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Results for "

bisindole alkaloid

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

5

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0117
    Indirubin
    5+ Cited Publications

    Couroupitine B; Indigo red; Indigopurpurin

    		 Apoptosis Cancer
    Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    Indirubin
  • HY-N0117A
    (Z)-Indirubin

    (Z)-Couroupitine B; (Z)-Indigo red; (Z)-Indigopurpurin

    		 Apoptosis Cancer
    (Z)-Indirubin is an isomer of Indirubin (HY-N0117). Indirubin is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    (Z)-Indirubin
  • HY-169339
    Villalstonine

    		Parasite Infection Cancer
    Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC50 value of 0.27 μM .
    Villalstonine
  • HY-117164
    Longicautadine

    		Others Others
    Longicautadine is a bisindole alkaloid that can be isolated from the root and stem bark of Strychnos nux vomica.
    Longicautadine
  • HY-176305S
    Neurofilament, U-15N

    		Isotope-Labeled Compounds Neurological Disease
    Neurofilament, U- 15N is the 15N-labeled Neurofilament.
    Neurofilament, U-15N
  • HY-N0117R
    Indirubin (Standard)

    Couroupitine B (Standard); Indigo red (Standard); Indigopurpurin (Standard)

    		 Reference Standards Apoptosis Cancer
    Indirubin (Standard) is the analytical standard of Indirubin. This product is intended for research and analytical applications. Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia .
    Indirubin (Standard)
  • HY-113796
    Kopsoffinol

    		Others Cancer
    Kopsoffinol, a bisindole alkaloid, shows in vitro growth inhibitory activity against human PC-3, HCT-116, MCF-7, and A549 cells and moderate effects in reversing multidrug-resistance in vincristine-resistant human KB cells .
    Kopsoffinol
  • HY-121178
    Deoxyviolacein

    		Bacterial Fungal Infection
    Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
    Deoxyviolacein
  • HY-175180
    Conophyllidine

    		Histone Acetyltransferase Arginase Inflammation/Immunology Cancer
    Conophyllidine, a bisindole alkaloid, is a selective M2 polarization inhibitor. Conophyllidine inhibits histone acetylation by targeting the histone acetyltransferase domain of the P300/CBP proteins. Conophyllidine inhibits IL-4-induced arginase with an IC50 of 0.31 μM. Conophyllidine effectively induces a phenotypic switch in tumor-associated macrophages (TAMs) from an anti-inflammatory to an inflammatory type, thereby enhancing cytotoxic CD8+ T cell recruitment and functionality within the tumor microenvironment. Conophyllidine can be used for the study of TAMs .
    Conophyllidine

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