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Results for "

decarboxylation

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

2

Peptides

2

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111177
    Pheneturide

    Ethylphenacemide; M 551

    		 Drug Metabolite Neurological Disease
    Pheneturide (Ethylphenacemide, M 551), a decarboxylation product of Phenobarbital, can be used to prevent psychomotor seizures .
    Pheneturide
  • HY-111177R
    Pheneturide (Standard)

    Ethylphenacemide (Standard); M 551 (Standard)

    		 Drug Metabolite Reference Standards Neurological Disease
    Pheneturide (Standard) is the analytical standard of Pheneturide. This product is intended for research and analytical applications. Pheneturide (Ethylphenacemide, M 551), a decarboxylation product of Phenobarbital, can be used to prevent psychomotor seizures .
    Pheneturide (Standard)
  • HY-P2837
    Oxaloacetate decarboxylase

    		Endogenous Metabolite Metabolic Disease
    Oxaloacetate decarboxylase catalyzes the irreversible decarboxylation of oxaloacetate to pyruvate and COIC2. Oxaloacetate decarboxylase is a member of the sodium ion transport decarboxylase (NaT-DC) enzyme family. Oxaloacetate decarboxylase converts the chemical energy of the decarboxylation reaction into an electrochemical gradient of Na + ions across the membrane .
    Oxaloacetate decarboxylase
  • HY-P2796
    Pyruvate decarboxylase

    PDC

    		 Biochemical Assay Reagents Metabolic Disease
    Pyruvate decarboxylase (PDC) is an enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde. Pyruvate decarboxylase catalyses the non-oxidative conversion of pyruvate (or other 2-oxo acids) to acetaldehyde and CO2 .
    Pyruvate decarboxylase
  • HY-W327449
    Feruloylputrescine

    		Cytochrome P450 Cardiovascular Disease Metabolic Disease
    Feruloylputrescine is an oral active phenolamide found in citrus plants and formed through the decarboxylation of L-Arginine. Feruloylputrescine inhibits monooxygenase (cntA) and reductase (cntB) and trimethylamine production. Feruloylputrescine can be used for cardiovascular diseases research .
    Feruloylputrescine
  • HY-P2891
    Pyruvate Oxidase, Microorganisms

    PoxB

    		 Pyruvate Oxidase Others
    Pyruvate Oxidase, Microorganisms (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide and water. Pyruvate oxidase is an important enzyme in bacterial metabolism and is often used in biochemical research .
    Pyruvate Oxidase, Microorganisms
  • HY-E70570
    Glutamate decarboxylase

    		GABA Receptor Metabolic Disease
    Glutamate decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide (CO2). Many gut microbes can metabolize glutamate via their Glutamate decarboxylase in a pyridoxal-5′-phosphate (PLP) dependent manner .
    Glutamate decarboxylase
  • HY-130431
    Vinclozolin M2

    		Parasite Infection
    Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.
    Vinclozolin M2
  • HY-W327449R
    Feruloylputrescine (Standard)

    		Cytochrome P450 Cardiovascular Disease Metabolic Disease
    Feruloylputrescine is an oral active phenolamide found in citrus plants and formed through the decarboxylation of L-Arginine. Feruloylputrescine inhibits monooxygenase (cntA) and reductase (cntB) and trimethylamine production. Feruloylputrescine can be used for cardiovascular diseases research .
    Feruloylputrescine (Standard)
  • HY-172532
    Acetylagmatine acetate

    N-Acetylagmatine acetate

    		 Drug Derivative Neurological Disease
    Acetylagmatine (N-Acetylagmatine) acetate is a product formed by agmatine N-acetyltransferase (AgmNAT) catalyzing the reaction of acetyl-CoA and Agmatine (HY-101238). Agmatine is the product of arginine decarboxylation. Agmatine is a neurotransmitter and neuromodulator in mammalian brain .
    Acetylagmatine acetate
  • HY-P2993
    Isocitrate dehydrogenase, Porcine heart

    ICDH; IDH

    		 Isocitrate Dehydrogenase (IDH) Metabolic Disease Cancer
    Isocitrate dehydrogenase, Porcine heart (ICDH) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) + to NAD(P)H, it plays important roles in cellular metabolism .
    Isocitrate dehydrogenase, Porcine heart
  • HY-P2993A
    Isocitrate dehydrogenase, Microorganism

    ICDH, Microorganism; IDH, Microorganism

    		 Isocitrate Dehydrogenase (IDH) Metabolic Disease
    Isocitrate dehydrogenase, Microorganism (IDH) (EC 1.1.1.42) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD(P) + to NAD(P)H, it plays important roles in cellular metabolism .
    Isocitrate dehydrogenase, Microorganism
  • HY-P2891A
    Pyruvate oxidase, Aerococcus viridans

    PoxB, Aerococcus viridans

    		 Endogenous Metabolite Others
    Pyruvate oxidase, Aerococcus viridans (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to produce acetyl phosphate, carbon dioxide, and water. Pyruvate oxidase, Aerococcus viridans is an important enzyme in bacterial metabolism and can enhance ATP production. Additionally, Pyruvate oxidase, Aerococcus viridans can be used for the determination of aspartate aminotransferase and alanine aminotransferase activities .
    Pyruvate oxidase, Aerococcus viridans
  • HY-E70518
    Oxalate decarboxylase, Microorganism

    		Bacterial Infection
    Oxalate decarboxylase, Microorganism (EC 4.1.1.2), a stress-response enzyme in certain soil bacteria, is a Mn-dependent enzyme in the cupin superfamily and is found in fungi and soil bacteria. Oxalate decarboxylase catalyzes the decarboxylation of the oxalate mono-anion in the soil bacterium Bacillus subtilis. Enzymatic activity of OxDC is strongly pH dependent, with a maximum at around pH 4.0 .
    Oxalate decarboxylase, Microorganism
  • HY-178711
    18-Oxooctadecanoic acid

    		Others Metabolic Disease
    18-Oxooctadecanoic acid is a long-chain fatty acid derivative. 18-Oxooctadecanoic acid is exclusively oxidized by P450BM-3 to the corresponding α,ω-dicarboxylic acid (1,18-octadecanedioic acid) without undergoing decarboxylation to form one-carbon-shorter olefins. 18-Oxooctadecanoic acid can be used for the study of metabolic pathways of aldehyde-containing long-chain fatty acids .
    18-Oxooctadecanoic acid
  • HY-19094
    DuP-532

    		Angiotensin Receptor Cardiovascular Disease
    DuP-532 is an angiotensin type 1 receptor antagonist with potential activity in the suppression of hypertension and heart failure. DuP-532 can react with a range of aryl and heteroaryl halides to form perfluoroalkyl(hetero)arenes in moderate to high yields. Computational studies of DuP-532 suggest that coordination of a second phenyl ring ligand may lower the energy barrier for decarboxylation of perfluorocarboxylates, thereby promoting the perfluoroalkylation reaction .
    DuP-532
  • HY-114118S1
    Semaglutide-d8 tetraTFA

    		Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family Neurological Disease Metabolic Disease Cancer
    Semaglutide-d8 tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
    Semaglutide-d8 tetraTFA
  • HY-114118S
    Semaglutide-d8

    		Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family Neurological Disease Metabolic Disease Cancer
    Semaglutide-d8 is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
    Semaglutide-d8
  • HY-112747
    Soy PE

    LPI; PE (soy)

    		 Phospholipase Infection
    Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions.
    Soy PE

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