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Results for "

amine reactive

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Reactive Oxygen Species (ROS) (2) ADC Linker (12) Biochemical Assay Reagents (120) DNA Stain (2) Drug-Linker Conjugates for ADC (3) E3 Ligase Ligand-Linker Conjugates (2) Fluorescent Dye (46) Ligands for E3 Ligase (2) Liposome (7) Microtubule/Tubulin (1) Monoamine Oxidase (1) PROTAC Linkers (14)
By Research Areas:	Cancer (34) Infection (1) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (2)
Click Chemistry:	TCO (1) PROTAC Synthesis (2) Azide (3) Alkynes (1)
Oligonucleotides:	Pegylated Lipids (4) Phospholipids (3)

209

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Click Chemistry

Oligonucleotides

Targets Recommended: Amine N-methyltransferase Reactive Oxygen Species (ROS) Trace Amine-associated Receptor (TAAR) VAP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1662

BDP 558/568 NHS ester BODIPY 558/568SE	Fluorescent Dye	Others
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 .

HY-147117

NHS-SS-Ac	Biochemical Assay Reagents	Others
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid .

HY-D1469

5-Carboxyrhodamine 6G succinimidyl ester R6G-SE	Fluorescent Dye	Others
5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye .

HY-D1112

TFAX 546,SE triethylammonium	Fluorescent Dye	Others
TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies .

HY-156384

SCO-PEG4-NHS	Biochemical Assay Reagents	Others
SCO-PEG4-NHS is a NH₂ reactive compound .

HY-W800650

Aminooxy-PEG1-amine	Biochemical Assay Reagents	Others
Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.

HY-W800711

SPDP-Gly-Pro-NHS ester	Biochemical Assay Reagents	Others
SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.

HY-W190918

endo-BCN-PEG4-amine	Biochemical Assay Reagents	Others
endo-BCN-PEG4-amine is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-D1049

DNP-X acid 6-((2,4-Dinitrophenyl)amino)hexanoic acid	Fluorescent Dye	Metabolic Disease
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-W020546

DBCO-amine TFA	Biochemical Assay Reagents	Others
DBCO-amine TFA is a simple building block containing a DBCO moiety and an amine group. Amine is very reactive with NHS ester. DBCO is commonly used for copper-free Click Chemistry reactions.

HY-155885

mPEG-amine (MW 40000) mPEG-NH2 (MW 40000)	Biochemical Assay Reagents	Others
mPEG-amine (MW 40000) (mPEG-NH2 (MW 40000)) is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent .

HY-W012971

5-Amino-1-pentanol	Biochemical Assay Reagents	Others
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-W749072

BP Fluor 568 NHS ester	Fluorescent Dye	Others
BP Fluor 568 NHS ester is an amine-reactive, orange fluorescent dye routinely used to label proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules (Ex/Em: 578 nm/602 nm) .

HY-131097

Malachite green isothiocyanate	Fluorescent Dye	Others
Malachite green isothiocyanate is an amine-reactive probe that reacts with amines to give the corresponding thiourea. Malachite green isothiocyanate is a reagent that has been used for the measurement of concentration of protein .

HY-W093254A

Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250)	Biochemical Assay Reagents	Others
Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250) is an amine-reactive crosslinking agent .

HY-140339

ANB-NOS	Biochemical Assay Reagents	Others
ANB-NOS is a heterobifunctional crosslinker that contain an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide .

HY-W093254B

Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600)	Biochemical Assay Reagents	Others
Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600) is an amine-reactive crosslinking agent .

HY-W998707

TAMRA amine, 5-isomer hydrochloride	Fluorescent Dye	Others
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-132270

FAM amine, 5-isomer	Fluorescent Dye	Others
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.

HY-D1372

Cyanine3 amine hydrochloride	Fluorescent Dye	Others
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-W591379

Amino-PEG19-amine	Biochemical Assay Reagents	Others
Amino-PEG19-amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.

HY-D1774

5-ROX-SE	Fluorescent Dye	Others
5-ROX-SE is the amine-reactive form of 5-carboxy-X-rhodamine single isomer.

HY-D0135

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid	Fluorescent Dye	Others
12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye .

HY-W800839

TCO-PEG4-TFP ester	Biochemical Assay Reagents	Others
TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.

HY-W154175

Boc-DODA	Biochemical Assay Reagents	Others
Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-D1372A

Cyanine3 amine TFA	Fluorescent Dye	Others
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-169754

BP Fluor 350 NHS ester	Fluorescent Dye	Others
BP Fluor 350 NHS ester is an amine reactive, water soluble, blue emitting dye used to specifically and efficiently modify primary amines at pH 7-9 to form stable covalent amide bonds .

HY-D1089

6-JOE, SE	Fluorescent Dye	Others
6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .

HY-W590569

Azido-PEG12-amine	Biochemical Assay Reagents	Others
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.

HY-D1050

DNP-X, SE 1 Publications Verification 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester	Fluorescent Dye	Metabolic Disease
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-W585386

BDP TMR amine hydrochloride	Fluorescent Dye	Others
BDP TMR amine hydrochloride is a BDP dye linker is very bright which makes it useful for processes such as determining quantum yield. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-W479025

Fmoc-DODA hydrochloride	Biochemical Assay Reagents	Others
Fmoc-DODA hydrochloride is a linker with an Fmoc-protected amine and a terminal amine group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-W800654

Mal-PEG5-amine	Biochemical Assay Reagents	Others
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

HY-D1607

BODIPY FL SSE	Fluorescent Dye	Others
BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λ_ex=502 nm, λ_em=511 nm) .

HY-W190922

Mal-PEG4-amine	Biochemical Assay Reagents	Others
Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

HY-W800649

Aminooxy-PEG2-amine hydrochloride	Biochemical Assay Reagents	Others
Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .

HY-141175

TCO-PNB ester	Biochemical Assay Reagents	Others
TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group .

HY-W441013

DSPE-PEG-NHS, MW 1000	Liposome	Others
DSPE-PEG-NHS, MW 1000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 1000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 1000 can be used in the study of drug delivery .

HY-140895B

Biotin-PEG-Amine (MW 10000) Biotin-PEG-NH2 (MW 10000)	Biochemical Assay Reagents	Others
Biotin-PEG-Amine (MW 10000) (Biotin-PEG-NH2 (MW 10000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895C

Biotin-PEG-Amine (MW 20000) Biotin-PEG-NH2 (MW 20000)	Biochemical Assay Reagents	Others
Biotin-PEG-Amine (MW 20000) (Biotin-PEG-NH2 (MW 20000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895D

Biotin-PEG-Amine (MW 40000) Biotin-PEG-NH2 (MW 40000)	Biochemical Assay Reagents	Others
Biotin-PEG-Amine (MW 40000) (Biotin-PEG-NH2 (MW 40000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895A

Biotin-PEG-Amine (MW 5000) Biotin-PEG-NH2 (MW 5000)	Biochemical Assay Reagents	Others
Biotin-PEG-Amine (MW 5000) (Biotin-PEG-NH2 (MW 5000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-W190915

4,7,10,13,16-Pentaoxanonadecane-1,19-diamine	Biochemical Assay Reagents	Others
4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dye	Others
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .

HY-W092344

1,5-Bis-boc-1,5,9-triazanonane	Biochemical Assay Reagents	Others
1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-W712314

4-Arm PEG-amine (MW 5000)	Biochemical Assay Reagents	Others
4-Arm PEG-amine (MW 5000) is a PEG Linker. The reactive primary amine or NH2 rapidly react with aldehyde, ketone to form imine. Imine upon further reduction forms secondary amine via reductive amination. Amine reacts with activated carboxyl acid, NHS ester to form stable amide bonds. 4-Arm PEG reagents are useful crosslinking reagent and used for drug delivery .

HY-D2746

Cy5.5 bis-NHS ester	Fluorescent Dye	Others
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.

HY-W1048567H

mPEG-SCM (MW 3400)	Biochemical Assay Reagents	Others
mPEG-SCM (MW 3400) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567

mPEG-SCM (MW 1000)	Biochemical Assay Reagents	Others
mPEG-SCM (MW 1000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

Cat. No.	Product Name	Type

HY-D1662

BDP 558/568 NHS ester BODIPY 558/568SE	Fluorescent Dyes/Probes
BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 .

HY-D0135

12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid	Fluorescent Dyes/Probes
12-(7-Nitrobenzofurazan-4-ylamino)dodecanoic acid is an amine-reactive fluorescent dye .

HY-D1372A

Cyanine3 amine TFA	Fluorescent Dyes/Probes
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-D1469

5-Carboxyrhodamine 6G succinimidyl ester R6G-SE	Fluorescent Dyes/Probes
5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye .

HY-D1112

TFAX 546,SE triethylammonium	Fluorescent Dyes/Probes
TFAX 546,SE triethylammonium, an amine reactive yellow fluorescent dye, can forms bright and photostable conjugates with proteins and antibodies .

HY-D1049

DNP-X acid 6-((2,4-Dinitrophenyl)amino)hexanoic acid	Fluorescent Dyes/Probes
DNP-X acid (6-((2,4-Dinitrophenyl)amino)hexanoic acid), an amine-reactive building block for developing a probe, can be recognized by anti-DNP antibodies. DNP-X acid is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-W998707

TAMRA amine, 5-isomer hydrochloride	Fluorescent Dyes/Probes
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-132270

FAM amine, 5-isomer	Fluorescent Dyes/Probes
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.

HY-D1372

Cyanine3 amine hydrochloride	Fluorescent Dyes/Probes
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-D1774

5-ROX-SE	Fluorescent Dyes/Probes
5-ROX-SE is the amine-reactive form of 5-carboxy-X-rhodamine single isomer.

HY-D1089

6-JOE, SE	Fluorescent Dyes/Probes
6-JOE, SE is an amine-reactive fluorescent probe and is suitable for postsynthetic labeling of amino-modified oligonucleotides .

HY-D1050

DNP-X, SE 1 Publications Verification 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester	Fluorescent Dyes/Probes
DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester), the DNP-X acid modified by succinimidyl ester, is an amine-reactive building block for developing a probe, which can be recognized by anti-DNP antibodies. DNP-X, SE (6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester) is also an excellent amine-reactive FRET quencher paired with Trp or Tyr.

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dyes/Probes
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-D1607

BODIPY FL SSE	Protein Labeling
BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λ_ex=502 nm, λ_em=511 nm) .

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dyes/Probes
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .

HY-D2746

Cy5.5 bis-NHS ester	Fluorescent Dyes/Probes
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.

HY-D0026

AMCA,SE 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester	Fluorescent Dyes/Probes
7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a bioReagent, suitable for fluorescence, can be used for amine-reactive labeling.

HY-D0799A

Sulfo-NHS-LC-Biotin	Dyes
Sulfo-NHS-LC-Biotin is an amine-reactive ester derivative of biotin and cannot pass the intact blood-retinal barrier. It can be used to assess vascular permeability of the brain and retinal vasculature.

HY-D1041

ICG-OSu ICG NHS ester	Fluorescent Dyes/Probes
ICG-OSu (ICG NHS ester) is a near-infrared fluorescent agent ICG derivative. ICG-OSu is amine-reactive and has been widely used to design in vivo imaging probes .

HY-D0048

5-TAMRA-SE 2 Publications Verification 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester	Fluorescent Dyes/Probes
5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability (Ex/Em = 565/580 nm).

HY-111496

Sulfo-NHS-SS-Biotin sodium 2 Publications Verification	Dyes
Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .

HY-D0029

5(6)-Aminofluorescein 1 Publications Verification 5(6)-AFM; Fluoresceinamine mixed isomers	Fluorescent Dyes/Probes
5(6)-Aminofluorescein (5(6)-AFM) is a a precursor for synthesis of 5(6)-FITC (HY-15941). 5(6)-FITC is an amine-reactive derivative of fluorescein dye.

HY-D2367

Rhodamine B NHS ester	Dyes
Rhodamine B NHS ester is a fluorophore featuring an NHS ester. Rhodamine B is a fluorescent dye which is used in fluorescence-based assays in vivo. NHS esters are highly reactive towards amines, forming amides under mild conditions.

HY-D2736

BP Light 800 NHS ester	Fluorescent Dyes/Probes
BP Light 800 NHS ester is an amine reactive hydrophilic fluorochrome . It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.

HY-D0049

6-TAMRA-SE 1 Publications Verification 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester	Oligonucleotide Labeling
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .

HY-D1085

AMCA-X SE	Fluorescent Dyes/Probes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-D1389

Sulfo-CY-5.5 NHS ester tripotassium Sulfo-Cyanine5.5 NHS ester tripotassium	Fluorescent Dyes/Probes
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .

HY-D2738

BP Fluor 532 NHS ester

Fluorescent Dyes/Probes

BP Fluor 532 NHS ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 532 is a bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.

HY-D2768

BP Fluor 430 NHS ester

Fluorescent Dyes/Probes

BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.

HY-D0115

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester	Fluorescent Dyes/Probes
7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. 7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is a blue fluorescent dye for labeling proteins and nucleic acids .

HY-D2771

BP Fluor 405 NHS ester

Fluorescent Dyes/Probes

BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dyes/Probes
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dyes/Probes
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-15940

5(6)-Carboxyfluorescein 3 Publications Verification 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers	Fluorescent Dyes/Probes
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .

HY-D2761

DY-680-NHS ester	Fluorescent Dyes/Probes
DY-680-NHS ester is an amine reactive hydrophilic fluorochrome. It can be conjugated to an antibody with higher D/P ratio without causing fluorescence quenching and conjugate precipitation, and it is widely used in applications including western blotting, microscopy, flow cytometry, and cell-based assays. The spectrum has an excitation of 690nm and emission at 709nm.

HY-D2757

5(6)-Carboxyrhodamine 110 NHS ester	Fluorescent Dyes/Probes
5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).

HY-15941

5(6)-FITC

2 Publications Verification

Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers

Fluorescent Dyes/Probes

5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .

HY-D1363

BDP R6G maleimide

Fluorescent Dyes/Probes

BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .

HY-D1653

BDP 581/591 NHS ester

Fluorescent Dyes/Probes

BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.

HY-110210

BODIPY-FL NHS ester

BODIPY FL,SE

Fluorescent Dyes/Probes

BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .

HY-D2773

5-Carboxyrhodamine 110 NHS ester

Fluorescent Dyes/Probes

5-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS Ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. For many applications, the dye is preferred over 5-(6)-carboxyfluorescein NHS ester or FITC because of its exceptional photostability and fluorescence insensitivity to pH (4-9). Although the mixed isomers of Carboxyrhodamine 110 NHS Ester preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes.

Cat. No.	Product Name	Type

HY-155885

mPEG-amine (MW 40000) mPEG-NH2 (MW 40000)	Drug Delivery
mPEG-amine (MW 40000) (mPEG-NH2 (MW 40000)) is a monofunctional polyPEG with a terminal amine. The coupling between NHS ester and amine produces a stable amide bond. The amine moieties is also reactive with carboxyl in the presence of activating agent .

HY-131097

Malachite green isothiocyanate	Cell Assay Reagents
Malachite green isothiocyanate is an amine-reactive probe that reacts with amines to give the corresponding thiourea. Malachite green isothiocyanate is a reagent that has been used for the measurement of concentration of protein .

HY-W093254A

Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250)	3D Bioprinting
Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 250) is an amine-reactive crosslinking agent .

HY-W093254B

Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600)	3D Bioprinting
Poly(ethylene glycol) bis(carboxymethyl) ether (Mn 600) is an amine-reactive crosslinking agent .

HY-W441013

DSPE-PEG-NHS, MW 1000	Drug Delivery
DSPE-PEG-NHS, MW 1000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 1000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 1000 can be used in the study of drug delivery .

HY-140895B

Biotin-PEG-Amine (MW 10000) Biotin-PEG-NH2 (MW 10000)	Drug Delivery
Biotin-PEG-Amine (MW 10000) (Biotin-PEG-NH2 (MW 10000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895C

Biotin-PEG-Amine (MW 20000) Biotin-PEG-NH2 (MW 20000)	Drug Delivery
Biotin-PEG-Amine (MW 20000) (Biotin-PEG-NH2 (MW 20000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895D

Biotin-PEG-Amine (MW 40000) Biotin-PEG-NH2 (MW 40000)	Drug Delivery
Biotin-PEG-Amine (MW 40000) (Biotin-PEG-NH2 (MW 40000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-140895A

Biotin-PEG-Amine (MW 5000) Biotin-PEG-NH2 (MW 5000)	Drug Delivery
Biotin-PEG-Amine (MW 5000) (Biotin-PEG-NH2 (MW 5000)) is a biotin PEG polymer containing a free amine group (-NH2). The amine group is reactive with an activated NHS ester via formation of an amide bond. Biotin-labeled compounds can then be linked to avidin or streptavidin for further purification or detection .

HY-W1048567H

mPEG-SCM (MW 3400)	Drug Delivery
mPEG-SCM (MW 3400) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567

mPEG-SCM (MW 1000)	Drug Delivery
mPEG-SCM (MW 1000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567B

mPEG-SCM (MW 5000)	Drug Delivery
mPEG-SCM (MW 5000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567E

mPEG-SCM (MW 40000)	Drug Delivery
mPEG-SCM (MW 40000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567D

mPEG-SCM (MW 20000)	Drug Delivery
mPEG-SCM (MW 20000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567C

mPEG-SCM (MW 10000)	Drug Delivery
mPEG-SCM (MW 10000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048567A

mPEG-SCM (MW 2000)	Drug Delivery
mPEG-SCM (MW 2000) is a high quality amine-reactive PEG product with a stable non-degradable functional group between the PEG polymer chain and the NHS ester .

HY-W1048547H

HOOC-PEG-NH2 (MW 1000)

HOOC-PEG-amine (MW 1000)

Drug Delivery

HOOC-PEG-NH2 (MW 1000) (HOOC-PEG-Amine (MW 1000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547E

HOOC-PEG-NH2 (MW 20000)

HOOC-PEG-amine (MW 20000)

Drug Delivery

HOOC-PEG-NH2 (MW 20000) (HOOC-PEG-Amine (MW 20000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547A

HOOC-PEG-NH2 (MW 2000)

HOOC-PEG-amine (MW 2000)

Drug Delivery

HOOC-PEG-NH2 (MW 2000) (HOOC-PEG-Amine (MW 2000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547J

HOOC-PEG-NH2 (MW 40000)

HOOC-PEG-amine (MW 40000)

Drug Delivery

HOOC-PEG-NH2 (MW 40000) (HOOC-PEG-Amine (MW 40000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547I

HOOC-PEG-NH2 (MW 3400)

HOOC-PEG-amine (MW 3400)

Drug Delivery

HOOC-PEG-NH2 (MW 3400) (HOOC-PEG-Amine (MW 3400)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547C

HOOC-PEG-NH2 (MW 5000)

HOOC-PEG-amine (MW 5000)

Drug Delivery

HOOC-PEG-NH2 (MW 5000) (HOOC-PEG-Amine (MW 5000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048547D

HOOC-PEG-NH2 (MW 10000)

HOOC-PEG-amine (MW 10000)

Drug Delivery

HOOC-PEG-NH2 (MW 10000) (HOOC-PEG-Amine (MW 10000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .

HY-W1048843B

4-Arm PEG-NH2 (MW 10000) 4-Arm PEG-amine (MW 10000)	Drug Delivery
4-Arm PEG-NH2 (MW 10000) (4-Arm PEG-amine (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843A

4-Arm PEG-NH2 (MW 5000)	Drug Delivery
4-Arm PEG-NH2 (MW 5000) (4-Arm PEG-amine (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519B

4-Arm PEG-NH2.HCl (MW 20000) 4-Arm PEG-amine HCL salt (MW 20000)	Drug Delivery
4-Arm PEG-NH2 HCl (MW 20000) (4-Arm PEG-amine HCL salt (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843C

4-Arm PEG-NH2 (MW 20000) 4-Arm PEG-amine (MW 20000)	Drug Delivery
4-Arm PEG-NH2 (MW 20000) (4-Arm PEG-amine (MW 20000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519C

4-Arm PEG-NH2.HCl (MW 40000) 4-Arm PEG-amine HCL salt (MW 40000)	Drug Delivery
4-Arm PEG-NH2 HCl (MW 40000) (4-Arm PEG-amine HCL salt (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519

4-Arm PEG-NH2.HCl (MW 5000) 4-Arm PEG-amine HCL salt (MW 5000)	Drug Delivery
4-Arm PEG-NH2 HCl (MW 5000) (4-Arm PEG-amine HCL salt (MW 5000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048843D

4-Arm PEG-NH2 (MW 40000) 4-Arm PEG-amine (MW 40000)	Drug Delivery
4-Arm PEG-NH2 (MW 40000) (4-Arm PEG-amine (MW 40000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048519A

4-Arm PEG-NH2.HCl (MW 10000) 4-Arm PEG-amine HCL salt (MW 10000)	Drug Delivery
4-Arm PEG-NH2 HCl (MW 10000) (4-Arm PEG-amine HCL salt (MW 10000)) is a multi-arm PEG derivative with amine groups at each end of four arms attached to a pentaerythritol core. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W441002

DSPE-succinic acid	Drug Delivery
DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .

HY-W1048526C

8-Arm PEG-NH2 HCL (MW 10000) 8-Arm PEG-amine HCL salt (MW 10000)	Drug Delivery
8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525B

8-Arm PEG-NH2 (MW 40000) 8-Arm PEG-amine (MW 40000)	Drug Delivery
8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526

8-Arm PEG-NH2 HCL (MW 5000) 8-Arm PEG-amine HCL salt (MW 5000)	Drug Delivery
8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525C

8-Arm PEG-NH2 (MW 10000) 8-Arm PEG-amine (MW 10000)	Drug Delivery
8-Arm PEG-NH2 (MW 10000) (8-Arm PEG-Amine (MW 10000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526B

8-Arm PEG-NH2 HCL (MW 40000) 8-Arm PEG-amine HCL salt (MW 40000)	Drug Delivery
8-Arm PEG-NH2 (MW 40000) (8-Arm PEG-Amine (MW 40000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048526A

8-Arm PEG-NH2 HCL (MW 20000) 8-Arm PEG-amine HCL salt (MW 20000)	Drug Delivery
8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) HCL is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525

8-Arm PEG-NH2 (MW 5000) 8-Arm PEG-amine (MW 5000)	Drug Delivery
8-Arm PEG-NH2 (MW 5000) (8-Arm PEG-Amine (MW 5000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W1048525A

8-Arm PEG-NH2 (MW 20000) 8-Arm PEG-amine (MW 20000)	Drug Delivery
8-Arm PEG-NH2 (MW 20000) (8-Arm PEG-Amine (MW 20000)) is a multi-arm PEG derivative with amino groups at each end of the eight arms. The reactive primary amine or NH2 groups can react rapidly with activated carboxylic acids such as NHS esters to form stable amide bonds .

HY-W054259

BFMO

N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide

Biochemical Assay Reagents

BFMO is a bidentate ligand for copper (Cu) catalysts that can effectively promote copper-catalyzed N-arylation coupling reactions of (hetero)aryl bromides with aniline, cyclic secondary amines, and acyclic secondary amines. BFMO coordinates with copper ions to form stable catalytically active species, which reduces the activation energy of the reaction and improves the reactivity of the substrate. It exhibits excellent selectivity for coupling of acyclic secondary amines with large steric hindrance, and can achieve direct monoarylation of piperazine with (hetero)aryl bromides to generate important pharmaceutical structural units .

HY-W440884

DSPE-PEG-Ald (MW 3400)	Drug Delivery
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.

HY-W1048549E

HOOC-PEG-SH (MW 20000) HOOC-PEG-Thiol (MW 20000)	Drug Delivery
HOOC-PEG-SH (MW 20000) (HOOC-PEG-Thiol (MW 20000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .

HY-W1049075H

mPEG-pALD (MW 3400)

Drug Delivery

mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075E

mPEG-pALD (MW 2000)

Drug Delivery

mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1048549A

HOOC-PEG-SH (MW 2000) HOOC-PEG-Thiol (MW 2000)	Drug Delivery
HOOC-PEG-SH (MW 2000) (HOOC-PEG-Thiol (MW 2000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .

HY-W1048549B

HOOC-PEG-SH (MW 3400) HOOC-PEG-Thiol (MW 3400)	Drug Delivery
HOOC-PEG-SH (MW 3400) (HOOC-PEG-Thiol (MW 3400)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .

HY-W1048549C

HOOC-PEG-SH (MW 5000) HOOC-PEG-Thiol (MW 5000)	Drug Delivery
HOOC-PEG-SH (MW 5000) (HOOC-PEG-Thiol (MW 5000)) is a reactive thiol PEG derivative with a terminal carboxyl group. The carboxyl group can react with amine or hydroxyl groups to form a stable amide bond or an unstable ester bond. The PEG linkage between the thiol and carboxyl groups has good water solubility, flexible linker distance and higher stability .

HY-W1049075A

mPEG-pALD (MW 5000)

Drug Delivery

mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

HY-W1049075C

mPEG-pALD (MW 20000)

Drug Delivery

mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .

Cat. No.	Product Name		Classification

HY-140339

ANB-NOS		PROTAC Synthesis Azide
ANB-NOS is a heterobifunctional crosslinker that contain an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide .

HY-141175

TCO-PNB ester		PROTAC Synthesis TCO
TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group .

HY-D2746

Cy5.5 bis-NHS ester		Azide
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.

HY-172516

1-Palmitoyl-2-(propargylacetyl)-sn-glycero-3-phosphocholine		Alkynes
1-Palmitoyl-2-(propargylacetyl)-sn-glycero-3-phosphocholine is a phosphocholine containing an azide-reactive propargyl on one of its tails and a positively charged quaternary amine head.

HY-W591390

6-Azidohexanoic acid STP ester		Azide
6-Azidohexanoic Acid STP Ester is an amine-reactive, water-soluble labeling reagent with an azide group and a terminal 4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) group. 6-Azidohexanoic Acid STP Ester is used to modify proteins, antibodies, and other amine-containing biopolymers in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. STP esters can react with primary amines, forming covalent amide bonds, and typically display much better stability toward hydrolysis in aqueous media, resulting in more efficiency and better reproducible labeling of biopolymers.

Cat. No.	Product Name		Classification

HY-W441002

DSPE-succinic acid		Phospholipids
DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .

HY-W440927

Stearic acid-PEG-NHS, MW 2000		Pegylated Lipids
Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.

HY-W441011

DSPE-NHS		Phospholipids
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .

HY-W441013

DSPE-PEG-NHS, MW 1000		Pegylated Lipids
DSPE-PEG-NHS, MW 1000 is a PEG-modified phospholipid derivative that can be used to prepare liposomes. DSPE-PEG-NHS, MW 1000 is commonly employed as a linker molecule for the surface modification of liposomes to confer targeting capabilities. DSPE-PEG-NHS, MW 1000 can be used in the study of drug delivery .

HY-W441005

Amino-Gly-Gly-DSPE hydrochloride		Phospholipids
Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

HY-W440991

DOPE-PEG-Amine (MW 2000)		Pegylated Lipids
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.

HY-W440883

DSPE-PEG-Ald, MW 2000		Pegylated Lipids
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.

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