2. Natural Products
  3. Plants
  4. Scrophulariaceae
  5. Paulownia tomentosa (Thunb.) Steud.

Paulownia tomentosa (Thunb.) Steud.

Paulownia tomentosa (Thunb.) Steud. (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-124896
    Bonannione A 97126-57-3
    Bonannione A (6-Geranylnaringenin; Mimulone), a prenylflavonoid, is an orally active and potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 14 µM. Bonannione A triggers caspase-dependent apoptosis. Bonannione A induces autophagy through p53-mediated AMPK/mTOR pathway. Bonannione A shows anti-inflammatory, antiradical and anti-cancer activity.
    Bonannione A
  • HY-N10967
    Isoatriplicolide tiglate 133559-39-4
    Isoatriplicolide tiglate is a bioactive sesquiterpene lactone. Isoatriplicolide tiglate can be isolated from Paulownia coreana. Isoatriplicolide tiglate has neuroprotective effect.
    Isoatriplicolide tiglate
  • HY-N11136
    Schizolaenone C 928760-56-9
    Schizolaenone C is a natural product that can be found in Schizolaena hystrix. Schizolaenone C exhibits anti-proliferative and anti-oxidative activities.
    Schizolaenone C
  • HY-N11137
    3′-Omethyl-5′-hydroxydiplacone 1005517-26-9
    3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria.
    3′-Omethyl-5′-hydroxydiplacone
  • HY-N16129
    Diplacone 73676-38-7
    Diplacone (DP) is a geranylated flavanone. Diplacone can be isolated from the unripe fruits of Paulownia tomentosa. Diplacone has anti-inflammatory, antiradical, cytoprotective, antibacterial and anticancer activities. Diplacone induces ferroptosis-mediated cell death by increasing mitochondrial Ca2+ Influx, ROS production and mitochondrial permeability transition. Diplacone significantly inhibits AChE and BChE activity with IC50s of 7.2  μM and 1.4 μM for hAChE and BChE, respectively. Diplacone can be used for chronic inflammatory diseases like inflammatory bowel diseases (IBD), cancers like lung cancer and Alzheimer’s disease research.
    Diplacone