
    Myricananin A is a colorless needle that has inhibitory effect on iNOS.
    Myricananin A
  • HY-N3229
    Mussaenoside 64421-27-8 98%
    Mussaenoside can be isolated from Veronica officinalis L.. Mussaenoside has anti-inflammatory and antioxidant activity.
    Mussaenoside
  • HY-N3230
    Murpanicin 88478-44-8 98%
    Murpanicin (murraxocin) is a coumarin that is a thermosensitive transient receptor potential vanilloid 2 (TRPV2) channel inhibitor. Murpanicin has significant anti-inflammatory and insecticidal effects.
    Murpanicin
  • HY-N3237
    Mulberrofuran H 89199-99-5 98%
    Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities.
    Mulberrofuran H
  • HY-N3246
    Morachalcone A 76472-88-3 98%
    Morachalcone A is a naturally-occurring aromatase inhibitor (IC50=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production.
    Morachalcone A
  • HY-N3248
    Momordicoside G 81371-54-2 98%
    Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury.
    Momordicoside G
  • HY-N3294
    Mesuol 16981-20-7 98%
    Mesuol, a natural product isolated from M. ferrea L. seed oil, has antioxidant and immunomodulatory effects.
    Mesuol
  • HY-N3295
    Mesuaxanthone A 3561-81-7 98%
    Mesuaxanthone A is a xanthone with anti-inflammatory activities. Mesuaxanthone A shows typical CNS depressant effects.
    Mesuaxanthone A
  • HY-N3296
    Meridinol 120051-54-9 98%
    Meridinol ((-)-Meridinol) shows antimicrobial activity against a wide range of gram-positive and gram-negative bacteria and fungi.
    Meridinol
  • HY-N3305
    Megastigm-7-ene-3,5,6,9-tetraol 680617-50-9 98%
    Megastigm-7-ene-3,5,6,9-tetraol (Megastigma-7-en-3,5,6,9-tetraol) is a diterpenoid analogue in the aerial parts of Isodon melissoides. Megastigm-7-ene-3,5,6,9-tetraol is also in Vigna luteola and has anti-inflammatory bioactivity.
    Megastigm-7-ene-3,5,6,9-tetraol
  • HY-N3315
    Massonianoside B 188300-19-8 98%
    Massonianoside B is an antioxidant, which can be isolated from Cedrus deodara pine needle. Massonianoside B exhibits radicals scavenging capacities, and restores CCL4-impaired activity of antioxidant enzymes.
    Massonianoside B
  • HY-N3323
    Mannioside A 1038922-95-0 98%
    Mannioside A is a steroidal saponin. Mannioside A is a nature product that could be isolated from Dracaena mannii. Mannioside A has anti-inflammatory effect.
    Mannioside A
  • HY-N3348
    Lyoniside 34425-25-7 98%
    Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC50 value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively.
    Lyoniside
  • HY-N3364
    Lucidone 19956-53-7 98%
    Lucidone, an anti-inflammatory agent that can be isolated from the fruit of Lindera erythrocarpa Makino. Lucidone inhibits LPS-induced NO and PGE2 production in RAW 264.7 mouse macrophages. Lucidone also decreases TNF-α secretion, iNOS and COX-2 expression. Lucidone prevents NF-κB translocation and inhibits JNK and p38MAPK signals. Lucidone also has inhibitory activity against Dengue virus (DENV) (EC50=25 μM).
    Lucidone
  • HY-N3380
    Linderaspirone A 1235126-46-1 98%
    Linderaspirone A is a natural compound that can be isolated from the roots of Lindera aggregate. Linderaspirone A shows significant inhibitory effects on the production of prostaglandin E2 (PGE2),TNF-α, and IL-6 .
    Linderaspirone A
  • HY-N3392
    Lethedoside A 221289-20-9 98%
    Lethedoside A is a natural flavonoid that shows inhibitory activity for LPS-induced NO production in RAW 264.7 cells.
    Lethedoside A
  • HY-N3408
    Lamiide 27856-54-8
    Lamiide, an orally active iridoid compound, can be found in Bouchea fluminensis leaves. Lamiide exhibits anti-inflammatory and anti-lipoperoxidative activity.
    Lamiide
  • HY-N3421
    Koaburaside 41653-73-0 98%
    Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase.
    Koaburaside
  • HY-N3424
    Kelampayoside A 87562-76-3 98%
    Kelampayoside A, a natural compound, shows an EC50 value of 35.7 µg/mL in DPPH assay (antioxidative activity).
    Kelampayoside A
  • HY-N3472
    Isomagnolone 155709-41-4 98%
    Isomagnolone is isolated from Illicium burmanicum and has anti-inflammatory activity.
    Isomagnolone
Cat. No. Product Name / Synonyms Application Reactivity