2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0490R
    Hygromycin B (Standard) 31282-04-9 99.85%
    Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
    Hygromycin B (Standard)
  • HY-B1369R
    Imipenem monohydrate (Standard) 74431-23-5 99.52%
    Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections.
    Imipenem monohydrate (Standard)
  • HY-N0709R
    Coumarin (Standard) 91-64-5 99.96%
    Coumarin (Standard) is the analytical standard of Coumarin. This product is intended for research and analytical applications. Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity.
    Coumarin (Standard)
  • HY-N10544
    δ-Cadinene 483-76-1
    δ-Cadinene ((+)-δ-Cadinene) is a sesquiterpene in essential oils. δ-Cadinene shows antiproliferative and pro-apoptotic effects on human ovary cancer (OVCAR-3) cells. δ-Cadinene has trichomonacidal, antimicrobial, antifungal and anticancer properties.
    δ-Cadinene
  • HY-N1214R
    Squalene (Standard) 111-02-4
    Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity.
    Squalene (Standard)
  • HY-147097A
    EDA-DA TFA 87156-01-2
    EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    EDA-DA TFA
  • HY-N0097S3
    Guanosine-15N5 99.60%
    Guanosine-15N5 is the 15N labeled Guanosine. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity.
    Guanosine-15N5
  • HY-P990208
    Anti-Mouse IL-9 Antibody (9C1)
    Anti-Mouse IL-9 Antibody (9C1) is an anti-mouse IL-9 IgG2a monoclonal antibody. Anti-Mouse IL-9 Antibody (9C1) can reduce the activation of NF-κB signaling pathway and decrease the infiltration of inflammatory cells. Anti-Mouse IL-9 Antibody (9C1) effectively reduces Th9 cell-mediated allergic reactions and anti-tumor effects. Anti-Mouse IL-9 Antibody (9C1) can be used for researches on inflammation, infection conditions and cancer such as parasitic infections, allergic reactions, breast cancer and osteosarcoma.
    Anti-Mouse IL-9 Antibody (9C1)
  • HY-W003943
    6-Hydroxypyridin-3-ylboronic acid 903899-13-8
    6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors.
    6-Hydroxypyridin-3-ylboronic acid
  • HY-W004294
    1-Tetradecanol 112-72-1 99.34%
    1-Tetradecanol is a straight-chain saturated fatty alcohol and antibacterial agent. 1-Tetradecanol can be isolated from Myristica fragrans. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity.
    1-Tetradecanol
  • HY-W004570
    5-Nitro-1,10-phenanthroline 4199-88-6 99.88%
    5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells.
    5-Nitro-1,10-phenanthroline
  • HY-W006672
    Dibenzo[b,e]oxepin-11(6H)-one 4504-87-4
    Dibenzo[b,e]oxepin-11(6H)-one (Compound 1a) is a dibenzoxepinone derivative that exhibits significant antiparasitic activity.
    Dibenzo[b,e]oxepin-11(6H)-one
  • HY-W015820
    Phthalide 87-41-2 99.94%
    Phthalide is a chemical scaffold. Phthalide can be used to synthesize a variety of phthalide derivatives including anti-inflammatory agent, antimicrobial, antioxidant and blood-tumor barrier modulators.
    Phthalide
  • HY-W041343
    4-Benzoylbenzoic acid 611-95-0 98.95%
    4-(Phenylcarbonyl)benzoic acid is a photooxidant. Upon light activation, 4-(Phenylcarbonyl)benzoic acid forms an electrophilic aromatic ketone that acts as an oxidant in organic synthesis or biological systems. 4-(Phenylcarbonyl)benzoic acid has been used in the study of amino acid oxidation, as well as the synthesis of photoactivated antibacterial and antiviral compounds123.
    4-Benzoylbenzoic acid
  • HY-W054064
    6-Chloro-7-deazapurine-β-D-riboside 16754-80-6
    6-Chloro-7-deazapurine-β-D-riboside, a nucleoside derivative, exerts antifungal effects. 6-Chloro-7-deazapurine-β-D-riboside shows activity against plant pathogenic fungi.
    6-Chloro-7-deazapurine-β-D-riboside
  • HY-W150677
    BioA-IN-1 77820-11-2 99.24%
    BioA-IN-1 (Compound 15) is an inhibitor of BioA, a key enzyme in the biotin synthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. BioA-IN-1 exhibits antibacterial activity but has no cytotoxicity.
    BioA-IN-1
  • HY-128554S1
    N-Desethyl amodiaquine-d5 dihydrochloride 1216894-33-5 98.76%
    N-Desethyl amodiaquine-d5 dihydrochloride is the deuterium labeled N-Desethyl amodiaquine dihydrochloride. N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively.
    N-Desethyl amodiaquine-d5 dihydrochloride
  • HY-B1773AS3
    Sodium propionate-13C3 152571-51-2
    Sodium propionate-13C-3 is the 13C-labeled Propionate sodium (HY-B1773A). Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease.
    Sodium propionate-13C3
  • HY-B1210
    Pipemidic acid 51940-44-4 98.0%
    Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections.
    Pipemidic acid
  • HY-10852
    Arterolane 664338-39-0 98.0%
    Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
    Arterolane
Cat. No. Product Name / Synonyms Application Reactivity