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Results for "

mycolic acid

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

4

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117145
    Thiophene-2

    		Bacterial Infection
    Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity .
    Thiophene-2
  • HY-122394
    Thiolactomycin

    		Antibiotic Bacterial Infection
    Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids .
    Thiolactomycin
  • HY-N15644
    Mycolic acid IIa

    		Bacterial Infection
    Mycolic acid IIa is a structural lipid component of mycobacterial cell wall. Mycolic acid IIa can be isolated from Mycobacterium bovis BCG. Mycolic acid IIa significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research .
    Mycolic acid IIa
  • HY-N15645
    α-Mycolic acid, keto cis

    		Bacterial Infection
    α-Mycolic acid, keto cis is a structural lipid component of mycobacterial cell wall. α-Mycolic acid, keto cis can be isolated from Mycobacterium tuberculosis Canetti. α-Mycolic acid, keto cis significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research .
    α-Mycolic acid, keto cis
  • HY-N15643
    α-Mycolic acid (C80)

    α-MA (C80)

    		 Bacterial Infection
    α-Mycolic acid (C80) is a structural lipid component of mycobacterial cell wall. α-Mycolic acid (C80) can be isolated from Mycobacterium tuberculosis Canetti. α-Mycolic acid (C80) significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research .
    α-Mycolic acid (C80)
  • HY-117741
    GSK951A

    		Bacterial Others
    GSK951A is a THPP analogue. GSK951A inhibits mycolic acid biosynthesis. GSK951A combines potency in culture with in vivo activity and lack of cytotoxicity .
    GSK951A
  • HY-170575
    Pks13-IN-1

    		Bacterial Infection
    Pks13-IN-1 (Compound 44) is an orally active inhibitor for Mycobacterium tuberculosis Polyketide synthase 13 (Pks13). Pks13-IN-1 inhibits M. tuberculosis strain H37Rv with a MIC of 0.07 μM. Pks13-IN-1 exhibits antibacterial efficacy in mouse model .
    Pks13-IN-1
  • HY-143473
    FabG1-IN-1

    		Bacterial Infection
    FabG1-IN-1 (Compound 29) is a potent MabA (FabG1) inhibitor with an IC50 of 38 µM .
    FabG1-IN-1
  • HY-151806
    HadAB-IN-1

    		Bacterial Infection Inflammation/Immunology
    HadAB-IN-1 is a potent HadAB inhibitor. HadAB-IN-1 inhibits HadAB enzyme complexes activity with an IC50 value of 0.03 μM. HadAB-IN-1 also affects mycolic acid biosynthesis in Mycobacterium tuberculosis (Mtb). HadAB-IN-1 can be used for the research of tuberculosis (TB) .
    HadAB-IN-1
  • HY-126564
    Ebelactone A

    		Lipase MetAP Others Inflammation/Immunology
    Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively . Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis .
    Ebelactone A
  • HY-173375
    Mycobacterium Tuberculosis-IN-8

    		Bacterial Infection
    Mycobacterium Tuberculosis-IN-8 (Compound 6g) is a selective inhibitor of Mycobacterium tuberculosis (MTB) with an MIC value of 6.25 µg/mL against MTB H37Rv. Mycobacterium Tuberculosis-IN-8 shows potent antitubercular activities, inhibiting mycolic acid biosynthesis critical for bacterial cell wall integrity. Mycobacterium Tuberculosis-IN-8 is promising for research of antitubercular agents .
    Mycobacterium Tuberculosis-IN-8
  • HY-122643
    NITD-916

    		Bacterial Infection
    NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active mycobacterial enoyl reductase InhA inhibitor with an IC50 of 570 nM. NITD-916 forms a ternary complex with InhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 inhibition of InhA reduces the synthesis of mycolic acids and results in cell death. NITD-916 has potent anti-tuberculosis effects .
    NITD-916

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