2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-138023
    Leucomycin A4 18361-46-1 98%
    Leucomycin A4 is a macrolide antibiotic that can be extracted from S. kitasatoensis. Leucomycin A4 inhibits a variety of bacteria, including S. aureus, B. subtilis, C. diphtheriae, N. gonorrhoeae, and H. influenzae (MICs = 0.15, 1.25, 0.15, 0.6, and 0.15 µg/ml, respectively).
    Leucomycin A4
  • HY-138035
    Tenellin 53823-15-7 98%
    Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 μg/mL.1 Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of- 4.84 and 11.95 μM, respectively.
    Tenellin
  • HY-138100
    Hyalodendrin 51920-94-6 98%
    Hyalodendrin ((+)-Hyalodendrin) is a fungal growth inhibitor with inhibitory activity against wood decay fungi. Hyalodendrin has low phytotoxicity, with an acute toxicity (LD50) of 75 mg/kg in mice.
    Hyalodendrin
  • HY-138179
    7-APRA 120709-09-3
    7-APRA is a semi-synthetic intermediate of cephalosporin antibiotics. 7-APRA has antibacterial activity and is mainly used in the synthesis of other Cefaclor (HY-B0198) and Cefprozil (HY-B0458A).
    7-APRA
  • HY-138194
    Destomycin B 11005-98-4 98%
    Destomycin B (A-16316-C) is an antibiotic, and is active against fungi. Destomycin B also has anthelmintic activity.
    Destomycin B
  • HY-138210
    N,O-Diacetyltyramine 14383-56-3 98%
    N,O-Diacetyltyramine is a compound with antibacterial activity and cytotoxicity that can be isolated from the actinomycete Pseudonocardia endophytica VUK-10. N,O-Diacetyltyramine has antibacterial activity against Gram-positive and Gram-negative bacteria and fungi. N,O-Diacetyltyramine is cytotoxic to MDA-MB-231, HeLa, MCF-7 and OAW-42 cells.
    N,O-Diacetyltyramine
  • HY-138223
    6-Prenylindole 23158-16-9 98%
    6-Prenylindole is an antifungal agent that can be isolated from Streptomyces.
    6-Prenylindole
  • HY-138269
    Barzuxetan 157380-45-5
    Barzuxetan can be used for cancer diseases research.
    Barzuxetan
  • HY-13832R
    Atovaquone (Standard) 95233-18-4
    Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and  P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia.
    Atovaquone (Standard)
  • HY-13832S
    Atovaquone-d4 2070015-14-2 99.8%
    Atovaquone-d4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia[1].
    Atovaquone-d4
  • HY-138573
    N-Acetyl Adamantamine 880-52-4 98%
    N-Acetyl Adamantamine (1-Acetamidoadamantane) is a major metabolite of Amantadine (HY-B0402)[1].
    N-Acetyl Adamantamine
  • HY-138796
    Griseolutein A 573-84-2 98%
    Griseolutein A shows activitiy against Gram-positive and negative bacteria.
    Griseolutein A
  • HY-138797
    Griseolutein B 2072-68-6 98%
    Griseolutein B shows activitiy against Gram-positive and negative bacteria.
    Griseolutein B
  • HY-138812
    Antileishmanial agent-28 1135272-09-1 98%
    Antileishmanial agent-28 (Compd 12) is an antileishmanial agent, with EC50 values of 1.5 μM (L.donovani), 13 μM (L.amazonensis) and 18 μM (J774A.1), respectively.
    Antileishmanial agent-28
  • HY-138870
    Enzyme-IN-3 disodium 122855-18-9 98%
    Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Enzyme-IN-3 disodium has antibacterial activity.
    Enzyme-IN-3 disodium
  • HY-13910B
    Tenofovir maleate 1236287-04-9 98%
    Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
    Tenofovir maleate
  • HY-139111
    Oxocarbazate 1014405-03-8 98%
    Oxocarbazate is an inhibitor of human cathepsin L with the IC50 values of 6.9 nM (human Cathepsin L,0 h) 0.4 nM ((human Cathepsin L,4 h) and 5.07 μM (human cathepsin B), respectively. Oxocarbazate blockes both SARS-CoV (IC50 = 273 nM) and Ebola virus (IC50 = 193 nM) entry into 293T cells.
    Oxocarbazate
  • HY-139223
    pEBOV-IN-1 1252187-41-9 98%
    pEBOV-IN-1 (Comp 2) is a pEBOV inhibitor, with an EC50 value of 0.38 μM. pEBOV: pseudotyped Ebola virus.
    pEBOV-IN-1
  • HY-139355
    (S)-GS-621763 2563617-99-0 98%
    (S)-GS-621763 is the S-enantiomer of GS-621763 (HY-145119). GS-621763 is an orally active prodrug form of GS-443902 (HY-126303) that inhibits SARS-CoV-2.
    (S)-GS-621763
  • HY-139794
    SDZ283-910 164514-54-9 98%
    SDZ283-910 is a potent human immunodeficiency virus type-1 (HIV-1) protease inhibitor.
    SDZ283-910
Cat. No. Product Name / Synonyms Application Reactivity