2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2715
    6-Methoxynaringenin 94942-49-1 98%
    6-Methoxynaringenin is a natural flavonoid that inhibits NO production with an IC50 of 25.8 μM.
    6-Methoxynaringenin
  • HY-N2838
    Alismol 87827-55-2 98%
    Alismol is a natural sesquiterpene. Alismol shows promising inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells.
    Alismol
  • HY-N2843
    α-Amyrin palmitate 22255-10-3 98%
    α-Amyrin palmitate is isolated from Santalum album (sandalwood). α-Amyrin palmitate can be used for the study of arthritis in vivo.
    α-Amyrin palmitate
  • HY-N2874
    Anhydroglycinol 67685-22-7 98%
    Anhydroglycinol is a phenolic compound that can be isolated from Lespedeza homoloba. Anhydroglycinol has strong antioxidative and antiallergic activity against lipid peroxidation in the rat.
    Anhydroglycinol
  • HY-N2920
    β-Amyrenonol 38242-02-3 98%
    β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids.
    β-Amyrenonol
  • HY-N2933
    Betulalbuside A 64776-96-1 98%
    Betulalbuside A is a monoterpene glucoside found in Viburnum lantana that has anti-inflammatory activity.
    Betulalbuside A
  • HY-N2941
    Bisandrographolide C 160498-02-2 98%
    Bisandrographolide C is an unusual dimer of ent-labdane diterpenoid isolated and identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels with Kd values of 289 and 341 μM respectively, and protects cardiomyocytes from hypoxia-reoxygenation injury.
    Bisandrographolide C
  • HY-N2958
    Braylin 6054-10-0 98%
    Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammatory and immunomodulation, which may serve as a potential target for the study of immunoinflammatory diseases.
    Braylin
  • HY-N2962
    Broussonin C 76045-49-3 98%
    Broussonin C is a competitive inhibitor of Tyrosinase that can be isolated from Broussonetia kazinoki. Broussonin C inhibits monophenolase and diphenolase with IC50s of 0.43 and 0.57 μM, respectively.
    Broussonin C
  • HY-N2965
    Bryonolic acid 24480-45-3 98%
    Bryonolic acid is an active triterpenoid compound with immunomodulatory, anti-inflammatory, antioxidant and anticancer activities.
    Bryonolic acid
  • HY-N2968
    Bullatantriol 99933-32-1 98%
    Bullatantriol ((+)?-?Bullatantriol) can be isolated from the roots of Homalomena aromatica. Bullatantriol can promote the proliferation and differentiation of osteoblasts. Bullatantriol also inhibits LPS-induced NO production in BV2 cells.
    Bullatantriol
  • HY-N2988
    Schisanwilsonin C 1181216-83-0 98%
    Schisanwilsonin C (Arisanschinin K) shows anti-HBV activity.
    Schisanwilsonin C
  • HY-N2989
    3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 168293-14-9 98%
    3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells.
    3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
  • HY-N2990
    16α-Hydroxydehydrotrametenolic acid 176390-66-2 98%
    16α-Hydroxydehydrotrametenolic acid is a triterpene Acid in fermented mycelia of edible fungus Poria cocos.
    16α-Hydroxydehydrotrametenolic acid
  • HY-N3003
    Darutigenol 5940-00-1 98%
    Darutigenol is an ent-pimarane-type diterpenoid isolated from Siegesbecikia orientalis L..
    Darutigenol
  • HY-N3030
    Sylvestroside I 71431-22-6 98%
    Sylvestroside I is an iridoid isolated from Acicarpha tribuloides.
    Sylvestroside I
  • HY-N3071
    Picrasidine I 100234-59-1 98%
    Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1.
    Picrasidine I
  • HY-N3114
    Panaxydiol 63910-76-9 98%
    Panaxydiol exhibits histamine-release inhibition activity. Panaxydiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Panaxydiol
  • HY-N3147
    Olean-12-ene-3,11-dione 2935-32-2 98%
    Olean-12-ene-3,11-dione is a natural product that can be isolated from Euonymus laxiflorus and Canarium zeylanicum. Olean-12-ene-3,11-dione has antiinflammatory activity.
    Olean-12-ene-3,11-dione
  • HY-N3180
    Norbraylin 60796-64-7 98%
    Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC50 value of 7.15 μM.
    Norbraylin
Cat. No. Product Name / Synonyms Application Reactivity