2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0854
    Alisol F 155521-45-2 ≥99.0%
    Alisol F is a triterpene isolated from Alisma orinentale, has immunosuppressive and anti-virus functions. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the HepG2.2.15 cell line with an IC50 of 0.6 μM.
    Alisol F
  • HY-N0903
    Dihydrochelerythrine 6880-91-7 99.39%
    Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.
    Dihydrochelerythrine
  • HY-P5589
    Plantaricin A 131463-18-8 99.45%
    Plantaricin A is an antimicrobial peptide derived from LactobacifZus plantarum against bacteria.
    Plantaricin A
  • HY-107483
    Cambendazole 26097-80-3 98.83%
    Cambendazole is one of the most effective agents for the research of human strongyloidiasis and .
    Cambendazole
  • HY-120097
    R-10015 2097938-51-5 99.72%
    R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.
    R-10015
  • HY-126818
    Desfuroylceftiofur 120882-22-6
    Desfuroylceftiofur is an active metabolite of Ceftiofur which is a broad-spectrum cephalosporin antibiotic. Desfuroylceftiofur is active against gram-positive and gram-negative bacteria.
    Desfuroylceftiofur
  • HY-132823
    Ledaborbactam 1842397-36-7 99.12%
    Iedaborbactam (VNRX-5236), as a β-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections.
    Ledaborbactam
  • HY-134891
    HMBPP lithium 396726-03-7
    HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos.
    HMBPP lithium
  • HY-139663
    IHVR-17028 1428247-78-2 99.61%
    IHVR-17028 is a potent and broad-spectrum antiviral agent. IHVR-17028 exhibits antiviral activity against BVDV, TCRV and DENV with EC50 values of 0.4 μM, 0.26 μM, 0.3 μM, respectively. IHVR-17028 is a potent ER α-glucosidase I inhibitor with an IC50 of 0.24 μM. IHVR-17028 can be used for infectious diseases research.
    IHVR-17028
  • HY-147241
    Alpibectir 2285440-39-1 99.81%
    Alpibectir is an antibacterial agent.
    Alpibectir
  • HY-148493
    MK-3402 2058151-78-1 99.96%
    MK-3402 (Compound303) is a metallo-beta-lactamase inhibitor, with IC50 values of 0.53, 0.25 and 0.169 nM against IMP-1, NDM-1, and VIM-1, respectively. MK-3402 can be used in bacterial research and shows a synergistic effect when used in combination with beta-lactam antibiotics.
    MK-3402
  • HY-15602B
    Ledipasvir D-tartrate 1502654-87-6 98.76%
    Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
    Ledipasvir D-tartrate
  • HY-161762
    RA-0002034 3038542-51-4 99.48%
    RA-0002034 is a Chikungunya virus (CHIKV) nsP2 protease inhibitor with an IC50 of 58 nM. RA-0002034 covalently modifies the catalytic cysteine in a site-specific manner.
    RA-0002034
  • HY-B0215A
    Acetylcysteine (extracted from plants) 616-91-1 100.45%
    Acetylcysteine (N-Acetylcysteine) extracted from plants is derived from plants and is an antioxidant and mucolytic agent that enhances the reserve of free radical scavengers in cells. It has been reported to prevent neuronal apoptosis while inducing apoptosis in smooth muscle cells. In addition, it inhibits HIV replication and serves as a substrate for microsomal glutathione transferase. This endogenous aminothiol is found in human plasma and urine and is commonly used as a mucolytic agent in clinical settings, usually administered by inhalation.
    Acetylcysteine (extracted from plants)
  • HY-B0215S
    Acetylcysteine-d3 131685-11-5
    Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.
    Acetylcysteine-d3
  • HY-B0239R
    Chloramphenicol (Standard) 56-75-7
    Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research.
    Chloramphenicol (Standard)
  • HY-N0113B
    Hordenine hydrochloride 6027-23-2 99.82%
    Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.
    Hordenine hydrochloride
  • HY-N1214R
    Squalene (Standard) 111-02-4
    Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity.
    Squalene (Standard)
  • HY-N12851
    4-OHE 2492-43-5
    4-OHE ((E)-4-Oxo-2-hexenal) is a mutagen formed by the peroxidation of omega-3 fats. 4-OHE has antibacterial activity.
    4-OHE
  • HY-U00092
    BAY-Y 3118 151213-16-0 99.22%
    BAY-Y 3118 is a new chlorofluoroquinolone with antimicrobial activity.
    BAY-Y 3118
Cat. No. Product Name / Synonyms Application Reactivity