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  4. 4-Formylcolchicine

4-Formylcolchicine is a potent anticancer agent. 4-Formylcolchicine shows cytotoxicity activity with IC50 values of 1.007, 0.128, 0.054 μM for A549, HT-29, HCT116 cells, respectively.

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4-Formylcolchicine

4-Formylcolchicine Chemical Structure

CAS No. : 2730-82-7

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Solution
10 mM * 1 mL in DMSO Ask For Quote & Lead Time
Solid
5 mg Ask For Quote & Lead Time
10 mg Ask For Quote & Lead Time
25 mg Ask For Quote & Lead Time
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4-Formylcolchicine Related Antibodies

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Description

4-Formylcolchicine is a potent anticancer agent. 4-Formylcolchicine shows cytotoxicity activity with IC50 values of 1.007, 0.128, 0.054 μM for A549, HT-29, HCT116 cells, respectively[1][2].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
1.007 μM
Compound: 7
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
[PMID: 24900316]
HCT-116 IC50
0.054 μM
Compound: 7
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
[PMID: 24900316]
HT-29 IC50
0.128 μM
Compound: 7
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
[PMID: 24900316]
In Vitro

4-Formylcolchicine (compound 7) (0-5 μM; 24 h) shows antiproliferative activity with IC50s of 1.007, 0.128, 0.054 μM for A549, HT-29, HCT116 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Formylcolchicine Related Antibodies

Cell Viability Assay[1]

Cell Line: A549, HT-29, HCT116 cells
Concentration: 0-5 µM
Incubation Time: 24 h
Result: Inhibited cell growth with IC50s of 1.007, 0.128, 0.054 µM for A549, HT-29, HCT116 cells, respectively.
Molecular Weight

427.45

Formula

C23H25NO7
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

COC1=C2C(C([C@H](CCC2=C(C(OC)=C1OC)C=O)NC(C)=O)=C3)=CC=C(OC)C3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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4-Formylcolchicine Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Formylcolchicine2730-82-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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