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Results for "

twitch responses

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125743
    S-1 Methanandamide

    (S)-Methanandamide

    		 Cannabinoid Receptor Neurological Disease
    S-1 Methanandamide ((S)-Methanandamide), an Anandamide analog, is a CB1 receptor ligand with a Ki of 173 nM. S-1 Methanandamide inhibits electrically-evoked twitch response in mouse vas deferens with an IC50 value of 230 nM .
    S-1 Methanandamide
  • HY-12242
    GBR 12935 dihydrochloride

    		Dopamine Transporter Neurological Disease
    GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice .
    GBR 12935 dihydrochloride
  • HY-162423
    CYB210010

    		5-HT Receptor Androgen Receptor Neurological Disease
    CYB210010 is an orally bioavailable, long-acting serotonin 5-HT2 receptor agonist that selectively targets 5-HT2A and 5-HT2C receptors (EC50: 4.1 n, 7.3 nM). CYB210010 can enter the central nervous system, cause a head twitch response (HTR), and is not prone to behavioral tolerance during chronic administration .
    CYB210010
  • HY-117717
    (Rac)-SC-31391

    		Prostaglandin Receptor Others
    (Rac)-SC-31391, a prostaglandin analog, is a strong activator of the bladder muscle contractility that enhanced twitch responses elicited by field stimulation in the guinea pig detrusor muscle. (Rac)-SC-31391 contracts human bladder muscle through the activation of PGF2α receptors .
    (Rac)-SC-31391
  • HY-165014
    2C-I-FLY hydrochloride

    		Drug Derivative Neurological Disease
    2C-I-FLY hydrochloride is a phenethylamine that induces the head-twitch response in mice .
    2C-I-FLY hydrochloride
  • HY-138289
    4-acetoxy MPT

    		Drug Derivative Neurological Disease
    4-acetoxy MPT is a tryptamine that induces the head-twitch response (HTR) in mice .
    4-acetoxy MPT
  • HY-118802
    4-Hydroxy DPT

    		Drug Derivative Neurological Disease
    4-Hydroxy DPT is a tryptamine that induces the head-twitch response (HTR) in mice .
    4-Hydroxy DPT
  • HY-122303
    4-hydroxy DiPT hydrochloride

    		5-HT Receptor Neurological Disease
    4-hydroxy DiPT hydrochloride is an 5-HT2A agonist that induces the head-twitch response (HTR) in mice, indicating psychoactivity .
    4-hydroxy DiPT hydrochloride
  • HY-169446
    ALEPH hydrochloride

    		5-HT Receptor Neurological Disease
    ALEPH (hydrochloride) is the h5-HT2A and h5-HT2B partial agonist with the EC50 values of 10.3 nM and 19.2 nM, respectively. ALEPH (hydrochloride) causes head twitch response in mice (ED50: 0.80 mg/kg) .
    ALEPH hydrochloride
  • HY-P3679
    Neuropeptide Y (1-24) (human)

    		Neuropeptide Y Receptor Neurological Disease
    Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo .
    Neuropeptide Y (1-24) (human)
  • HY-12242A
    GBR 12935

    		Dopamine Transporter Neurological Disease
    GBR 12935 is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 also prevents the d-Fenfluramine-induced head-twitch response in mice .
    GBR 12935
  • HY-12242B
    GBR 12935 fumarate

    		Dopamine Transporter Neurological Disease
    GBR 12935 fumarate is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 fumarate stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 fumarate also prevents the d-Fenfluramine-induced head-twitch response in mice .
    GBR 12935 fumarate
  • HY-118775
    LEK 8804

    		5-HT Receptor Others
    LEK 8804 is a compound with 5-HT1A receptor agonist and 5-HT2 receptor antagonist properties, and has the activity of modulating related receptor-mediated behavioral responses. LEK 8804 can induce spontaneous tail-flick response in rats in a dose-dependent manner, showing complete 5-HT1A agonist activity, and can inhibit 5-HTP-induced head twitch response in mice, probably through antagonism of 5-HT2 receptors rather than agonism of 5-HT1A receptors.
    LEK 8804
  • HY-12242R
    GBR 12935 dihydrochloride (Standard)

    		Dopamine Transporter Neurological Disease
    GBR 12935 (dihydrochloride) (Standard) is the analytical standard of GBR 12935 (dihydrochloride). This product is intended for research and analytical applications. GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor, with the binding constant (Kd) of 1.08 nM in COS-7 cells. GBR 12935 dihydrochloride stimulates the locomotion activity in different mice strains but fails to induce stereotypy. Thus, GBR 12935 dihydrochloride also prevents the d-Fenfluramine-induced head-twitch response in mice .
    GBR 12935 dihydrochloride (Standard)

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