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Results for "

neuroblastoma (NB)

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13811
    NSC697923
    5 Publications Verification

    E1/E2/E3 Enzyme Apoptosis Cancer
    NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity .
    NSC697923
  • HY-152032

    Histone Demethylase Cancer
    LSD1-IN-23 is a competitive/non-competitive mixed inhibitor of lysine specific demethylase 1 (LSD1). LSD1-IN-23 has LSD1 inhibitory activity with an IC50 value of 0.58 μM. LSD1-IN-23 can be used for the research of neuroblastoma (NB) .
    LSD1-IN-23
  • HY-E70647

    Anaplastic lymphoma kinase (ALK) Cancer
    Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase in the insulin receptor superfamily. ALK has multiple mutants. ALK R1275Q is commonly found in neuroblastoma (NB). ALK R1275Q Recombinant Human Active Protein Kinase is a recombinant ALK R1275Q protein that can be used to study ALK R1275Q-related functions .
    ALK R1275Q Recombinant Human Active Protein Kinase
  • HY-E70643

    Anaplastic lymphoma kinase (ALK) Cancer
    Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase in the insulin receptor superfamily. ALK has multiple mutants. ALK-F1174L is commonly found in neuroblastoma (NB). ALK-F1174L Recombinant Human Active Protein Kinase is a recombinant ALK-F1174L protein that can be used to study ALK-F1174L-related functions .
    ALK F1174L Recombinant Human Active Protein Kinase
  • HY-E70714

    Anaplastic lymphoma kinase (ALK) Cancer
    EML4-ALK is a fusion-type protein tyrosine kinase produced through gene rearrangement. EML4-ALK can be used for the study of non-small cell lung carcinoma (NSCLC) and neuroblastoma (NB). EML4-ALK has multiple mutants. EML4 ALK F1174L Recombinant Human Active Protein Kinase is a recombinant EML4 ALK F1174L protein that can be used to study EML4 ALK F1174L-related functions .
    EML4 ALK F1174L Recombinant Human Active Protein Kinase

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