α-Dihydroartemisinin (Synonyms: α-Dihydroqinghaosu; α-Artenimol)

Cat. No.: HY-N0176A: Data Sheet Handling Instructions
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α-Dihydroartemisinin (α-Dihydroqinghaosu; α-Artenimol) is a antimalarial agent that can be found in Artemisia annua L.

For research use only. We do not sell to patients.

α-Dihydroartemisinin Chemical Structure

CAS No. : 81496-81-3

Size	Stock	Quantity
5 mg	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of α-Dihydroartemisinin:

Dihydroartemisinin In-stock

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Biological Activity
Purity & Documentation
References
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Description

α-Dihydroartemisinin (α-Dihydroqinghaosu; α-Artenimol) is a antimalarial agent that can be found in Artemisia annua L^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	2.85 μM Compound: 8; DHA	Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTS assay Antiproliferative activity against human HCT116 cells assessed as inhibition of cell viability after 48 hrs by MTS assay	[PMID: 31494469]
L02	IC₅₀	0.22 μM Compound: 1c; DHA	Cytotoxicity against human L02 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human L02 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 33636536]
SMMC-7721	IC₅₀	0.7 μM Compound: 1c; DHA	Cytotoxicity against human SMMC-7721 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human SMMC-7721 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 33636536]
WM 266-4	IC₅₀	> 40 μM Compound: 8; DHA	Antiproliferative activity against human WM266.4 cells assessed as inhibition of cell viability after 48 hrs by MTS assay Antiproliferative activity against human WM266.4 cells assessed as inhibition of cell viability after 48 hrs by MTS assay	[PMID: 31494469]

Molecular Weight

284.35

Formula

C₁₅H₂₄O₅

CAS No.

81496-81-3

SMILES

O[C@H]1[C@H](C)[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kardono, L. B. S., et al. Synthesis of dihydroartemisinin using Ni/TiO2 catalyst prepared by sol gel method. Journal of Applied Pharmaceutical Science, 2014, 4(1), Article 40101.

α-Dihydroartemisinin Related Classifications

Infection

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-Dihydroartemisinin81496-81-3α-Dihydroqinghaosu α-ArtenimolDrug MetaboliteParasiteInhibitorinhibitorinhibit

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