Search Result
Results for "
dTTP sodium
" in MedChemExpress (MCE) Product Catalog:
9
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-158715
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3'-ONH2-dTTP sodium solution (100mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-138615S5
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- HY-138615S1
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- HY-138615S2
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- HY-W013715A
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- HY-138615A
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- HY-138615
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- HY-158676
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- HY-158716
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3'-O-Methylthiomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158672
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-138615S3
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- HY-138615S4
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- HY-W013715B
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dTTP trisodium,100 mM Solution,PCR Grade
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Biochemical Assay Reagents
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Others
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Deoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade (dTTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication and can be used for PCR analysis. This product is provided in the form of aqueous solution .
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- HY-D1029
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- HY-D1029A
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- HY-158707
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- HY-170224
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Biochemical Assay Reagents
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Others
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dNTP Mixture, 10 mM Solution, PCR Grade is an equimolar mixture of dATP, dGTP, dCTP, and dTTP, suitable for amplification reactions of biology applications including PCR .
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- HY-170238
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Biochemical Assay Reagents
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Others
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dNTP Mixture,25 mM Solution,PCR Grade is an equimolar mixture of dATP, dGTP, dCTP, and dTTP, suitable for amplification reactions of biology applications including PCR .
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- HY-D1811
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VF 555-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 555-dUTP (VF 555-dUTP) can be used to produce biotinylated DNA probes in a variety of assay applications by enzymatic incorporation into DNA/cDNA, replacing its natural counterpart, dTTP .
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- HY-D1810
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Fluorescent Dye
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Others
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Sulfo-Cy3-E-dUTP is enzymatically incorporated into DNA/cDNA as a substitute for its natural counterpart, dTTP. Sulfo-Cy3-E-dUTP can be used to produce biotinylated DNA probes for various detection applications .
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- HY-D1812
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VF 488-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 488-dUTP (VF 488-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1814
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VF 640-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1813
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VF 594-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 594-dUTP (VF 594-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-W017068A
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2'-Deoxyuridine-5'-triphosphate sodium salt
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Biochemical Assay Reagents
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Others
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dUTP sodium is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .
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- HY-15353
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MKC-442
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HIV
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Infection
Inflammation/Immunology
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Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity .
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- HY-D1022A
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Biotin-16-deoxyuridine-5'-triphosphate trisodium
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DNA Stain
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Others
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Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1022
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Biotin-16-deoxyuridine-5'-triphosphate
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Fluorescent Dye
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Others
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Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-90006
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5-Fluorouracil
Maximum Cited Publications
246 Publications Verification
5-FU
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-W017068
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2'-Deoxyuridine-5'-triphosphate trisodium salt
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DNA/RNA Synthesis
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Others
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dUTP trisodium (2´-Deoxyuridine, 5´-Triphosphate) is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .
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- HY-131576
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dTDP
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Endogenous Metabolite
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Infection
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Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .
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- HY-131576A
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dTDP sodium
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Endogenous Metabolite
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Infection
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Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .
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- HY-90006S
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- HY-90006R
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5-FU (Standard)
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Reference Standards
Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S2
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S3
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5-FU-13C4,15N2
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Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S1
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5-FU-13C,15N2
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Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-W719041
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HIV
Reverse Transcriptase
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Infection
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1,6-Di-O-galloyl-β-D-glucose is a compound found in the fruit of Phyllanthus emblica. 1,6-Di-O-galloyl-β-D-glucose has HIV-1 reverse transcriptase (RT) inhibitory activity with an IC50 value of 270 μM. The inhibitory mechanism of 1,6-Di-O-galloyl-β-D-glucose is competitive inhibition of the template primer and non-competitive inhibition of the substrate (dTTP). 1,6-Di-O-galloyl-β-D-glucose can be used in anti-HIV research .
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- HY-116973
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HIV
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Infection
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L-738372 is a non-competitive reversible inhibitor of HIV-1 reverse transcriptase (RT) with an inhibition constant (Ki) of 140 nM against dTTP. When combined with any nucleoside analogs (such as azidothymidine triphosphate, didexoyinosine triphosphate, or didexoycytidine triphosphate), L-738372 exhibits synergistic inhibition of RT activity. L-738372 has 2-3 times more inhibitory potency against the azidothymidine-resistant RT (D67N, K70R, T215Y, K219Q) compared to the wild-type RT. L-738372 holds promise for research in the field of HIV virus treatment .
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- HY-16638
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PDDF
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Thymidylate Synthase
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Metabolic Disease
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CB 3717 is a potent inhibitor of human thymidylate synthetase, competitively binding with 5,10-methylenetetrahydrofolate (Ki = 4.9 X 10(-9) M). It also competitively inhibits human dihydrofolate reductase with dihydrofolate (Ki = 2.3 X 10(-8) M). In WI-L2 human lymphoblastoid cells, CB 3717 treatment led to a significant decrease in cellular dTTP levels and a notable increase in dUMP levels, indicating a disruption in nucleotide metabolism. The growth-inhibitory effect of CB 3717 was reversed by thymidine supplementation, demonstrating that thymidylate synthetase became rate-limiting in the presence of this compound. Delayed thymidine supplementation beyond 8 hours resulted in severe cytotoxicity, underscoring the critical timing of nucleotide rescue strategies in CB 3717-treated cells .
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Cat. No. |
Product Name |
Type |
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- HY-D1029A
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- HY-D1811
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VF 555-dUTP
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Dyes
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Vari Fluor 555-dUTP (VF 555-dUTP) can be used to produce biotinylated DNA probes in a variety of assay applications by enzymatic incorporation into DNA/cDNA, replacing its natural counterpart, dTTP .
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- HY-D1812
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VF 488-dUTP
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Dyes
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Vari Fluor 488-dUTP (VF 488-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1814
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VF 640-dUTP
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Dyes
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Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1813
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VF 594-dUTP
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Dyes
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Vari Fluor 594-dUTP (VF 594-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1022A
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Biotin-16-deoxyuridine-5'-triphosphate trisodium
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Fluorescent Dyes/Probes
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Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1029
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- HY-D1810
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Dyes
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Sulfo-Cy3-E-dUTP is enzymatically incorporated into DNA/cDNA as a substitute for its natural counterpart, dTTP. Sulfo-Cy3-E-dUTP can be used to produce biotinylated DNA probes for various detection applications .
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- HY-D1022
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Biotin-16-deoxyuridine-5'-triphosphate
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Fluorescent Dyes/Probes
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Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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Cat. No. |
Product Name |
Type |
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- HY-158715
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Gene Sequencing and Synthesis
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3'-ONH2-dTTP sodium solution (100mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-W013715A
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dTTP (trisodium) solution (100mM)
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Gene Sequencing and Synthesis
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Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA .
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- HY-158676
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Gene Sequencing and Synthesis
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3'-P-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158716
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Gene Sequencing and Synthesis
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3'-O-Methylthiomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158672
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Gene Sequencing and Synthesis
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-W013715B
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dTTP trisodium,100 mM Solution,PCR Grade
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Cell Assay Reagents
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Deoxythymidine-5'-triphosphate trisodium,100 mM Solution,PCR Grade (dTTP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA chains during DNA replication and can be used for PCR analysis. This product is provided in the form of aqueous solution .
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- HY-158707
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Gene Sequencing and Synthesis
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dTTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-170224
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Cell Assay Reagents
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dNTP Mixture, 10 mM Solution, PCR Grade is an equimolar mixture of dATP, dGTP, dCTP, and dTTP, suitable for amplification reactions of biology applications including PCR .
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- HY-170238
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Cell Assay Reagents
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dNTP Mixture,25 mM Solution,PCR Grade is an equimolar mixture of dATP, dGTP, dCTP, and dTTP, suitable for amplification reactions of biology applications including PCR .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-138615S5
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Deoxythymidine-5'-triphosphate-d15 (dTTP-d15) dilithium is the deuterium labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA .
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- HY-138615S1
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Deoxythymidine-5'-triphosphate- 15N2 (dTTP- 15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S2
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Deoxythymidine-5'-triphosphate- 13C10 (dTTP- 13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-90006S
-
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5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S2
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5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S1
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5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-138615S3
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Deoxythymidine-5'-triphosphate- 15N2,d15 (dTTP- 15N2,d15) dilithium is deuterium and 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S4
-
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Deoxythymidine-5'-triphosphate- 13C10, 15N2 (dTTP- 13C10, 15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-90006S3
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5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil . 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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Cat. No. |
Product Name |
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Classification |
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- HY-158672
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Azide
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
|
Cat. No. |
Product Name |
|
Classification |
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- HY-W013715A
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dTTP (trisodium) solution (100mM)
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Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA .
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- HY-138615A
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dTTP sodium hydrate
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Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate trisodium salt is used in the synthesis of DNA .
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- HY-138615
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dTTP
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Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA .
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