2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0875
    Cefmenoxime hydrochloride 75738-58-8 99.29%
    Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.
    Cefmenoxime hydrochloride
  • HY-B1414
    Chloroxylenol 88-04-0 99.24%
    Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses.
    Chloroxylenol
  • HY-B1437
    Acetarsol 97-44-9 99.87%
    Acetarsol (Stovarsol) is a potent and orally active anti-infective agent. Acetarsol shows anti-parasite activity. Acetarsol has the potential for the research of proctitis.
    Acetarsol
  • HY-B1537
    Azaribine 2169-64-4 ≥99.0%
    Azaribine (2',3',5'-Tri-O-acetyl-6-azauridine) is a potent orotidine monophosphate decarboxylase (OMPD) inhibitor. Azaribine is an antiviral inhibitor of several RNA viruses and inhibits viral genome replication and gene transcription. Azaribine shows broad-spectrum antiviral activity (EC50=3.80 nM-1.73 μM against influenza A and B viruses; EC50=1.62 μM against ZIKV Paraiba). Azaribine, a triacetate salt of Azauridine, has the potential for psoriasis research.
    Azaribine
  • HY-B1784
    Sulfisomidin 515-64-0 99.75%
    Sulfisomidin (Sulfaisodimidine) is an orally active short-acting sulfonamide antibacterial. Sulfisomidin can be used for the research of lower urinary tract infections.
    Sulfisomidin
  • HY-B1881
    Pirimiphos-methyl 29232-93-7 98.00%
    Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
    Pirimiphos-methyl
  • HY-D0128
    4-Methylherniarin 2555-28-4 98.39%
    4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml.
    4-Methylherniarin
  • HY-D0948
    Celestine Blue 1562-90-9
    Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen.
    Celestine Blue
  • HY-D1460
    Fluorescein Di-β-D-Glucuronide 134869-04-8
    Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies.
    Fluorescein Di-β-D-Glucuronide
  • HY-I0501
    2'-Aminoacetophenone 551-93-9 99.82%
    2'-Aminoacetophenone is an orally active inducer of apoptosis and respiratory biomarker. 2'-Aminoacetophenone can be used to detect Pseudomonas aeruginosa infections in the lungs of cystic fibrosis patients. 2'-Aminoacetophenone can inhibit the protein levels of LC3BII and p62 in macrophages infected with pqsA or mvfR and regulate autophagy. 2'-Aminoacetophenone can disrupt mitochondrial function by inducing oxidative stress and apoptosis signaling, leading to dysfunction in mouse skeletal muscle.
    2'-Aminoacetophenone
  • HY-N0381
    Maackiain 19908-48-6 98.47%
    Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of  21.95 µg/mL. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells.
    Maackiain
  • HY-N0772
    Isomangiferin 24699-16-9 99.82%
    Isomangiferin, a natural product, is reported to have antiviral activity.
    Isomangiferin
  • HY-N1096
    Veratraldehyde 120-14-9 ≥98.0%
    Veratraldehyde is an orally active aromatic compound and antibacterial agent. Veratraldehyde can be isolated from essential oils of plants such as peppermint and ginger. Veratraldehyde targets the PilY1 protein. Veratraldehyde has antibacterial activity against Pseudomonas aeruginosa. Veratraldehyde has a repellent effect against mosquitoes and ticks. Veratraldehyde can be used as a flavoring agent.
    Veratraldehyde
  • HY-N1136
    (+)-Totarol 511-15-9 98.46%
    (+)-Totarol is a diterpenoid compound isolated from Podocarpus spp.. (+)-Totarol is a potent antioxidant and antibacterial agent.
    (+)-Totarol
  • HY-N1910
    4'-O-Methylbavachalcone 20784-60-5 ≥99.0%
    4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM.
    4'-O-Methylbavachalcone
  • HY-N1927
    Menisdaurin 67765-58-6 ≥98.0%
    Menisdaurin is a cyanogenetic glucoside isolated from Flueggea virosa.
    Menisdaurin
  • HY-N2061
    Lindenenol 26146-27-0 99.85%
    Lindenenol is isolated from Radix linderae, with antioxidant and antibacterial activities.
    Lindenenol
  • HY-N2216
    Polygalasaponin XXXI 79103-90-5
    Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection.
    Polygalasaponin XXXI
  • HY-N2224
    Guaijaverin 22255-13-6 99.79%
    Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities.
    Guaijaverin
  • HY-N2795
    9-Hydroxycalabaxanthone 35349-68-9 99.14%
    9-Hydroxycalabaxanthone (Xanthone I) is a known xanthone isolated from Garcinia mangostana Linn. 9-Hydroxycalabaxanthone has quorum-sensing inhibitory, anti-microbial, and anti-malarial activities (IC50=1.2-1.5 μM).
    9-Hydroxycalabaxanthone
Cat. No. Product Name / Synonyms Application Reactivity