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  4. Taccaceae

Taccaceae

 

Taccaceae (10):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N2416
    Taccalonolide A 108885-68-3 98.88%
    Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri, with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells.
    Taccalonolide A
  • HY-N3028
    Taccalonolide B 108885-69-4 99.46%
    Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.
    Taccalonolide B
  • HY-N11067
    Taccalonolide E 134954-57-7
    Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis.
    Taccalonolide E
  • HY-N7669
    Taccalonolide C 117803-96-0 99.13%
    Taccalonolides C is an anti-cancer agent.
    Taccalonolide C
  • HY-N0894A
    (3R,5R)-Octahydrocurcumin 408324-14-1
    (3R,5R)-Octahydrocurcumin (Compound 7) is gut microbial metabolite of Curcumin (HY-N0005). (3R,5R)-Octahydrocurcumin exhibits neuroprotective efficacy against Aβ25-35-induced cell damage in SH-SY5Y, and anti-inflammatory activity against LPS-stimulated mouse microglial BV-2.
    (3R,5R)-Octahydrocurcumin
  • HY-N15613
    α-Synuclein inhibitor 14 408324-13-0
    α-Synuclein inhibitor 14 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia officinarum. α-Synuclein inhibitor 14 can inhibit the aggregation of α-synuclein, with an inhibition rate of 72.4% at a concentration of 10 μM. α-Synuclein inhibitor 14 can be used in the research of neurodegenerative diseases such as Parkinson's disease.
    α-Synuclein inhibitor 14
  • HY-N16626
    Chantriolide B 558470-60-3
    Chantriolide B is a new withanolide glucoside. Chantriolide B can be isolated from the rhizomes of Tacca chantrieri. Chantriolide B does not inhibit NO in cells.
    Chantriolide B
  • HY-N16631
    Chantriolide A 558470-59-0
    Chantriolide A is a withanolide glucoside that can be isolated from the whole plant of Tacca plantaginea.
    Chantriolide A
  • HY-N16637
    (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside 408324-05-0
    (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside is a diarylheptanol glycoside compound isolated from Tacca plantaginea. (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside significantly inhibit TNF-α-induced NF-κB transcriptional activity (IC50 = 9.4 μM). (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside significantly activates PPAR transcriptional activity (EC50 = 9.9 μM) and has a specific activating effect on PPAR β(δ) (EC50 = 23.1 μM). (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside is non-toxic to cells at the tested concentration. (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside can be used for research on inflammatory conditions.
    (3R,5R)-3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 3-O-β-D-glucopyranoside
  • HY-N13628
    Taccaoside E 1858199-00-4
    Taccaoside E is a natural product.
    Taccaoside E