3-Hydroxylidocaine

Cat. No.: HY-114914 Purity: 98.04%: Data Sheet
COA

SDS
Handling Instructions
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3-Hydroxylidocaine is the major metabolite of Lidocaine (HY-B0185) in rats and sheep.

For research use only. We do not sell to patients.

3-Hydroxylidocaine Chemical Structure

CAS No. : 34604-55-2

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	Get quote	Estimated Time of Arrival: December 31
50 mg	Get quote	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Biological Activity
Purity & Documentation
References
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Description

3-Hydroxylidocaine is the major metabolite of Lidocaine (HY-B0185) in rats and sheep^[1].

Molecular Weight

250.34

Formula

C₁₄H₂₂N₂O₂

CAS No.

34604-55-2

Appearance

Solid

Color

White to light yellow

SMILES

CC1=C(C(C)=C(C=C1)O)NC(CN(CC)CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 83.33 mg/mL (332.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9946 mL	19.9728 mL	39.9457 mL
5 mM	0.7989 mL	3.9946 mL	7.9891 mL
10 mM	0.3995 mL	1.9973 mL	3.9946 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.04%

Select Batch:

Data Sheet (266 KB) SDS (392 KB)

COA (245 KB) HNMR (245 KB) RP-HPLC (246 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Hori S, et al. Discovery of a Novel Lidocaine Metabolite by Human Liver Microsome and Identification of Microbial Species Which Produces the Same Metabolite. Chem Pharm Bull (Tokyo). 2024;72(4):393-398. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9946 mL	19.9728 mL	39.9457 mL	99.8642 mL
	5 mM	0.7989 mL	3.9946 mL	7.9891 mL	19.9728 mL
	10 mM	0.3995 mL	1.9973 mL	3.9946 mL	9.9864 mL
	15 mM	0.2663 mL	1.3315 mL	2.6630 mL	6.6576 mL
	20 mM	0.1997 mL	0.9986 mL	1.9973 mL	4.9932 mL
	25 mM	0.1598 mL	0.7989 mL	1.5978 mL	3.9946 mL
	30 mM	0.1332 mL	0.6658 mL	1.3315 mL	3.3288 mL
	40 mM	0.0999 mL	0.4993 mL	0.9986 mL	2.4966 mL
	50 mM	0.0799 mL	0.3995 mL	0.7989 mL	1.9973 mL
	60 mM	0.0666 mL	0.3329 mL	0.6658 mL	1.6644 mL
	80 mM	0.0499 mL	0.2497 mL	0.4993 mL	1.2483 mL
	100 mM	0.0399 mL	0.1997 mL	0.3995 mL	0.9986 mL