2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P4086
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) 1678417-57-6 98.00%
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R), a chimeric peptide consisting of 29 amino acids, is synthesized by adding nona-arginine motif to the carboxy terminus of RVG (rabies virus glycoprotein). Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R) is positively charged and able to bind negatively charged nucleic acids via charge interaction.
    Chimeric Rabies Virus Glycoprotein Fragment (RVG-9R)
  • HY-100176
    PF-4878691 532959-63-0 99.89%
    PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer.
    PF-4878691
  • HY-100956
    Flurofamide 70788-28-2
    Flurofamide is a potent bacterial urease inhibitor with potential in the treatment of infection induced urinary stones.
    Flurofamide
  • HY-103081
    β-Glucuronidase-IN-1 484006-66-8 99.05%
    β-Glucuronidase-IN-1 is a potent, selective, uncompetitive, and orally active E. coli bacterial β-glucuronidase inhibitor, exhibiting an IC50 and a Ki of 283 nM and 164 nM, respectively.
    β-Glucuronidase-IN-1
  • HY-106282
    BIT-225 917909-71-8 98.87%
    BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM).
    BIT-225
  • HY-107126
    Ibrexafungerp 1207753-03-4 99.83%
    Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections.
    Ibrexafungerp
  • HY-107789
    Sodium lauryl sulfoacetate 1847-58-1 ≥98.0%
    Sodium lauryl sulfoacetate is a solid anionic surfactant of plant origin. Sodium lauryl sulfoacetate is an immunoadjuvant with antiimmunosuppressive effects. Sodium lauryl sulfoacetate has antiviral activity.
    Sodium lauryl sulfoacetate
  • HY-110354
    UCM05 1094451-90-7 99.58%
    UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli.
    UCM05
  • HY-110398
    5,6,7-Trimethoxyflavone 973-67-1 98.76%
    5,6,7-Trimethoxyflavone is a flavonoid compound that can be isolated from plants Callicarpa japonica. 5,6,7-Trimethoxyflavone exhibits antiviral and anti-inflammatory activities through inhibition of NF-κB/AP-1/STAT signaling pathway.
    5,6,7-Trimethoxyflavone
  • HY-111802
    3,4'-Dihydroxyflavone 14919-49-4 99.55%
    3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus.
    3,4'-Dihydroxyflavone
  • HY-113133
    Kojibiose 2140-29-6 99.76%
    Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo.
    Kojibiose
  • HY-116174
    Omaciclovir 124265-89-0 99.47%
    Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.
    Omaciclovir
  • HY-116448
    Metaflumizone 139968-49-3
    Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
    Metaflumizone
  • HY-116934
    5-Pentadecylresorcinol 3158-56-3 ≥99.0%
    5-Pentadecylresorcinol (Adipostatin A) is a glycerol-3-phosphate dehydrogenase (GPDH) inhibitor with an IC50 of 4.1 μM. Adipostatin A shows good larvicidal activity against Aedes aegypti.
    5-Pentadecylresorcinol
  • HY-118494
    Ascaridole 512-85-6 98.65%
    Ascaridole is an anthelmintic and also has antimalarial activity.
    Ascaridole
  • HY-119172
    NSC-60339 70-09-7
    NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.
    NSC-60339
  • HY-120536
    HPi1 13080-21-2 ≥98.0%
    HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum.
    HPi1
  • HY-120632
    BMS-433771 543700-68-1 99.96%
    BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease.
    BMS-433771
  • HY-121310
    Phthalocyanine 574-93-6 ≥98.0%
    Phthalocyanine is a photosensitizer. Phthalocyanine has a light-killing effect on bacterial biofilms, effectively inactivating bacteria. Phthalocyanine can be linked to anticancer drugs to target cancer. Phthalocyanine can also be used to develop chemical sensors for studying microbial infections and tumors.
    Phthalocyanine
  • HY-124614
    GLP-26 2133017-36-2 98.36%
    GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    GLP-26
Cat. No. Product Name / Synonyms Application Reactivity