2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-10108R
    LY294002 (Standard) 154447-36-6 98%
    LY294002 (Standard) is the analytical standard of LY294002. This product is intended for research and analytical applications. LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ and PI3Kβ, respectively. LY294002 also inhibits CK2 with an IC50 of 98 nM. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4?μM. LY294002 is an apoptosis activator.
    LY294002 (Standard)
  • HY-101424
    2-Chloro-N-(2-methyl-4-bromophenyl)acetamide 96686-51-0 98%
    2-Chloro-N-(2-methyl-4-bromophenyl)acetamide is an antifungal compound.
    2-Chloro-N-(2-methyl-4-bromophenyl)acetamide
  • HY-101575
    Acetylazide 3590-05-4 98%
    Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
    Acetylazide
  • HY-101590
    Symetine 15599-45-8 98%
    Symetine is an antiparasitic and antispirochete agent.
    Symetine
  • HY-101593
    Fibracillin 51154-48-4 98%
    Fibracillin is a penicillin antibiotic.
    Fibracillin
  • HY-101651
    WQ 2743 189280-13-5 98%
    WQ 2743 is a potent antimicrobial agent.
    WQ 2743
  • HY-101739
    Amcinafal 3924-70-7 98%
    Amcinafal is an active diol, used against virus replication and interferon production.
    Amcinafal
  • HY-101818
    PNU288034 383199-88-0 98%
    PNU288034 is a potent oxazolidinone antibiotic.
    PNU288034
  • HY-101829
    Sulfaproxiline 116-42-7 99.37%
    Sulfaproxiline is a synthetic antimicrobial agent that is sulfonamide.
    Sulfaproxiline
  • HY-101967
    GSK299423 1352149-24-6 98%
    GSK 299423 is an antibiotic agent.GSK299423 shows potent inhibition of supercoiling by DNA gyrase from S. aureus(IC50=14 nM）and Escherichia coli(IC50=100 nM.
    GSK299423
  • HY-102008
    LBM-415 478913-91-6 98%
    LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy.
    LBM-415
  • HY-10234S
    Saracatinib-d3 2200301-36-4 98%
    Saracatinib-d3 (AZD0530-d3) (ZG5129) is the deuterium-labeled analog of Saracatinib (HY-10234). Saracatinib-d3 is an inhibitor of the Src kinase, which can inhibit severe sepsis caused by bacterial or various microbial infections.
    Saracatinib-d3
  • HY-10237R
    Boceprevir (Standard) 394730-60-0
    Boceprevir (Standard) is the analytical standard of Boceprevir. This product is intended for research and analytical applications. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay. Boceprevir inhibits SARS-CoV-2 3CLpro activity.
    Boceprevir (Standard)
  • HY-10240R
    Mericitabine (Standard) 940908-79-2 98%
    Mericitabine (Standard) is the analytical standard of Mericitabine. This product is intended for research and analytical applications. Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
    Mericitabine (Standard)
  • HY-10300R
    Narlaprevir (Standard) 865466-24-6 98%
    Narlaprevir (Standard) is the analytical standard of Narlaprevir. This product is intended for research and analytical applications. Narlaprevir (SCH 900518) is a selective and orally bioavailable NS3 protease inhibitor with a Ki value of 6 nM and an EC90 value of 40 nM. Narlaprevir also inhibits the HCV nonstructural protein 3 serine protease. Narlaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 2.3 μM.
    Narlaprevir (Standard)
  • HY-103365
    BX-513 hydrochloride 1216540-18-9 98%
    BX-513 hydrochloride (VUF 2274 hydrochloride)is a novel inverse agonists acting on human cytomegalovirus (HCMV)-encoded receptor US28 with the IC50 of 4.9 μM. BX-513 hydrochloride can be used for study of viral infection.
    BX-513 hydrochloride
  • HY-103658
    Myramistin 15809-19-5 98%
    Myramistin (Miramistin) is an antibacterial agent targeting bacterial cell membrane. Myramistin can bind to the negatively charged surface of bacteria through its cationic properties, disrupt the integrity of the bacterial cell membrane, inhibit bacterial metabolism and growth, and induce cell death, thus exerting antibacterial activity.
    Myramistin
  • HY-10367R
    Canertinib (Standard) 267243-28-7 98%
    Canertinib (Standard) is the analytical standard of Canertinib. This product is intended for research and analytical applications. Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice.
    Canertinib (Standard)
  • HY-10392S
    Sutezolid-13C4 98%
    Sutezolid-13C4 (PNU-100480-13C4) is 13C labeled Sutezolid. Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria, and is used for the research of drug-resistant tuberculosis.
    Sutezolid-13C4
  • HY-10396R
    Emricasan (Standard) 254750-02-2 98%
    Emricasan (Standard) is the analytical standard of Emricasan. This product is intended for research and analytical applications. Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors.
    Emricasan (Standard)
Cat. No. Product Name / Synonyms Application Reactivity