2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-D0038
    BTBCT 525560-81-0 98%
    BTBCT is mainly used as a label in time-resolved fluorescence immunoassays (TRFIA). The lower limit of detection for TSH TR-IFMA is 0.011 mIU/L in a 10 μl sample volume. The high fluorescence intensity and stability of BTBCT improves the sensitivity of the assay.
    BTBCT
  • HY-D1199
    Blue FPG-A trisodium 78617-94-4 98%
    Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2).
    Blue FPG-A trisodium
  • HY-D1274
    Sulfo-cyanine3 azide 1658416-54-6 98%
    Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Sulfo-cyanine3 azide
  • HY-D1286
    Serum CG probe 1 98%
    Serum CG probe 1 (formula (9)) is a compound for determining serum cholyglycine.
    Serum CG probe 1
  • HY-D1287
    Serum CG probe 2 98%
    Serum CG probe 2 (formula (15)) is a compound for determining serum cholyglycine.
    Serum CG probe 2
  • HY-D1782
    Selenomethylene blue 85670-01-5
    Selenomethylene blue is an antioxidant and anti-inflammatory agent. Selenomethylene blue effectively inhibits the inflammatory paw edema in rats.
    Selenomethylene blue
  • HY-D2094
    PerCP Maleimide 98%
    PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes.
    PerCP Maleimide
  • HY-D2279
    NFL-NH2 98%
    NFL-NH2 is a mitochondrial-targeted near-infrared ratiometric fluorescent probe. NFL-NH2 can rapidly detect NO levels associated with the inflammatory damage degree in rheumatoid arthritis (RA) mice models by ratiometric fluorescence imaging. The excitation wavelength and emission wavelength are 650 nm and 780 nm, respectively.
    NFL-NH2
  • HY-D2310
    CXCR2 Probe 1 98%
    CXCR2 Probe 1 (Compound [18F]16b) is a selective ligand for CXCR2 and is a radiotracer for PET imaging of neutrophils in inflammatory diseases.
    CXCR2 Probe 1
  • HY-D2333
    RhFNMB 98%
    RhFNMB is a dualchannel/localization single-molecule fluorescence probe for ATP and HOCl, with independent fluorescence responses in the light red channel with ATP (λex = 520 nm, λem = 586 nm) and deep red channel with HOCl (λex = 620 nm, λem = 688 nm).
    RhFNMB
  • HY-N0278
    Anemonin 508-44-1 98%
    Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases.
    Anemonin
  • HY-N0725
    Cucurbitacin S 60137-06-6 98%
    Cucurbitacin S is isolated from cucurbitaceae with anticancer and anti-inflammatory activities.
    Cucurbitacin S
  • HY-N0954
    (+)-Pinoresinol diacetate 32971-25-8 98%
    (+)-Pinoresinol diacetate is an antifungal agent that can be isolated from Sambucus williamsii.
    (+)-Pinoresinol diacetate
  • HY-N0983
    1,3,7-Trihydroxy-2-prenylxanthone 20245-39-0 98%
    1,3,7-Trihydroxy-2-prenylxanthone, a xanthone, shows weaker antibacterial activity. 1,3,7-Trihydroxy-2-prenylxanthone exhibits the MIC values of 6.25 mg/ml against VREs strains (E. faecalis, E. faecium, and E. gallinarum).
    1,3,7-Trihydroxy-2-prenylxanthone
  • HY-N0997
    (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one 1251830-57-5 98%
    (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC50 value of 8.93 μM.
    (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one
  • HY-N1006
    10-Hydroxyscandine 119188-47-5 98%
    10-Hydroxyscandine is an alkaloid from Melodinus tenuicaudatus. 10-Hydroxyscandine can be used for the research of hernia, dyspepsia, abdominal pain, and rheumatic heart.
    10-Hydroxyscandine
  • HY-N1037
    δ-Amyrenone 20248-08-2 ≥98.0%
    δ-Amyrenone (Delta-Amyrone) is a pentacyclic triterpene compound from S. lineare, with anti-inflammatory effects.
    δ-Amyrenone
  • HY-N1065
    Xanthoxyletin 84-99-1 98%
    Xanthoxyletin is a coumarin that can be isolated from Genus Zanthoxylum and Clausena. Xanthoxyletin has antioxidant and anti-inflammatory activities. Xanthoxyletin shows cytotoxic effects to cancer cells, and induces apoptosis and necrosis. Xanthoxyletin can be used for the research of cancer and inflammation.
    Xanthoxyletin
  • HY-N1069
    Wittifuran X 1309478-07-6 98%
    Wittifuran X is a 2-arylbenzofuran derivative, which can be isolated from the stem bark of Morus wittiorum.
    Wittifuran X
  • HY-N1080
    Vitexdoin A 1186021-77-1 98%
    Vitexdoin A is a nitric oxide scavenging lignin. Vitexdoin A inhibits NO production with an IC50 of 0.38 μM in LPS (HY-D1056)-stimulated RAW 264.7 cells.
    Vitexdoin A
Cat. No. Product Name / Synonyms Application Reactivity