2. Natural Products
  3. Plants
  4. Zingiberaceae
  5. Curcuma elata Roxb.

Curcuma elata Roxb.

Curcuma elata Roxb. (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1050
    Zederone 7727-79-9 99.61%
    Zederone is a sesquiterpene. Zederone inhibits ovarian cancer cell proliferation through mTOR/p70s6K signalling pathway. Zederone inhibits CYP activities with IC50s of 2.9 μM (CYP2B6), 9.2 μM (CYP2C9), 11,2 μM (CYP2C19) and >30 μM (CYP1A2 and CYP2D6). Zederone is hepatotoxic with LD50 value at 24 hours in mice of approximately 223 mg/kg and cytotoxic against the KG1a cell line. Zederone shows antibacterial activity against a number of multi-drug resistant and Methicillin (HY-121544)-resistant Staphylococcus aureus strain. Zederone shows cognition improving capacity and assists in the modulation of gut bacterial dysbiosis.
    Zederone