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Results for "

crosslink of collagen

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113403

    Endogenous Metabolite Others
    Pyridinoline, a fluorescent material, is a bone resorption biomarker. Pyridinoline also is a type crosslink of collagen .
    Pyridinoline
  • HY-107829
    3-Aminopropionitrile fumarate (2:1)
    5 Publications Verification

    Di-β-aminopropionitrile fumarate; β-Aminopropionitrile fumarate; β-Ammoniumpropionitrile hemifumarate

    MMP Others
    3-Aminopropionitrile fumarate (2:1) is a lathyrogen which inhibits crosslinking of collagen.
    3-Aminopropionitrile fumarate (2:1)
  • HY-29035

    Collagen Others
    Dopamine acrylamide, a polyphenol derivative, can cross-link collagen mainly via noncovalent bonding under acidic-non-oxidized conditions .
    Dopamine acrylamide
  • HY-151498A

    Monoamine Oxidase Others
    PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts .
    PXS-4787 hydrochloride
  • HY-Y0623
    N-Hydroxysuccinimide
    1 Publications Verification

    HOSu; 1-Hydroxy-2,5-pyrrolidinedione

    Biochemical Assay Reagents Others
    N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .
    N-Hydroxysuccinimide
  • HY-W740191

    DHLNL

    Biochemical Assay Reagents Others
    Dihydroxylysinonorleucine is a reducible lysine-derived cross-link. Dihydroxylysinonorleucine can be used for the cross-linking of Collagen .
    Dihydroxylysinonorleucine
  • HY-W738852

    Isotope-Labeled Compounds Endogenous Metabolite Others
    Hydroxylysylpyridinoline-d6 is deuterium labeled Pyridinoline. Pyridinoline, a fluorescent material, is a bone resorption biomarker. Pyridinoline also is a type crosslink of collagen .
    Hydroxylysylpyridinoline-d6
  • HY-113115A

    Amino Acid Derivatives Cancer
    L-Allysine is an oxidized derivative of lysine, produced by lysine oxidase (LOX). L-Allysine plays a key role in the cross-linking of collagen in fibrotic reactions. L-Allysine can be used in the study of pancreatic cancer.
    L-Allysine
  • HY-171955

    Lipoxygenase Apoptosis Reactive Oxygen Species (ROS) FAK Cancer
    LXG6403 is an orally active and irreversible LOX inhibitor (IC50 = 1.3 μM). LXG6403 is ~3.5-fold more specific for LOX than LOXL2 and does not inhibit LOXL1. LXG6403 inhibits FAK signaling and induces ROS generation and DNA damage, leading to G1 arrest and apoptosis in chemoresistant triple-negative breast cancer (TNBC) cell lines. LXG6403 alters the extracellular matrix (ECM) and collagen structure, reducing collagen cross-linking and deposition, thereby increasing drug penetration and reducing tumor stiffness. LXG6403 overcomes Doxorubicin resistance in chemoresistant TNBC PDX in vivo and can be used to study high-stiffness resistant tumors .
    LXG6403

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