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nematicide activity

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119459
    Fluopyram
    1 Publications Verification

    Succinate Dehydrogenase Fungal Parasite Constitutive Androstane Receptor Caspase NF-κB Infection Cancer
    Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .
    Fluopyram
  • HY-157459

    Fungal Infection
    SDH-IN-11 (compound A7) is a SDH inhibitor, and shows inhibitory effect on nematode feeding, reproductive ability, and egg hatching. SDH-IN-11 promotes the oxidative stress of nematodes and causes intestinal damage to nematodes. SDH-IN-11 inhibits the activity of succinate dehydrogenase (SDH) in nematodes .
    SDH-IN-11
  • HY-N15498

    Insecticide Infection
    Gibepyrone D is an α-pyrone compound found in Gibberella fujikuroi and the endophytic fungus Fusarium oxysporum 162. Gibepyrone D exhibits significant lethal activity against nematodes with an LC50 value of 134 μg/mL (72 h) against the J2 larvae of Meloidogyne incognita. Gibepyrone D is promising for research of nematicides .
    Gibepyrone D
  • HY-119459R

    Reference Standards Succinate Dehydrogenase Fungal Parasite Constitutive Androstane Receptor Caspase NF-κB Infection Cancer
    Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .
    Fluopyram (Standard)

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