2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W749867
    Ca(II)-EDTA disodium dihydrate 6766-87-6
    CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis. CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning.
    Ca(II)-EDTA disodium dihydrate
  • HY-W790014
    Z-FG-NHO-BzOME 180313-86-4 98.14%
    Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain.
    Z-FG-NHO-BzOME
  • HY-W016819B
    5-Fluoroorotic acid monohydrate 220141-70-8 ≥98.0%
    5-Fluoroorotic acid monohydrate is the monohydrate salt form of 5-Fluoroorotic acid (HY-W016819). 5-Fluoroorotic acid monohydrate is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid monohydrate exhibits antimalarial activity.
    5-Fluoroorotic acid monohydrate
  • HY-15975
    GNF179 1261114-01-5 98.17%
    GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active.
    GNF179
  • HY-16102
    Bismuth subcitrate potassium 880149-29-1 ≥99.0%
    Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis.
    Bismuth subcitrate potassium
  • HY-18601
    (±)-BI-D 1416258-16-6 98.06%
    (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.
    (±)-BI-D
  • HY-21745
    MurA-IN-4 318280-69-2 ≥98.0%
    MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis.
    MurA-IN-4
  • HY-79635
    Methyl indole-3-carboxylate 942-24-5 99.89%
    Methyl indole-3-carboxylate is a natural product isolated from Sorangium cellulosum strain Soce895. Methyl indole-3-carboxylate shows a weak activity against the Gram-positive Nocardia sp with a MIC value of 33.33 μg/mL.
    Methyl indole-3-carboxylate
  • HY-B0187
    Doripenem 148016-81-3 99.94%
    Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria.
    Doripenem
  • HY-B0894
    Resorcinol monoacetate 102-29-4
    Resorcinol monoacetate (Acetylresorcinol) is a derivative of Resorcinol (HY-B0907). Resorcinol monoacetate can be used in research of skin infections such as acne, seborrheic dermatitis and tinea pedis.
    Resorcinol monoacetate
  • HY-B0930
    Efloxate 119-41-5 99.73%
    Efloxate (Angorlisin) is a vasodilator used in the research of chronic coronary insufficiency and angina pectoris. Efloxate binds to Staphylococcus aureus sortase A.
    Efloxate
  • HY-B1093
    Fenchlorphos 299-84-3 99.87%
    Fenchlorphos, an organophosphate, is an insecticide. Fenchlorphos is an inhibitor of the enzyme acetylcholinesterase (AChE). Fenchlorphos is able to cause mitochondrial dysfunction.
    Fenchlorphos
  • HY-B1111
    Amitraz 33089-61-1
    Amitraz is a non-systemic acaricide and insecticide with alpha-adrenergic agonist activity that interacts with octopamine receptors in the central nervous system and inhibits monoamine oxidase and prostaglandin synthesis.
    Amitraz
  • HY-B1166
    Cefamandole nafate 42540-40-9
    Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic.
    Cefamandole nafate
  • HY-B1177
    Crotamiton 483-63-6
    Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic.
    Crotamiton
  • HY-B1466
    Mezlocillin sodium 42057-22-7 98.06%
    Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research.
    Mezlocillin sodium
  • HY-B1629
    Dichlorodiphenylmethane 2051-90-3
    Dichlorodiphenylmethane is a drug intermediate, which is widely used in the fields of pesticide, dye and medicine.
    Dichlorodiphenylmethane
  • HY-B1703
    Nifursol 16915-70-1 98.17%
    Nifursol is an orally active veterinary antibiotic. Nifursol inhibits Histomonas meleagridis. Nifursol prevents histomoniasis in turkeys. Nifursol is widely used in studies of Escherichia coli gastroenteritis in Salmonella-infected poultry and aquatic animals.
    Nifursol
  • HY-B1870
    Metaldehyde 108-62-3 ≥98.0%
    Metaldehyde is a commonly used pesticide for mollusks such as slugs and snails.
    Metaldehyde
  • HY-B2015
    Carbosulfan 55285-14-8 ≥98.0%
    Carbosulfan inhibited relatively potently CYP3A4 and moderately CYP1A1/2 and CYP2C19 in pooled HLM (human livers).
    Carbosulfan
Cat. No. Product Name / Synonyms Application Reactivity