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Results for "

urinary diseases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adrenergic Receptor (1) Antibiotic (2) Apoptosis (1) Bacterial (4) Beta-lactamase (1) Beta-secretase (2) Cholinesterase (ChE) (2) COX (1) Dopamine Receptor (1) Drug Intermediate (1) Endogenous Metabolite (5) Endothelin Receptor (2) Epoxide Hydrolase (2) ERK (1) HDAC (1) Isotope-Labeled Compounds (1) mAChR (1) MEK (1) Monoamine Transporter (1) NADPH Oxidase (1) NF-κB (1) Prostaglandin Receptor (1) Raf (1) Ras (1) ROS Kinase (1) TGF-β Receptor (1) TRP Channel (3) α-synuclein (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (5) Endocrinology (2) Infection (3) Inflammation/Immunology (2) Metabolic Disease (8) Neurological Disease (8)

By Targets:

5-HT Receptor (1)

Adrenergic Receptor (1)

Antibiotic (2)

Apoptosis (1)

Bacterial (4)

Beta-lactamase (1)

Beta-secretase (2)

Cholinesterase (ChE) (2)

COX (1)

Dopamine Receptor (1)

Drug Intermediate (1)

Endogenous Metabolite (5)

Endothelin Receptor (2)

Epoxide Hydrolase (2)

ERK (1)

HDAC (1)

Isotope-Labeled Compounds (1)

mAChR (1)

MEK (1)

Monoamine Transporter (1)

NADPH Oxidase (1)

NF-κB (1)

Prostaglandin Receptor (1)

Raf (1)

Ras (1)

ROS Kinase (1)

TGF-β Receptor (1)

TRP Channel (3)

α-synuclein (1)

By Research Areas:

Cancer (1)

Cardiovascular Disease (5)

Endocrinology (2)

Infection (3)

Inflammation/Immunology (2)

Metabolic Disease (8)

Neurological Disease (8)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0208

Rosoxacin 1 Publications Verification Acrosoxacin	Bacterial Antibiotic	Infection
Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 µg/mL).Rosoxacin can be used in studies of urinary tract infections and certain sexually transmitted diseases .

HY-132987

Avibactam tomilopil 2 Publications Verification ARX-1796; AV-006	Beta-lactamase Bacterial Drug Intermediate	Infection
Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections .

HY-113377A

L-Glyceric acid sodium	Endogenous Metabolite	Metabolic Disease
L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2 .

HY-40161R

Indole-3-carboxylic acid (Standard)	Endogenous Metabolite	Metabolic Disease
Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .

HY-N15525

Arabinothalictoside	Epoxide Hydrolase	Cardiovascular Disease Metabolic Disease
Arabinothalictoside is found in A. squamosa L. Arabinothalictoside is a sEH inhibitor (IC₅₀: 47.1 µM). Arabinothalictoside can be used in the research of cardiovascular and urinary diseases .

HY-120322

MK-0969	mAChR	Others
MK-0969 is a M3 antagonist. MK-0969 can be used for research about chronic obstructive pulmonary disease and urinary incontinence .

HY-N15524

Thalictoside	Epoxide Hydrolase	Cardiovascular Disease Metabolic Disease Endocrinology
Thalictoside is found in A. squamosa L. Thalictoside is a sEH inhibitor (IC₅₀: 20.2 µM). Thalictoside exerts anti-osteoporotic effects through an estrogen-like mechanism. Thalictoside can be used in the research of cardiovascular and urinary diseases .

HY-N7950

16-Oxoalisol A	Others	Metabolic Disease
16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases .

HY-118064

(R)-Thionisoxetine LY-368975	Dopamine Receptor	Neurological Disease
(R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED₅₀ of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence .

HY-113377

L-Glyceric acid	Endogenous Metabolite	Metabolic Disease
L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2 .

HY-40161S

Indole-3-carboxylic acid-d4	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Indole-3-carboxylic acid-d₄ is deuterium labeled Indole-3-carboxylic acid. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases .

HY-118064A

(R)-Thionisoxetine hydrochloride LY-368975 hydrochloride	Monoamine Transporter	Neurological Disease
(R)-Thionisoxetine hydrochloride (LY-368975 hydrochloride) is a potent and selective central and peripheral norepinephrine (NE) uptake inhibitor. (R)-Thionisoxetine hydrochloride prevents 6-hydroxydopamine-induced hypothalamic NE depletion with an ED₅₀ of 0.21 mg/kg. (R)-Thionisoxetine hydrochloride can be used in the study of a variety of diseases, including depression and urinary incontinence .

HY-P1016

BQ-3020	Endothelin Receptor	Cardiovascular Disease
BQ-3020 is a selective endothelin receptor (ET_B receptor) agonist that displaces [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research ¹ ².

HY-Y1117

Melamine 1 Publications Verification	Apoptosis TGF-β Receptor NF-κB COX NADPH Oxidase ROS Kinase	Neurological Disease Inflammation/Immunology
Melamine is an orally active inducer of Apoptosis. Melamine induces animal disease models. Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function. Melamine also has neurotoxicity and nephrotoxicity. Melamine induces cognitive impairment and acute kidney injury models. Melamine can also be used to induce bladder cancer and urinary stone models .

HY-P1016B

BQ-3020 ammonium	Endothelin Receptor	Cardiovascular Disease
BQ-3020 ammonium is a selective endothelin receptor (ET_B receptor) agonist. BQ-3020 ammonium inhibits [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 ammonium elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 ammonium makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research . .

HY-40161

Indole-3-carboxylic acid	Endogenous Metabolite Bacterial	Metabolic Disease Cancer
Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against *Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease* research .

HY-15574

Piboserod 3 Publications Verification SB-207266	5-HT Receptor	Cardiovascular Disease
Piboserod is an orally available selective antagonist of the 5-HT4 receptor, with a K_i value of approximately 0.1 nM for human 5-HT4 receptors. Piboserod can competitively bind to the 5-HT4 receptor and block the activation of the 5-HT4 receptor. Piboserod can inhibit the enhancing effect of 5-HT on the nerve-mediated contraction response of the human bladder detrusor muscle. Piboserod is mainly used in the research of urinary system diseases (such as overactive bladder) and cardiovascular diseases (such as chronic heart failure) .

HY-N0702

Tenuifolin	Beta-secretase Cholinesterase (ChE)	Neurological Disease
Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD).

HY-N0702R

Tenuifolin (Standard)	Beta-secretase Cholinesterase (ChE)	Neurological Disease
Tenuifolin (Standard) is the analytical standard of Tenuifolin. This product is intended for research and analytical applications. Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD) .

HY-129397

2,3-Dinor-11beta-prostaglandin F2alpha BPG; 2,3-Dinor-11β-PGF2α; 2,3-dinor-11-epi PGF2α	Prostaglandin Receptor	Endocrinology
2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.

HY-N6670

Cefotetan	Antibiotic Raf ERK Ras MEK Bacterial	Infection
Cefotetan is a binding agent that targets human Raf1 kinase inhibitor protein (hRKIP). Cefotetan binds to hRKIP, reduces the binding space between hRKIP and Raf1 kinase, relieves hRKIP's inhibition of the Ras/Raf1/MEK/ERK signaling pathway, and enhances ERK phosphorylation. Cefotetan can be used to study diseases associated with dysregulated Ras/Raf1/MEK/ERK signaling pathways. Cefotetan is also a broad-spectrum antibacterial agent that disrupts cell wall synthesis by binding to bacterial penicillin-binding proteins (PBPs). It is used to study bacterial infections such as bone, skin, urinary tract, and lower respiratory tract .

HY-135115

Oleuropein Aglycone 3,4-DHPEA-EA	α-synuclein HDAC Adrenergic Receptor	Inflammation/Immunology
Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 (HDAC2) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy.

HY-B0985

Phenazopyridine hydrochloride 2 Publications Verification	TRP Channel	Neurological Disease
Phenazopyridine hydrochlorideis a competitive SARM1 inhibitor, with IC₅₀ 145 μM. Phenazopyridine hydrochlorideis a TRPM8 antagonist. Phenazopyridine hydrochloride has a local anesthetic/analgesic effect. Phenazopyridine hydrochlorideis used to relieve painful symptoms of conditions such as cystitis and urethritis. Phenazopyridine hydrochloridecan promote neuronal differentiation and can also be used in the study of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases .

HY-B0985A

Phenazopyridine 2 Publications Verification	TRP Channel	Neurological Disease
Phenazopyridine is a competitive SARM1 inhibitor, with IC₅₀ 145 μM. Phenazopyridine is a TRPM8 antagonist. Phenazopyridine has a local anesthetic/analgesic effect. Phenazopyridine is used to relieve painful symptoms of conditions such as cystitis and urethritis. Phenazopyridine can promote neuronal differentiation and can also be used in the study of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases .

HY-B0985R

Phenazopyridine (hydrochloride) (Standard)	TRP Channel	Neurological Disease
Phenazopyridine (hydrochloride) (Standard) is the analytical standard of Phenazopyridine (hydrochloride). This product is intended for research and analytical applications. Phenazopyridine hydrochlorideis a competitive SARM1 inhibitor, with IC₅₀ 145 μM. Phenazopyridine hydrochlorideis a TRPM8 antagonist. Phenazopyridine hydrochloride has a local anesthetic/analgesic effect. Phenazopyridine hydrochlorideis used to relieve painful symptoms of conditions such as cystitis and urethritis. Phenazopyridine hydrochloridecan promote neuronal differentiation and can also be used in the study of traumatic brain injury, peripheral neuropathy and neurodegenerative diseases .

Cat. No.	Product Name	Target	Research Area