2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0535S
    Ethambutol-d4 1129526-19-7 98.12%
    Ethambutol-d4 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
    Ethambutol-d4
  • HY-12480
    Lanopepden 1152107-25-9 98.62%
    Lanopepden (GSK 1322322) is a peptidyl peptidase (PDF) inhibitor. Lanopepden inhibits PDF activity, preventing bacterial protein synthesis, thereby exerting antibacterial activity. Lanopepden is primarily effective against Gram-positive bacteria. Lanopepden is used in the study of acute bacterial skin and skin structure infections.
    Lanopepden
  • HY-12954
    PTACH 848354-66-5 99.65%
    PTACH (NCH-51) is a potent HDAC inhibitor with IC50s of 48 nM, 32 nM, and 41 nM for HDAC1, HDAC4, and HDAC6, respectively. PTACH exerts potent growth inhibition against various cancer cells (EC50s of 1.1-9.1 μM) .
    PTACH
  • HY-14987
    AX20017 329221-38-7 99.69%
    AX20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
    AX20017
  • HY-16487
    Temafloxacin 108319-06-8 99.65%
    Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections.
    Temafloxacin
  • HY-16721
    Cyclopropavir 632325-71-4 ≥98.0%
    Cyclopropavir (Filociclovir) is an orally active and broad-spectrum anti-herpesvirus compound. Cyclopropavir inhibits UL97 kinase activity. Cyclopropavir has antiviral activity against HCMV, MCMV, and HAdV6 viruses.
    Cyclopropavir
  • HY-16779
    Fosravuconazole 351227-64-0 99.86%
    Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research.
    Fosravuconazole
  • HY-16784
    Samatasvir 1312547-19-5 99.39%
    Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC50s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons.
    Samatasvir
  • HY-18563
    4-Phenoxybenzylamine 107622-80-0
    4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a.
    4-Phenoxybenzylamine
  • HY-19285
    Sulfaclozine 102-65-8 ≥99.0%
    Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine
  • HY-19364
    Ferroquine 185055-67-8 99.68%
    Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane.
    Ferroquine
  • HY-19827
    Aeroplysinin 1 28656-91-9
    Aeroplysinin 1 ((+)-Aeroplysinin-1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram-positive bacteria and exerts antiviral activity against HIV-1 (IC50=14.6 μM). Aeroplysinin 1 has anti-inflammatory, anti-angiogenic and anti-tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells.
    Aeroplysinin 1
  • HY-20349
    Monobehenin 30233-64-8
    Monobehenin, an bacterial biofilm formation inhibitor, has strong inhibitory activity toward bacterial biofilm formation of S. mutans, X. oryzae, and Y. enterocolitica in a strain specific manner.
    Monobehenin
  • HY-43575
    Oseltamivir-acetate 1191921-01-3 ≥98.0%
    Oseltamivir-acetate is an impurity of Oseltamivir. Oseltamivir is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
    Oseltamivir-acetate
  • HY-44358
    Remdesivir nucleoside monophosphate 1911578-74-9 99.98%
    Remdesivir nucleoside monophosphate is a metabolite of Remdesivir. Remdesivir is a nucleoside analogue with effective antiviral activity against SARS-CoV and MERS-CoV.
    Remdesivir nucleoside monophosphate
  • HY-75828
    Dibenzylideneacetone 538-58-9 99.71%
    Dibenzylideneacetone (Dibenzalacetone) is a potent inhibitor of chitinase with an IC50 value of 13.10 μM. The MIC value of Dibenzylideneacetone against Botrytis cinerea is 32 μg/mL, and the EC50 values for inhibiting mycelium growth and spore germination are 16.29 and 14.64 μg/mL, respectively. Dibenzylideneacetone can be used in research on fruit and vegetable preservatives.
    Dibenzylideneacetone
  • HY-76293
    I2906 331963-29-2 99.92%
    I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.
    I2906
  • HY-B0055
    Azulene 275-51-4 ≥98.0%
    Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry.
    Azulene
  • HY-B0213
    Sulfameter 651-06-9 99.94%
    Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections.
    Sulfameter
  • HY-B0755
    Etimicin sulfate 362045-44-1 99.59%
    Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.
    Etimicin sulfate
Cat. No. Product Name / Synonyms Application Reactivity