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Results for "

histidyl-tRNA synthetase

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W014233
    L-Histidinol dihydrochloride

    		Endogenous Metabolite Aminoacyl-tRNA Synthetase Cancer
    L-Histidinol dihydrochloride is an orally active histidyl-tRNA synthetase inhibitor. L-Histidinol dihydrochloride interferes with the initiation stage of protein synthesis, thus affecting cell proliferation and metabolism. L-Histidinol dihydrochloride has the effect of modulating the sensitivity of tumor cells to chemotherapeutic agents. L-Histidinol dihydrochloride reduces the toxicity of certain chemotherapeutic agents to normal tissues and enhance the sensitivity of tumor cells to chemotherapeutic agents .
    L-Histidinol dihydrochloride
  • HY-E70233
    Histidyl-tRNA synthetase, human

    		Others Inflammation/Immunology
    Histidyl-tRNA synthetase, human is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Histidyl-tRNA synthetase has been found to act as a particularly important antigen in autoimmune diseases such as rheumatic arthritis or myositis .
    Histidyl-tRNA synthetase, human
  • HY-W142169
    N-Formyl-L-histidine

    Formyl-L-histidine

    		 Aminoacyl-tRNA Synthetase Others
    N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a Ki value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a Ki value of 4.26 mM .
    N-Formyl-L-histidine

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