1. Anti-infection
  2. Bacterial Fungal
  3. 5-Bromo-5-nitro-1,3-dioxane

5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol.

For research use only. We do not sell to patients.

5-Bromo-5-nitro-1,3-dioxane Chemical Structure

5-Bromo-5-nitro-1,3-dioxane Chemical Structure

CAS No. : 30007-47-7

Size Price Stock Quantity
50 mg USD 25 In-stock
100 mg USD 38 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

5-Bromo-5-nitro-1,3-dioxane, an antimicrobial compound, is effective against Gram-positive and Gram-negative bacteria and fungi, including yeast. 5-Bromo-5-nitro-1,3-dioxane inhibits enzyme activity and subsequent inhibition of microbial growth by the oxidation of essential protein thiol[1].

Molecular Weight

212.00

Formula

C4H6BrNO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=[N+](C1(Br)COCOC1)[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (471.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2 mg/mL (9.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7170 mL 23.5849 mL 47.1698 mL
5 mM 0.9434 mL 4.7170 mL 9.4340 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 4.7170 mL 23.5849 mL 47.1698 mL 117.9245 mL
5 mM 0.9434 mL 4.7170 mL 9.4340 mL 23.5849 mL
DMSO 10 mM 0.4717 mL 2.3585 mL 4.7170 mL 11.7925 mL
15 mM 0.3145 mL 1.5723 mL 3.1447 mL 7.8616 mL
20 mM 0.2358 mL 1.1792 mL 2.3585 mL 5.8962 mL
25 mM 0.1887 mL 0.9434 mL 1.8868 mL 4.7170 mL
30 mM 0.1572 mL 0.7862 mL 1.5723 mL 3.9308 mL
40 mM 0.1179 mL 0.5896 mL 1.1792 mL 2.9481 mL
50 mM 0.0943 mL 0.4717 mL 0.9434 mL 2.3585 mL
60 mM 0.0786 mL 0.3931 mL 0.7862 mL 1.9654 mL
80 mM 0.0590 mL 0.2948 mL 0.5896 mL 1.4741 mL
100 mM 0.0472 mL 0.2358 mL 0.4717 mL 1.1792 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5-Bromo-5-nitro-1,3-dioxane Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5-Bromo-5-nitro-1,3-dioxane
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