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Results for "

monitors cathepsin B

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155667A
    Z-Nle-Lys-Arg-AMC acetate

    		Cathepsin Others
    Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
    Z-Nle-Lys-Arg-AMC acetate
  • HY-155667
    Z-Nle-Lys-Arg-AMC

    		Cathepsin Fluorescent Dye Others
    Z-Nle-Lys-Arg-AMC is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .
    Z-Nle-Lys-Arg-AMC
  • HY-P5377
    Abz-HPGGPQ-EDDnp

    cathepsin K substrate

    		 Ser/Thr Protease Others
    Abz-HPGGPQ-EDDnp (Cathepsin K substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin K is the lysosomal cysteine protease involved in bone remodeling and resorption. It has potential as a drug target in autoimmune diseases and osteoporosis.This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2, 4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.)
    Abz-HPGGPQ-EDDnp

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