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Results for "

exosite

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Peptides

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99298
    Lampalizumab

    RG 7417; TNX 234; Anti-CFD Recombinant Antibody

    		 Complement System Inflammation/Immunology
    Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research .
    Lampalizumab
  • HY-P2021
    BMS 180742

    		Thrombin Cardiovascular Disease
    BMS 180742 is a thrombin exosite inhibitor. BMS 180742 does not inhibit arterial thrombosis .
    BMS 180742
  • HY-P2490
    Acetyl-Hirudin (54-65) sulfated

    		Thrombin Metabolic Disease
    Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex .
    Acetyl-Hirudin (54-65) sulfated
  • HY-P991065
    Ichorcumab

    JNJ-375; JNJ-64179375; JNJ-9375

    		 Thrombin Cardiovascular Disease
    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets Thrombin. Ichorcumab binds to exosite 1 on thrombin and inhibits substrate binding but not catalytic activity. The isotype control for Ichorcumab can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
    Ichorcumab

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